300 research outputs found
Sea surface temperature changes in the southern California borderlands during the last glacial-interglacial cycle
A variety of evidence suggests that average sea surface temperatures (SSTs) during the last glacial maximum in the California Borderlands region were significantly colder than during the Holocene. Planktonic foraminiferal δ18O evidence and average SST estimates derived by the modern analog technique indicate that temperatures were 6°-10°C cooler during the last glacial relative to the present. The glacial plankton assemblage is dominated by the planktonic foraminifer Neogloboquadrina pachyderma (sinistral coiling) and the coccolith Coccolithus pelagicus, both of which are currently restricted to subpolar regions of the North Pacific. The glacial-interglacial average SST change determined in this study is considerably larger than the 2°C change estimated by Climate: Long-Range Investigation, Mapping, and Prediction (CLIMAP) [1981]. We propose that a strengthened California Current flow was associated with the advance of subpolar surface waters into the Borderlands region during the last glacial
Statistical properties of near‐surface flow in the California coastal transition zone
The article of record as published may be found at https://doi.org/10.1029/91JC01072During the summers of 1987 and 1988, 77 near-surface satellite-tracked drifters were deployed in or near cold filaments near Point Arena, California (39°N), and tracked for up to 6 months as part of the Coastal Transition Zone (CTZ) program. The drifters had large drogues centered at 15 m, and the resulting drifter trajectory data set has been analyzed in terms of its Eulerian and Lagrangian statistics. The CTZ drifter results show that the California Current can be characterized in summer and fall as a meandering coherent jet which on average flows southward to at least 30°N, the southern end of the study domain. From 39°N south to about 33°N, the typical core velocities are of O(50 cm s−1) and the current meanders have alongshore wavelengths of O (300 km) and onshore-offshore amplitude of O(100–200 km). The lateral movement of this jet leads to large eddy kinetic energies and large eddy diffusivities, especially north of 36°N. The initial onshore-offshore component of diffusivity is always greater than the alongshore component in the study domain, but at the southern end, the eddy diffusivity is more isotropic, with scalar single particle diffusivity (Kxx + Kyy) of O(8 × 107 cm2 s−1). The eddy diffusivity increases with increasing eddy energy. Finally, a simple volume budget for the 1988 filament observed near 37°N off Point Arena suggests that subduction can occur in a filament at an average rate of O (10 m d−1) some 200 km offshore, thus allowing the cold water initially in the filament core to sink below the warmer ambient water by the time the surface velocity core has turned back onshore. This process explains why satellite temperature and color imagery tend to “see” only flow proceeding offshore
Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment.
Computational Approaches and Analysis for a Spatio-Structural-Temporal Invasive Carcinoma Model
Spatio-temporal models have long been used to describe biological systems of cancer, but it has not been until very recently that increased attention has been paid to structural dynamics of the interaction between cancer populations and the molecular mechanisms associated with local invasion. One system that is of particular interest is that of the urokinase plasminogen activator (uPA) wherein uPA binds uPA receptors on the cancer cell surface, allowing plasminogen to be cleaved into plasmin, which degrades the extracellular matrix and this way leads to enhanced cancer cell migration. In this paper, we develop a novel numerical approach and associated analysis for spatio-structuro-temporal modelling of the uPA system for up to two-spatial and two-structural dimensions. This is accompanied by analytical exploration of the numerical techniques used in simulating this system, with special consideration being given to the proof of stability within numerical regimes encapsulating a central differences approach to approximating numerical gradients. The stability analysis performed here reveals instabilities induced by the coupling of the structural binding and proliferative processes. The numerical results expound how the uPA system aids the tumour in invading the local stroma, whilst the inhibitor to this system may impede this behaviour and encourage a more sporadic pattern of invasion.PostprintPeer reviewe
Recommended from our members
Mixing of chlorophyll from the Middle Atlantic Bight cold pool into the Gulf Stream at Cape Hatteras in July 1993
