The Lived Experience of Late-Stage Doctoral Student Attrition in Counselor Education

Doctoral student attrition occurs across academic disciplines and presents problems for noncompleting students and the programs from which they withdraw. The following research question guided the present study, What is the experience of doctoral attrition in counselor education? Six late-stage doctoral noncompleters from counselor education programs participated in research interviews that were analyzed using a grounded theory approach. Results showed two distinct types of attrition. Five participants reported a negative experience of encountering barriers that acted against the internal desire of the participants to obtain the doctorate. One participant reported a positive experience of an internal change that altered the priority of continuing in doctoral study. Results of the present study have implications for prospective and current doctoral students

Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients?

The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref. 8). SPM-1, a recently discovered MBL, was isolated from a juvenile leukemia patient residing in a hospital in San Palo, Brazil just prior to the patient succumbing to septicemia brought on by Pseudomonas aeruginosa expressing SPM-1 (ref. 8). Screening of the Johns Hopkins Compound library of 1,514 FDA or FAD approved drugs (ref. 1) identified a novel SPM-1 inhibitor that is synergistically compatible with meropenem. Using clinically achievable concentrations, meropenem coupled with nadifloxacin inhibits Pseudomonas aeruginosa expressing SPM-1. This shotgun approach to new drug discovery provided a prompt solution to the grave problem of antibiotic resistant pathogens that are thriving in hospitals today

A Geoarcheological Survey of the Proposed Plainview Hike and Bike Trail, Hale County, Texas

In March of 2005, the Texas Department of Transportation issued work authorization #575-01-SA005 to the Center for Archaeological Research (CAR) at the University of Texas at San Antonio to conduct a survey of areas affected by proposed improvements to the Plainview hike and bike trail in southern Plainview, Hale County, Texas. The survey was conduced under Texas Antiquities Permit #3707 between March 31 and April 7, 2005. Steve Tomka and Raymond Mauldin served as Principal Investigators. Trail construction included 2.0 miles of additional construction and 1.3 miles of improvements to existing trails. The Right-of-Way is 50 feet and extends from one to three feet below ground surface. Archeological services included a pedestrian survey, excavation of fifty-five auger tests placed no more than 100 m apart, and twenty-one Gradall trenches. Two of these trenches exposed the stratigraphy of Running Water Draw near the Plainview Site, 41HA1. Bulk samples were collected for OSL dating, diatoms analysis, and lithologic analysis for further examination of the age and stratigraphic context of the Plainview Site, which is a State Archeological Landmark, a National Landmark, and a National Register of Historic Places property. Site 41HA12 was re-examined with 10 mechanical auger tests and 1 trench, which found only recent alluvial and cultural deposition. No additional archeological sites were recorded. This report includes descriptions of the fieldwork, results of the special analyses performed on bulk sediment samples collected, and a discussion of the geomorphology of Running Water Draw with specific focus on the results from trenches excavated near the Plainview Site. The single artifact and all documents and photographs generated from this project are curated at the Center for Archaeological Research at The University of Texas at San Antonio

Long-term survival for a cohort of adults with cerebral palsy

The aim of this study was to investigate long-term survival and examine causes of death in adult patients with cerebral palsy (CP). A 1940–1950 birth cohort based on paediatric case referral allows for long-term survival follow-up. Survival is analyzed by birth characteristics and severity of disability from age 20 years (and age 2y for a subset of the data). Survival outcome compared with that expected in the general population based on English life tables. The main cohort consisted of 341 individuals, with 193 males and 148 females. Conditional on surviving to age 20 years, almost 85% of the cohort survived to age 50 years (a comparable estimate for the general population is 96%). Very few deaths were attributed to CP for those people dying over 20 years of age. Females survived better than males. However, females faced a greater increase in risk relative to the general population than did males. We conclude that survival outlook is good though lower than in the general population. The relative risk of death compared with the UK population decreases with age, although it shows some indication of rising again after age 50 years. Many more deaths were caused by diseases of the respiratory system among those dying in their 20s and 30s than would be expected in the general population. Many fewer deaths than expected in this age group are caused by injuries and accidents. For those people who die in their 40s and 50s, an increase in deaths due to diseases of the circulatory system and neoplasms is observed. More deaths than expected in this age group are due to diseases of the nervous system

