956 research outputs found
Random walks and market efficiency in Chinese and Indian equity markets
Hypothesis of Market Efficiency is an important concept for the investors
across the globe holding diversified portfolios. With the world economy getting
more integrated day by day, more people are investing in global emerging
markets. This means that it is pertinent to understand the efficiency of these
markets. This paper tests for market efficiency by studying the impact of
global financial crisis of 2008 and the recent Chinese crisis of 2015 on stock
market efficiency in emerging stock markets of China and India. The data for
last 20 years was collected from both Bombay Stock Exchange (BSE200) and the
Shanghai Stock Exchange Composite Index and divided into four sub-periods, i.e.
before financial crisis period (period-I), during recession (period-II), after
recession and before Chinese Crisis (periodIII) and from the start of Chinese
crisis till date (period- IV). Daily returns for the SSE and BSE were examined
and tested for randomness using a combination of auto correlation tests, runs
tests and unit root tests (Augmented Dickey-Fuller) for the entire sample
period and the four sub-periods. The evidence from all these tests supports
that both the Indian and Chinese stock markets do not exhibit weak form of
market efficiency. They do not follow random walk overall and in the first
three periods (1996 till the 2015) implying that recession did not impact the
markets to a great extent, although the efficiency in percentage terms seems to
be increasing after the global financial crisis of 2008
Range Monitoring with Photo-points
6 pp., 2 photosPhoto-points provide a way for owners/managers to monitor rangeland health with a minimum of time and expense. This publication explains when, where and how often to photograph rangeland points, how to set up a photo point, and how to interpret the photographs
Stocking Rate Decisions
12 pp., 2 graphs, 3 charts, 1 table, 2 photosStocking rate determines animal performance, financial return, and the long-term condition of the range. This publication discusses the factors that affect stocking rate, the relationship of stocking rate to carrying capacity, the amount of forage that should be left ungrazed in order to preserve the resource, and how ranchers can determine actual forage production. Knowing forage production is the key to selecting the proper stocking rate
Mathematical modelling of fluid flow and solute transport to define operating parameters for in vitro perfusion cell culture systems
In recent years, there has been a move away from the use of static in vitro two-dimensional cell culture models for testing the chemical safety and efficacy of drugs. Such models are increasingly being replaced by more physiologically relevant cell culture systems featuring dynamic flow and/or three-dimensional structures of cells. While it is acknowledged that such systems provide a more realistic environment within which to test drugs, progress is being hindered by a lack of understanding of the physical and chemical environment that the cells are exposed to. Mathematical and computational modelling may be exploited in this regard to unravel the dependency of the cell response on spatio-temporal differences in chemical and mechanical cues, thereby assisting with the understanding and design of these systems. In this paper, we present a mathematical modelling framework that characterizes the fluid flow and solute transport in perfusion bioreactors featuring an inlet and an outlet. To demonstrate the utility of our model, we simulated the fluid dynamics and solute concentration profiles for a variety of different flow rates, inlet solute concentrations and cell types within a specific commercial bioreactor chamber. Our subsequent analysis has elucidated the basic relationship between inlet flow rate and cell surface flow speed, shear stress and solute concentrations, allowing us to derive simple but useful relationships that enable prediction of the behaviour of the system under a variety of experimental conditions, prior to experimentation. We describe how the model may used by experimentalists to define operating parameters for their particular perfusion cell culture systems and highlight some operating conditions that should be avoided. Finally, we critically comment on the limitations of mathematical and computational modelling in this field, and the challenges associated with the adoption of such methods
Continuous cocrystallization of benzoic acid and isonicotinamide by mixing-induced supersaturation : exploring opportunities between reactive and antisolvent crystallization concepts
This study combines reactive and antisolvent crystallization concepts via mixing-induced supersaturation to demonstrate a wider range of options for solvent system selection in multicomponent crystallization. This approach was applied to investigate continuous crystallization of 1:1 and 2:1 cocrystals of benzoic acid and isonicotinamide. Design of Experiments was used to identify conditions where pure cocrystal phases are obtained and a continuous mixing-induced cocrystallization process was implemented to selectively produce either 1:1 or 2:1 cocrystals
Modelling chemistry and biology after implantation of a drug-eluting stent. Part I: Drug transport
Drug-eluting stents have been used widely to prevent restenosis of arteries following percutaneous balloon angioplasty. Mathematical modelling plays an important role in optimising the design of these stents to maximise their efficiency. When designing a drug-eluting stent system, we expect to have a sufficient amount of drug being released into the artery wall for a sufficient period to prevent restenosis. In this paper, a simple model is considered to provide an elementary description of drug release into artery tissue from an implanted stent. From the model, we identified a parameter regime to optimise the system when preparing the polymer coating. The model provides some useful order of magnitude estimates for the key quantities of interest. From the model, we can identify the time scales over which the drug traverses the artery wall and empties from the polymer coating, as well as obtain approximate formulae for the total amount of drug in the artery tissue and the fraction of drug that has released from the polymer. The model was evaluated by comparing to in-vivo experimental data and good agreement was found
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