Character association in paprika (Capsicum annuum/i L.)1

Correlation studies conducted in 94 diverse genotypes of paprika (Capsicum annuum) grown at Lam (Andhra Pradesh) indicated that dry fruit yield plant-1 showed significant and positive association with plant height, plant spread, number of fruits plant-1, fruit girth, seeds fruit-1 and capsanthin content. Path coefficient studies revealed that number of fruits plant-1 had the highest positive direct effect on dry fruit yield plant-1. Number of fruits plant-1, plant height, plant spread, number of seeds fruit-1, days to maturity and capsanthin content (in the given order) were important yield and quality components having direct bearing on dry fruit yield and hence can be considered while breeding for improved yield in paprika

Profiling of purified autophagic vesicle degradome in the maturing and aging brain.

Autophagy disorders prominently affect the brain, entailing neurodevelopmental and neurodegenerative phenotypes in adolescence or aging, respectively. Synaptic and behavioral deficits are largely recapitulated in mouse models with ablation of autophagy genes in brain cells. Yet, the nature and temporal dynamics of brain autophagic substrates remain insufficiently characterized. Here, we immunopurified LC3-positive autophagic vesicles (LC3-pAVs) from the mouse brain and proteomically profiled their content. Moreover, we characterized the LC3-pAV content that accumulates after macroautophagy impairment, validating a brain autophagic degradome. We reveal selective pathways for aggrephagy, mitophagy, and ER-phagy via selective autophagy receptors, and the turnover of numerous synaptic substrates, under basal conditions. To gain insight into the temporal dynamics of autophagic protein turnover, we quantitatively compared adolescent, adult, and aged brains, revealing critical periods of enhanced mitophagy or degradation of synaptic substrates. Overall, this resource unbiasedly characterizes the contribution of autophagy to proteostasis in the maturing, adult, and aged brain