300 research outputs found

    Sea surface temperature changes in the southern California borderlands during the last glacial-interglacial cycle

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    A variety of evidence suggests that average sea surface temperatures (SSTs) during the last glacial maximum in the California Borderlands region were significantly colder than during the Holocene. Planktonic foraminiferal δ18O evidence and average SST estimates derived by the modern analog technique indicate that temperatures were 6°-10°C cooler during the last glacial relative to the present. The glacial plankton assemblage is dominated by the planktonic foraminifer Neogloboquadrina pachyderma (sinistral coiling) and the coccolith Coccolithus pelagicus, both of which are currently restricted to subpolar regions of the North Pacific. The glacial-interglacial average SST change determined in this study is considerably larger than the 2°C change estimated by Climate: Long-Range Investigation, Mapping, and Prediction (CLIMAP) [1981]. We propose that a strengthened California Current flow was associated with the advance of subpolar surface waters into the Borderlands region during the last glacial

    Statistical properties of near‐surface flow in the California coastal transition zone

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    The article of record as published may be found at https://doi.org/10.1029/91JC01072During the summers of 1987 and 1988, 77 near-surface satellite-tracked drifters were deployed in or near cold filaments near Point Arena, California (39°N), and tracked for up to 6 months as part of the Coastal Transition Zone (CTZ) program. The drifters had large drogues centered at 15 m, and the resulting drifter trajectory data set has been analyzed in terms of its Eulerian and Lagrangian statistics. The CTZ drifter results show that the California Current can be characterized in summer and fall as a meandering coherent jet which on average flows southward to at least 30°N, the southern end of the study domain. From 39°N south to about 33°N, the typical core velocities are of O(50 cm s−1) and the current meanders have alongshore wavelengths of O (300 km) and onshore-offshore amplitude of O(100–200 km). The lateral movement of this jet leads to large eddy kinetic energies and large eddy diffusivities, especially north of 36°N. The initial onshore-offshore component of diffusivity is always greater than the alongshore component in the study domain, but at the southern end, the eddy diffusivity is more isotropic, with scalar single particle diffusivity (Kxx + Kyy) of O(8 × 107 cm2 s−1). The eddy diffusivity increases with increasing eddy energy. Finally, a simple volume budget for the 1988 filament observed near 37°N off Point Arena suggests that subduction can occur in a filament at an average rate of O (10 m d−1) some 200 km offshore, thus allowing the cold water initially in the filament core to sink below the warmer ambient water by the time the surface velocity core has turned back onshore. This process explains why satellite temperature and color imagery tend to “see” only flow proceeding offshore

    Computational Approaches and Analysis for a Spatio-Structural-Temporal Invasive Carcinoma Model

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    Spatio-temporal models have long been used to describe biological systems of cancer, but it has not been until very recently that increased attention has been paid to structural dynamics of the interaction between cancer populations and the molecular mechanisms associated with local invasion. One system that is of particular interest is that of the urokinase plasminogen activator (uPA) wherein uPA binds uPA receptors on the cancer cell surface, allowing plasminogen to be cleaved into plasmin, which degrades the extracellular matrix and this way leads to enhanced cancer cell migration. In this paper, we develop a novel numerical approach and associated analysis for spatio-structuro-temporal modelling of the uPA system for up to two-spatial and two-structural dimensions. This is accompanied by analytical exploration of the numerical techniques used in simulating this system, with special consideration being given to the proof of stability within numerical regimes encapsulating a central differences approach to approximating numerical gradients. The stability analysis performed here reveals instabilities induced by the coupling of the structural binding and proliferative processes. The numerical results expound how the uPA system aids the tumour in invading the local stroma, whilst the inhibitor to this system may impede this behaviour and encourage a more sporadic pattern of invasion.PostprintPeer reviewe

    Structured models of cell migration incorporating molecular binding processes

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    The dynamic interplay between collective cell movement and the various molecules involved in the accompanying cell signalling mechanisms plays a crucial role in many biological processes including normal tissue development and pathological scenarios such as wound healing and cancer. Information about the various structures embedded within these processes allows a detailed exploration of the binding of molecular species to cell-surface receptors within the evolving cell population. In this paper we establish a general spatio-temporal-structural framework that enables the description of molecular binding to cell membranes coupled with the cell population dynamics. We first provide a general theoretical description for this approach and then illustrate it with two examples arising from cancer invasion

    Perspective article: Actions to reconfigure food systems

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    There is broad agreement that current food systems are not on a sustainable trajectory that will enable us to reach the Sustainable Development Goals by 2030, particularly in the face of anthropogenic climate change. Guided by a consideration of some food system reconfigurations in the past, we outline an agenda of work around four action areas: rerouting old systems into new trajectories; reducing risks; minimising the environmental footprint of food systems; and realigning the enablers of change needed to make new food systems function. Here we highlight food systems levers that, along with activities within these four action areas, may shift food systems towards more sustainable, inclusive, healthy and climate-resilient futures. These actions, summarised here, are presented in extended form in a report of an international initiative involving hundreds of stakeholders for reconfiguring food systems

    Mainstreaming gender and social differentiation into CCAFS research activities in West Africa: lessons learned and perspectives

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    This Info Note aims to present a summary of results from gender-related activities at the CSVs in West Africa. The gender mainstreaming included the capacity building of implementation team, the empowerment of women with gender sensitive activities and the understanding of gender perception on climate change and adaptation strategies
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