22,677 research outputs found
Parton Production Via Vacuum Polarization
We discuss the production mechanism of partons via vacuum polarization during
the very early, gluon dominated phase of an ultrarelativistic heavy-ion
collision in the framework of the background field method of quantum
chromodynamics.Comment: 3 pages, Latex, 3 figures (eps), to be published in JPhysG, SQM2001
proceeding
A Computational-Experimental Approach Identifies Mutations That Enhance Surface Expression of an Oseltamivir-Resistant Influenza Neuraminidase
The His274 → Tyr (H274Y) oseltamivir (Tamiflu) resistance mutation causes a substantial decrease in the total levels of surface-expressed neuraminidase protein and activity in early isolates of human seasonal H1N1 influenza, and in the swine-origin pandemic H1N1. In seasonal H1N1, H274Y only became widespread after the occurrence of secondary mutations that counteracted this decrease. H274Y is currently rare in pandemic H1N1, and it remains unclear whether secondary mutations exist that might similarly counteract the decreased neuraminidase surface expression associated with this resistance mutation in pandemic H1N1. Here we investigate the possibility of predicting such secondary mutations. We first test the ability of several computational approaches to retrospectively identify the secondary mutations that enhanced levels of surface-expressed neuraminidase protein and activity in seasonal H1N1 shortly before the emergence of oseltamivir resistance. We then use the most successful computational approach to predict a set of candidate secondary mutations to the pandemic H1N1 neuraminidase. We experimentally screen these mutations, and find that several of them do indeed partially counteract the decrease in neuraminidase surface expression caused by H274Y. Two of the secondary mutations together restore surface-expressed neuraminidase activity to wildtype levels, and also eliminate the very slight decrease in viral growth in tissue-culture caused by H274Y. Our work therefore demonstrates a combined computational-experimental approach for identifying mutations that enhance neuraminidase surface expression, and describes several specific mutations with the potential to be of relevance to the spread of oseltamivir resistance in pandemic H1N1
Entanglement measurement with discrete multiple coin quantum walks
Within a special multi-coin quantum walk scheme we analyze the effect of the
entanglement of the initial coin state. For states with a special entanglement
structure it is shown that this entanglement can be meausured with the mean
value of the walk, which depends on the i-concurrence of the initial coin
state. Further on the entanglement evolution is investigated and it is shown
that the symmetry of the probability distribution is reflected by the symmetry
of the entanglement distribution.Comment: 9 pages, IOP styl
Schwinger Mechanism for Gluon Pair Production in the Presence of Arbitrary Time Dependent Chromo-Electric Field
We study Schwinger mechanism for gluon pair production in the presence of
arbitrary time-dependent chromo-electric background field with
arbitrary color index =1,2,...8 in SU(3) by directly evaluating the path
integral. We obtain an exact expression for the probability of non-perturbative
gluon pair production per unit time per unit volume and per unit transverse
momentum from arbitrary . We show that the
tadpole (or single gluon) effective action does not contribute to the
non-perturbative gluon pair production rate . We find
that the exact result for non-perturbative gluon pair production is independent
of all the time derivatives where
and has the same functional dependence on two casimir invariants
and as the constant
chromo-electric field result with the replacement: . This
result may be relevant to study the production of a non-perturbative
quark-gluon plasma at RHIC and LHC.Comment: 13 pages latex, Published in European Physical Journal
General Form of the Color Potential Produced by Color Charges of the Quark
Constant electric charge satisfies the continuity equation where is the current density of the electron.
However, the Yang-Mills color current density of the quark
satisfies the equation which is not a continuity
equation () which implies that a color charge
of the quark is not constant but it is time dependent where
are color indices. In this paper we derive general form of color
potential produced by color charges of the quark. We find that the general form
of the color potential produced by the color charges of the quark at rest is
given by \Phi^a(x) =A_0^a(t,{\bf x}) =\frac{q^b(t-\frac{r}{c})}{r}\[\frac{{\rm
exp}[g\int dr \frac{Q(t-\frac{r}{c})}{r}] -1}{g \int dr
\frac{Q(t-\frac{r}{c})}{r}}\]_{ab} where integration is an indefinite
integration, ~~ , ~~, ~~ is the retarded time, ~~ is the speed
of light, ~~ is the position of the quark at the retarded
time and the repeated color indices (=1,2,...8) are summed. For constant
color charge we reproduce the Coulomb-like potential
which is consistent with the Maxwell theory where
constant electric charge produces the Coulomb potential
.Comment: Final version, two more sections added, 45 pages latex, accepted for
publication in JHE
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