Concurrent Bilateral Emphysematous Pyelonephritis and Emphysematous Cystitis: A Case Report of Glomerulonephritis Severe Complication

Michał Godzisz, Przemysław Mitura, Damian Widz, Damian Sudoł, Iga Kuliniec, Krzysztof Bar Department of Urology and Urologic Oncology, Medical University of Lublin, Lublin, PolandCorrespondence: Michał GodziszMedical University of Lublin, Jaczewskiego 8, 20-954 Lublin, 20-819, PolandTel +48660346267Email [email protected]: Emphysematous pyelonephritis (EPN) and emphysematous cystitis (EC) are severe, necrotizing emphysematous urinary tract infections (EUTI) characterized by the presence of gas in the lumen and wall of the urinary tract and renal parenchyma. EUTIs are quite uncommon, but combination of bilateral EPN and EC is extremely rare. We report a case of 57-year-old diabetic female diagnosed with septic shock due to concurrent bilateral EPN and EC. Patient was successfully treated with a drainage of pelvicalyceal systems and the bladder combined with a conservative approach. This unique case presents a possible association between glomerulonephritis and EUTI.Keywords: emphysematous pyelonephritis, emphysematous cystitis, glomerulonephritis, diabetes, septic shock, urinary tract infection

Badania stanu wybranych osuwisk na terenie Kadzielni

The Kadzielnia nature reserve located in Kielce is a remnant of the long-term exploitation of limestone. The slopes of a former quarry are unstable; landslide processes occur there, posing a threat to humans and disturbing the landscape. This condition requires observation of the changes in order to take preventive measures. The article presents the preliminary results of such observations, performed for four selected landslides in Kadzielnia. While measuring, modern geodetic techniques were applied, including satellite technology, scanning tacheometry and laser scanning. Obtained results indicate slight displacements of the monitored walls over several months. Observations which were made are initiating study on the behavior of the landslides in the area of Kadzielnia, aimed at early detection of threats and enabling taking safety procedures

Characterization of new cocrystals by raman spectroscopy, powder X-ray diffraction, differential scanning calorimetry, and transmission raman spectroscopy

Cocrystals have been increasingly recognized as an attractive alternative delivery form for solids of drug products. In this work, salicylic acid was employed as a cocrystal former with the nicotinic acid, dl-phenylalanine, and 6-hydroxynicotinic acid (6HNA). Also, 3,4-dihydroxybenzoic acid with oxalic acid was studied. The cocrystals in all cases were prepared by slow evaporation from ethanol followed by characterization using Raman spectroscopy, powder X-ray diffraction, transmission Raman spectroscopy (TRS), and differential scanning calorimetry. Full understanding of the effects of formation on the vibrational modes of motion was obtained by the complete assignment of the spectra of the starting materials and of the cocrystal components. The results show that all the cocrystals, prepared in a 1:1 molar ratio, possess unique thermal, spectroscopic, and X-ray diffraction properties. Raman and TRS spectra showed that the vibrational modes of the cocrystal were different from those of the starting materials, suggesting that Raman spectroscopy and TRS are effective tools to evaluate cocrystal formation through interaction of their components. In addition, we have used a synthetic standard containing a 1:1:1 mixture of KNO 3 and raw material for which each sample was analyzed at seven random positions, with each point sampled twice. We have done the same with all cocrystals (1:1 KNO 3 and cocrystal), the ratios confirming that the cocrystal components (were in a 1:1 molar ratio). © 2010 American Chemical Society