Gamma-Ray Bursts Trace UV Metrics of Star Formation over 3 < z < 5

We present the first uniform treatment of long duration gamma-ray burst (GRB) host galaxy detections and upper limits over the redshift range 3<z<5, a key epoch for observational and theoretical efforts to understand the processes, environments, and consequences of early cosmic star formation. We contribute deep imaging observations of 13 GRB positions yielding the discovery of eight new host galaxies. We use this dataset in tandem with previously published observations of 31 further GRB positions to estimate or constrain the host galaxy rest-frame ultraviolet (UV; 1600 A) absolute magnitudes M_UV. We then use the combined set of 44 M_UV estimates and limits to construct the M_UV luminosity function (LF) for GRB host galaxies over 3<z<5 and compare it to expectations from Lyman break galaxy (LBG) photometric surveys with the Hubble Space Telescope. Adopting standard prescriptions for the luminosity dependence of galaxy dust obscuration (and hence, total star formation rate), we find that our LF is compatible with LBG observations over a factor of 600x in host luminosity, from M_UV = -22.5 mag to >-15.6 mag, and with extrapolations of the assumed Schechter-type LF well beyond this range. We review proposed astrophysical and observational biases for our sample, and find they are for the most part minimal. We therefore conclude, as the simplest interpretation of our results, that GRBs successfully trace UV metrics of cosmic star formation over the range 3<z<5. Our findings suggest GRBs are providing an accurate picture of star formation processes from z ~3 out to the highest redshifts.Comment: publ. ApJ 809 (2015) 76; 14 figures; replacement to reflect changes to v1 (rounding effects, diff. LF from Bouwens

At risk of being risky: The relationship between "brain age" under emotional states and risk preference.

Developmental differences regarding decision making are often reported in the absence of emotional stimuli and without context, failing to explain why some individuals are more likely to have a greater inclination toward risk. The current study (N=212; 10-25y) examined the influence of emotional context on underlying functional brain connectivity over development and its impact on risk preference. Using functional imaging data in a neutral brain-state we first identify the "brain age" of a given individual then validate it with an independent measure of cortical thickness. We then show, on average, that "brain age" across the group during the teen years has the propensity to look younger in emotional contexts. Further, we show this phenotype (i.e. a younger brain age in emotional contexts) relates to a group mean difference in risk perception - a pattern exemplified greatest in young-adults (ages 18-21). The results are suggestive of a specified functional brain phenotype that relates to being at "risk to be risky.

Radial-Electric-Field Piezoelectric Diaphragm Pumps

In a recently invented class of piezoelectric diaphragm pumps, the electrode patterns on the piezoelectric diaphragms are configured so that the electric fields in the diaphragms have symmetrical radial (along-the-surface) components in addition to through-the-thickness components. Previously, it was accepted in the piezoelectric-transducer art that in order to produce the out-of-plane bending displacement of a diaphragm needed for pumping, one must make the electric field asymmetrical through the thickness, typically by means of electrodes placed on only one side of the piezoelectric material. In the present invention, electrodes are placed on both sides and patterned so as to produce substantial radial as well as through-the-thickness components. Moreover, unlike in the prior art, the electric field can be symmetrical through the thickness. Tests have shown in a given diaphragm that an electrode configuration according to this invention produces more displacement than does a conventional one-sided electrode pattern. The invention admits of numerous variations characterized by various degrees of complexity. Figure 1 is a simplified depiction of a basic version. As in other piezoelectric diaphragm pumps of similar basic design, the prime mover is a piezoelectric diaphragm. Application of a suitable voltage to the electrodes on the diaphragm causes it to undergo out-of-plane bending. The bending displacement pushes a fluid out of, or pulls the fluid into, a chamber bounded partly by the diaphragm. Also as in other diaphragm pumps in general, check valves ensure that the fluid flows only in through one port and only out through another port

XMM-Newton and optical follow-up observations of three new polars from the Sloan Digital Sky Survey

We report follow-up XMM-Newton and optical observations of three new polars found in the Sloan Digital Sky Survey. Simple modeling of the X-ray spectra, and consideration of the details of the X-ray and optical lightcurves corroborate the polar nature of these three systems and provide further insights into their accretion characteristics. During the XMM-Newton observation of SDSS J072910.68+365838.3, X-rays are undetected apart from a probable flare event, during which we find both the typical hard X-ray bremsstrahlung component and a very strong line O VII (E=0.57 keV), but no evidence of a soft blackbody contribution. In SDSS J075240.45+362823.2 we identify an X-ray eclipse at the beginning of the observation, roughly in phase with the primary minimum of the optical broad band curve. The X-ray spectra require the presence of both hard and soft X-ray components, with their luminosity ratio consistent with that found in other recent XMM-Newton results on polars. Lastly, SDSS J170053.30+400357.6 appears optically as a very typical polar, however its large amplitude optical modulation is 180 degrees out of phase with the variation in our short X-ray lightcurve.Comment: 9 pages, 9 figures, accepted for publication in the ApJ (January 2005