Diffusion of active tracers in fluctuating fields

The problem of a particle diffusion in a fluctuating scalar field is studied. In contrast to most studies of advection diffusion in random fields we analyze the case where the particle position is also coupled to the dynamics of the field. Physical realizations of this problem are numerous and range from the diffusion of proteins in fluctuating membranes and the diffusion of localized magnetic fields in spin systems. We present exact results for the diffusion constant of particles diffusing in dynamical Gaussian fields in the adiabatic limit where the field evolution is much faster than the particle diffusion. In addition we compute the diffusion constant perturbatively, in the weak coupling limit where the interaction of the particle with the field is small, using a Kubo-type relation. Finally we construct a simple toy model which can be solved exactly.Comment: 13 pages, 1 figur

A New Phase of Tethered Membranes: Tubules

We show that fluctuating tethered membranes with {\it any} intrinsic anisotropy unavoidably exhibit a new phase between the previously predicted ``flat'' and ``crumpled'' phases, in high spatial dimensions $d$ where the crumpled phase exists. In this new "tubule" phase, the membrane is crumpled in one direction but extended nearly straight in the other. Its average thickness is $R_G\sim L^{\nu_t}$ with $L$ the intrinsic size of the membrane. This phase is more likely to persist down to $d=3$ than the crumpled phase. In Flory theory, the universal exponent $\nu_t=3/4$, which we conjecture is an exact result. We study the elasticity and fluctuations of the tubule state, and the transitions into it.Comment: 4 pages, self-unpacking uuencoded compressed postscript file with figures already inside text; unpacking instructions are at the top of file. To appear in Phys. Rev. Lett. November (1995

Fluctuation induced interactions between domains in membranes

We study a model lipid bilayer composed of a mixture of two incompatible lipid types which have a natural tendency to segregate in the absence of membrane fluctuations. The membrane is mechanically characterized by a local bending rigidity $\kappa(\phi)$ which varies with the average local lipid composition $\phi$. We show, in the case where $\kappa$ varies weakly with $\phi$, that the effective interaction between lipids of the same type can either be everywhere attractive or can have a repulsive component at intermediate distances greater than the typical lipid size. When this interaction has a repulsive component, it can prevent macro-phase separation and lead to separation in mesophases with a finite domain size. This effect could be relevant to certain experimental and numerical observations of mesoscopic domains in such systems.Comment: 9 pages RevTex, 1 eps figur

Interactions between proteins bound to biomembranes

We study a physical model for the interaction between general inclusions bound to fluid membranes that possess finite tension, as well as the usual bending rigidity. We are motivated by an interest in proteins bound to cell membranes that apply forces to these membranes, due to either entropic or direct chemical interactions. We find an exact analytic solution for the repulsive interaction between two similar circularly symmetric inclusions. This repulsion extends over length scales of order tens of nanometers, and contrasts with the membrane-mediated contact attraction for similar inclusions on tensionless membranes. For non circularly symmetric inclusions we study the small, algebraically long-ranged, attractive contribution to the force that arises. We discuss the relevance of our results to biological phenomena, such as the budding of caveolae from cell membranes and the striations that are observed on their coats.Comment: 22 pages, 2 figure

Fluctuations of Fluctuation-Induced "Casimir" Forces

The force experienced by objects embedded in a correlated medium undergoing thermal fluctuations--the so-called fluctuation--induced force--is actually itself a fluctuating quantity. We compute the corresponding probability distribution and show that it is a Gaussian centered on the well-known Casimir force, with a non-universal standard deviation that can be typically as large as the mean force itself. The relevance of these results to the experimental measurement of fluctuation-induced forces is discussed, as well as the influence of the finite temporal resolution of the measuring apparatus.Comment: 4 pages, 2 figure

Engineered single- and multi-cell chemotaxis pathways in E. coli

We have engineered the chemotaxis system of Escherichia coli to respond to molecules that are not attractants for wild-type cells. The system depends on an artificially introduced enzymatic activity that converts the target molecule into a ligand for an E. coli chemoreceptor, thereby enabling the cells to respond to the new attractant. Two systems were designed, and both showed robust chemotactic responses in semisolid and liquid media. The first incorporates an asparaginase enzyme and the native E. coli aspartate receptor to produce a response to asparagine; the second uses penicillin acylase and an engineered chemoreceptor for phenylacetic acid to produce a response to phenylacetyl glycine. In addition, by taking advantage of a ‘hitchhiker' effect in which cells producing the ligand can induce chemotaxis of neighboring cells lacking enzymatic activity, we were able to design a more complex system that functions as a simple microbial consortium. The result effectively introduces a logical ‘AND' into the system so that the population only swims towards the combined gradients of two attractants

Genus Zero Correlation Functions in c<1 String Theory

We compute N-point correlation functions of pure vertex operator states(DK states) for minimal models coupled to gravity. We obtain agreement with the matrix model results on analytically continuing in the numbers of cosmological constant operators and matter screening operators. We illustrate this for the cases of the $(2k-1,2)$ and $(p+1,p)$ models.Comment: 11 pages, LaTeX, IMSc--92/35. (revised) minor changes plus one reference adde

Non-linear Structures in Non-critical NSR String

We investigate the Ward identities of the \W_{\infty} symmetry in the super-Liouville theory coupled to the super-conformal matter of central charge ${\hat c}_M = 1-2(p-q)^2 /pq$. The theory is classified into two chiralities. For the positive chirality, all gravitationally dressed scaling operators are generated from the $q-1$ gravitational primaries by acting one of the ring generators in the R-sector on them repeatedly. After fixing the normalizations of the dressed scaling operators, we find that the Ward identities are expressed in the form of the {\it usual} \W_q algebra constraints as in the bosonic case: \W^{(k+1)}_n \tau =0, $(k=1,\cdots,q-1 ;~ n \in {\bf Z}_{\geq 1-k})$, where the equations for even and odd $n$ come from the currents in the NS- and the R-sector respectively. The non-linear terms come from the anomalous contributions at the boundaries of moduli space. The negative chirality is defined by interchanging the roles of $p$ and $q$. Then we get the \W_p algebra constraints.Comment: 22 pages, Latex file, YITP/U-94-16, UT-Komaba/94-1

On the amplitudes for non-critical n=2 supuerstrings

We compute correlation functions in $N=2$ non critical superstrings on the sphere. Our calculations are restrained to the ($s=0$) bulk amplitudes. We show that the four point function factorizes as a consequence of the non-critical kinematics, but differently from the $N=0,1$ cases no extra discrete state appears in the $\hat c\to 1^-$ limit.Comment: 10 page