761 research outputs found
Influence of Urban Landscapes on Population Dynamics in a Short-Distance Migrant Mosquito: Evidence for the Dengue Vector Aedes aegypti
Worldwide, 2.5 billion people are at risk for dengue infection, with no vaccine or treatment available. Thus dengue prevention is largely focused on controlling its mosquito vector, Aedes aegypti. Traditional mosquito control approaches typically include insecticide applications and breeding site source reduction. Presently, novel dengue control measures including the sterile insect technique and population replacement with dengue-incompetent transgenic mosquitoes are also being considered. Success of all population control programs is in part dependent upon understanding mosquito population ecology, including how anthropogenic effects on the urban landscape influence dispersal and expansion. We conducted a two year population genetic study examining how a major metropolitan highway impacts mosquito dispersal in Trinidad, West Indies. As evidenced by significant differentiation using both nuclear and mitochondrial DNA sequences, the highway acted as a significant barrier to dispersal. Our results suggest that anthropogenic landscape features can be used effectively to enhance population suppression/replacement measures by defining mosquito control zones along recognized landscape barriers that limit population dispersal
Effect of diabetes on acid and neutral triacylglycerol lipase and on lipoprotein lipase activities in isolated myocardial cells from rat heart
Post-transcriptional mechanisms are responsible for the reduction in lipoprotein lipase activity in cardiomyocytes from diabetic rat hearts
Calmodulin inhibits the protein kinase C-catalysed phosphorylation of an endogenous protein in A10 smooth-muscle cells
Characterizing the Adaptive Optics Off-Axis Point-Spread Function - I: A Semi-Empirical Method for Use in Natural-Guide-Star Observations
Even though the technology of adaptive optics (AO) is rapidly maturing,
calibration of the resulting images remains a major challenge. The AO
point-spread function (PSF) changes quickly both in time and position on the
sky. In a typical observation the star used for guiding will be separated from
the scientific target by 10" to 30". This is sufficient separation to render
images of the guide star by themselves nearly useless in characterizing the PSF
at the off-axis target position. A semi-empirical technique is described that
improves the determination of the AO off-axis PSF. The method uses calibration
images of dense star fields to determine the change in PSF with field position.
It then uses this information to correct contemporaneous images of the guide
star to produce a PSF that is more accurate for both the target position and
the time of a scientific observation. We report on tests of the method using
natural-guide-star AO systems on the Canada-France-Hawaii Telescope and Lick
Observatory Shane Telescope, augmented by simple atmospheric computer
simulations. At 25" off-axis, predicting the PSF full width at half maximum
using only information about the guide star results in an error of 60%. Using
an image of a dense star field lowers this error to 33%, and our method, which
also folds in information about the on-axis PSF, further decreases the error to
19%.Comment: 29 pages, 9 figures, accepted for publication in the PAS
Characterization of bovine aortic protein kinase C with histone and platelet protein P47 as substrates
Short-term incubation of cardiac myocytes with isoprenaline has no effect on heparin-releasable or cellular lipoprotein lipase activity
Activation of lipoprotein lipase in cardiac myocytes by glycosylation requires trimming of glucose residues in the endoplasmic reticulum
- …