5,576 research outputs found
Factorization and Scaling in Hadronic Diffraction
In standard Regge theory with a pomeron intercept a(0)=1+\epsilon, the
contribution of the tripe-pomeron amplitude to the t=0 differential cross
section for single diffraction dissociation has the form d\sigma/dM^2(t=0) \sim
s^{2\epsilon}/(M^2)^{1+\epsilon}. For \epsilon>0, this form, which is based on
factorization, does not scale with energy. From an analysis of p-p and p-pbar
data from fixed target to collider energies, we find that such scaling actually
holds, signaling a breakdown of factorization. Phenomenologically, this result
can be obtained from a scaling law in diffraction, which is embedded in the
hypothesis of pomeron flux renormalization introduced to unitarize the triple
pomeron amplitude.Comment: 39 pages, Latex, 16 figure
GEM operation in helium and neon at low temperatures
We study the performance of Gas Electron Multipliers (GEMs) in gaseous He, Ne
and Ne+H2 at temperatures in the range of 2.6-293 K. In He, at temperatures
between 62 and 293 K, the triple-GEM structures often operate at rather high
gains, exceeding 1000. There is an indication that this high gain is achieved
by Penning effect in the gas impurities released by outgassing. At lower
temperatures the gain-voltage characteristics are significantly modified
probably due to the freeze-out of impurities. In particular, the double-GEM and
single-GEM structures can operate down to 2.6 K at gains reaching only several
tens at a gas density of about 0.5 g/l; at higher densities the maximum gain
drops further. In Ne, the maximum gain also drops at cryogenic temperatures.
The gain drop in Ne at low temperatures can be reestablished in Penning
mixtures of Ne+H2: very high gains, exceeding 10000, have been obtained in
these mixtures at 50-60 K, at a density of 9.2 g/l corresponding to that of
saturated Ne vapor near 27 K. The results obtained are relevant in the fields
of two-phase He and Ne detectors for solar neutrino detection and electron
avalanching at low temperatures.Comment: 13 pages, 14 figures. Accepted for publishing in Nucl. Instr. and
Meth.
Improved detection of differentially represented DNA barcodes for high-throughput clonal phenomics
Cellular DNA barcoding has become a popular approach to study heterogeneity of cell populations and to identify clones with differential response to cellular stimuli. However, there is a lack of reliable methods for statistical inference of differentially responding clones. Here, we used mixtures of DNA-barcoded cell pools to generate a realistic benchmark read count dataset for modelling a range of outcomes of clone-tracing experiments. By accounting for the statistical properties intrinsic to the DNA barcode read count data, we implemented an improved algorithm that results in a significantly lower false-positive rate, compared to current RNA-seq data analysis algorithms, especially when detecting differentially responding clones in experiments with strong selection pressure. Building on the reliable statistical methodology, we illustrate how multidimensional phenotypic profiling enables one to deconvolute phenotypically distinct clonal subpopulations within a cancer cell line. The mixture control dataset and our analysis results provide a foundation for benchmarking and improving algorithms for clone-tracing experiments
Single electron emission in two-phase xenon with application to the detection of coherent neutrino-nucleus scattering
We present an experimental study of single electron emission in ZEPLIN-III, a
two-phase xenon experiment built to search for dark matter WIMPs, and discuss
applications enabled by the excellent signal-to-noise ratio achieved in
detecting this signature. Firstly, we demonstrate a practical method for
precise measurement of the free electron lifetime in liquid xenon during normal
operation of these detectors. Then, using a realistic detector response model
and backgrounds, we assess the feasibility of deploying such an instrument for
measuring coherent neutrino-nucleus elastic scattering using the ionisation
channel in the few-electron regime. We conclude that it should be possible to
measure this elusive neutrino signature above an ionisation threshold of
3 electrons both at a stopped pion source and at a nuclear reactor.
Detectable signal rates are larger in the reactor case, but the triggered
measurement and harder recoil energy spectrum afforded by the accelerator
source enable lower overall background and fiducialisation of the active
volume
Transition between nuclear and quark-gluon descriptions of hadrons and light nuclei
We provide a perspective on studies aimed at observing the transition between
hadronic and quark-gluonic descriptions of reactions involving light nuclei. We
begin by summarizing the results for relatively simple reactions such as the
pion form factor and the neutral pion transition form factor as well as that
for the nucleon and end with exclusive photoreactions in our simplest nuclei. A
particular focus will be on reactions involving the deuteron. It is noted that
a firm understanding of these issues is essential for unraveling important
structure information from processes such as deeply virtual Compton scattering
as well as deeply virtual meson production. The connection to exotic phenomena
such as color transparency will be discussed. A number of outstanding
challenges will require new experiments at modern facilities on the horizon as
well as further theoretical developments.Comment: 37 pages, 17 figures, submitted to Reports on Progress in Physic
Cascaded two-photon nonlinearity in a one-dimensional waveguide with multiple two-level emitters
We propose and theoretically investigate a model to realize cascaded optical
nonlinearity with few atoms and photons in one-dimension (1D). The optical
nonlinearity in our system is mediated by resonant interactions of photons with
two-level emitters, such as atoms or quantum dots in a 1D photonic waveguide.
Multi-photon transmission in the waveguide is nonreciprocal when the emitters
have different transition energies. Our theory provides a clear physical
understanding of the origin of nonreciprocity in the presence of cascaded
nonlinearity. We show how various two-photon nonlinear effects including
spatial attraction and repulsion between photons, background fluorescence can
be tuned by changing the number of emitters and the coupling between emitters
(controlled by the separation).Comment: 6 pages, 4 figure
First Measurement of Coherent Elastic Neutrino-Nucleus Scattering on Argon
We report the first measurement of coherent elastic neutrino-nucleus
scattering (\cevns) on argon using a liquid argon detector at the Oak Ridge
National Laboratory Spallation Neutron Source. Two independent analyses prefer
\cevns over the background-only null hypothesis with greater than
significance. The measured cross section, averaged over the incident neutrino
flux, is (2.2 0.7) 10 cm -- consistent with the
standard model prediction. The neutron-number dependence of this result,
together with that from our previous measurement on CsI, confirms the existence
of the \cevns process and provides improved constraints on non-standard
neutrino interactions.Comment: 8 pages, 5 figures with 2 pages, 6 figures supplementary material V3:
fixes to figs 3,4 V4: fix typo in table 1, V5: replaced missing appendix, V6:
fix Eq 1, new fig 3, V7 final version, updated with final revision
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