7 research outputs found

    The metaphor of the professional self-determination: the interrelationship of individual and personal characteristics, and vocational choice

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    The article presents the data of research of interrelation of professional self-determination and features of individual and personal characteristics of individuals on the example of the choice of the profession of “psychologist” in different age groups: high school students, psychology students and practitioners. Also considered the peculiarities of the choice of metaphors to describe the category of “Self” image” and “I'm a professional”. The study was done on a sample of 55 people using a set of three methods. Based on the results, it is concluded that some personal characteristics can indirectly affect professional self-determination. For example, “altruistic” people tend to choose “helping” professions, while those with high indicators on the scale of “Openness to new experience” are more suited to creatively oriented work. It is assumed that the relationship between the use of certain cognitive metaphors and professional choice determines some inclusion of images of different “Self” images” in the process of self-determination, but for the conclusions about the integration of personal and professional self-determination in cognitive metaphors further research is needed

    Blood serum concentrations of total proteins and main protein fractions in weaning rabbits experimentally infected with E. coli

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    The objective of the present Study was to evaluate the changes in the concentrations of major blood proteins associated with experimental E. coli infection in weaning rabbits. For that, in the assay group. 12 weaning White New Zealand rabbits (45 days old) were orally infected with a bacteria] suspension of enteropathogenic E. coli strain type O15:H- (6.10(7) cfu) whereas the 6 control rabbits received only 0.9% NaCl solution. Serum total protein. albumin, globulin and lysozyme concentrations as well as plasma fibrinogen concentrations were measured before (0h) and 1, 3, 7, 11 18 and 30 days after oral treatment. In parallel. presence of coliforms was investigated in rectal samples on clays 0, 1, 6, 11, 16, 25 and 30. Infected rabbits began to excrete E. coli strains on (lay 2 after administration, whereas the first signs of diarrhoea were observed on day 5. Between days 11 and 18 severe diarrhoea was found in all rabbits and then clinical signs gradually disappeared although 3 rabbits continue to excrete the bacteria on day 30. In inoculated rabbits, hypoproteinemia and hypo-albuminemia compared to control values were evidenced since the 7(th) day whereas the blood concentrations of lysozyme and fibrinogen at a lesser extend were dramatically increased on days 11 - 18 and on days 3-18 respectively, leading to a significantly lowered albumin/globulin ratio since the 11(th) day. These results confirm that albumin is a negative acute phase protein (APP) while fibrinogen and lysozyme were 2 positive APP in response to an experimental bacterial infection in rabbit

    Blood serum concentrations of total proteins and main protein fractions in weaning rabbits experimentally infected with E. coli

    No full text
    The objective of the present study was to evaluate the changes in the concentrations of major blood proteins associated with experimental E. coli infection in weaning rabbits. For that, in the assay group. 12 weaning White New Zealand rabbits (45 days old) were orally infected with a bacterial suspension of enteropathogenic E. coli strain type O15:H- (6.107 cfu) whereas the 6 control rabbits received only 0.9% NaCI solution. Serum total protein, albumin, globulin and lysozyme concentrations as well as plasma fibrinogen concentrations were measured before (0h) and I, 3, 7, 11, 18 and 30 days after oral treatment. In parallel, presence of coliforms was investigated in rectal samples on days 0, 1.6. 11, 16, 25 and 30. Infected rabbits began to excrete E. coli strains on day 2 after administration, whereas the first signs of diarrhoea were observed on day 5. Between days 11 and 18 severe diarrhoea was found in all rabbits and then clinical signs gradually disappeared although 3 rabbits continue to excrete the bacteria on day 30. In inoculated rabbits, hypoproteinemia and hypo-albuminemia compared to control values were evidenced since the 7th day whereas the blood concentrations of lysozyme and fibrinogen at a lesser extend were dramatically increased on days 11-18 and on days 3-18 respectively, leading to a significantly lowered albumin/globulin ratio since the 11th day. These results confirm that albumin is a negative acute phase protein (APP) while fibrinogen and lysozyme were 2 positive APP in response to an experimental bacterial infection in rabbits

    Variations of acute phase protein (haptoglobin, fibrinogen and ceruloplasmin) concentrations in weaning rabbits after experimental infection with E.coli

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    Infections with E. coli are a common cause of diarrhoea in weaning rabbits. The present study was conducted to evaluate the changes in the blood concentrations of haptoglobin (Hp), ceruloplasmin (Cp) and fibrinogen (Fb) during experimentally induced E. coli infection in weaning rabbits. A total of 18 rabbits, 40-45 days old and weaned at 4 weeks were used: 12 were inoculated with the E. coli strain type 015:H- suspension (6. 107 cfu) and the 6 remained rabbits served as controls. Blood samples for acute phase proteins (APPs) analysis were collected before (0 h) and at 24 th and 72th hours and on days 7, 11, 18 and 30 after inoculation. The presence of coliforms was investigated in rectal samples on days 1, 6, 11, 16, 25 and 31. The excretion of the 015:H- type began 2 days after experimental challenge in 3 rabbits and was intensified on day 3 whereas mild to severe diarrhoea episodes were observed between the 5 th day to the 21st day in all rabbits except 2. In parallel, bacterial excretion gradually declined. Moreover, Hp concentrations dramatically increased after E. coli inoculation since 24th hours, reached maximal values on day 7 (multiplied by a factor 9) and remained significantly elevated compared to basal values until the 30th day. By contrast, significant changes in Fb and Cp concentrations compared to initial values appeared later (on days 3 and 7 respectively), less intense (maximal concentrations observed on day 11 were only roughly doubled) and were more transient (normal values were obtained on days 30 and 18 respectively). Increases of all APP concentrations were associated with the intensity of the diarrhoea. Moderate positive correlations were evidenced between Hp and Cp or Fb concentrations while Cp and Fb concentrations were strongly correlated. The time course and the magnitude of changes of these APPs induce to consider Cp and Fb as slow reacting positive APPs while Hp has to be classified as a rapid major positive APP useful for early detection of bacterial infections in weaning rabbits, before the clinical appearance of diarrhoea and faecal excretion of E. coli
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