In July 1993 we collected hydrographic data and information on chlorophyll distribution on the continental shelf north of Cape Hatteras and across the shelf break at Cape Hatteras. The data show that a warm, transparent mixed layer lies over much colder, euphotic, chlorophyll-rich bottom water on the shelf. This layer has temperature and salinity properties characteristic of the Middle Atlantic Bight (MAB) cold pool, a distinctive mass of cold bottom water formed when cold water from the Gulf of Maine and Scotian Shelf is isolated from surface water by vernal warming and seasonal stratification [Houghton et al., 1982]. The constant density of this chlorophyll-rich water (σФ = 25.0–25.6) combined with a strong chlorophyll gradient along the 25 σФ isopycnal at the shelf break indicates that chlorophyll advected off the shelf at Cape Hatteras in July 1993. TS diagrams further indicate that cold pool water, and the chlorophyll it contained, mixed into upper levels of the Gulf Stream. Thus the MAB may contribute to the nutrient budget of Atlantic surface waters through a long loop of circulation that transports deep water from the Labrador Sea to Cape Hatteras
Recommended from our members
Physical oceanographic observations off the Oregon coast, 1975 : WISP and UP-75
This report presents observations from two programs in 1975, WISP and UP-75 to study circulation off Oregon. WISP was a study of the transition between the winter and spring regimes, and UP-75 was designed to determine whether there is a poleward undercurrent along the continental slope during the upwellinq season. During WISP, eleven current meters were moored in three arrays across the shelf at 45°N from late January to late April, and hydrographic sections were made at intervals of several weeks from late January to mid-May. All current meters successfully measured velocity and
temperature; ten also measured conductivity. During UP-75, four current meters were moored in an array over the shelf, at the 100 m isobath,and six current meters were moored over the upper slope, at about the 500 m isobath, from late April to late July 1975; all measured velocity and temperature, and four also measured conductivity. At the end of July, there was a hydrographic section across the shelf, both moorings were recovered, and the inshore mooring was replaced with three current meters which were retrieved in September. This data report presents the hourly data from the current
meters, including time series of salinity and sigma-t; the hydrographic data; and low frequency time series (with periods longer than one day) of wind, adjusted sea level and the parameters measured from the current meters
Structured models of cell migration incorporating molecular binding processes
The dynamic interplay between collective cell movement and the various
molecules involved in the accompanying cell signalling mechanisms plays a
crucial role in many biological processes including normal tissue development
and pathological scenarios such as wound healing and cancer. Information about
the various structures embedded within these processes allows a detailed
exploration of the binding of molecular species to cell-surface receptors
within the evolving cell population. In this paper we establish a general
spatio-temporal-structural framework that enables the description of molecular
binding to cell membranes coupled with the cell population dynamics. We first
provide a general theoretical description for this approach and then illustrate
it with two examples arising from cancer invasion
Perspective article: Actions to reconfigure food systems
There is broad agreement that current food systems are not on a sustainable trajectory that will enable us to reach the Sustainable Development Goals by 2030, particularly in the face of anthropogenic climate change. Guided by a consideration of some food system reconfigurations in the past, we outline an agenda of work around four action areas: rerouting old systems into new trajectories; reducing risks; minimising the environmental footprint of food systems; and realigning the enablers of change needed to make new food systems function. Here we highlight food systems levers that, along with activities within these four action areas, may shift food systems towards more sustainable, inclusive, healthy and climate-resilient futures. These actions, summarised here, are presented in extended form in a report of an international initiative involving hundreds of stakeholders for reconfiguring food systems
Characteristic patterns of shelf circulation at the boundary between central and southern California
Mainstreaming gender and social differentiation into CCAFS research activities in West Africa: lessons learned and perspectives
This Info Note aims to present a summary of results from gender-related activities at the CSVs in West Africa. The gender mainstreaming included the capacity building of implementation team, the empowerment of women with gender sensitive activities and the understanding of gender perception on climate change and adaptation strategies
- …
