9,794 research outputs found
Rocketdyne's advanced coal slurry pumping program
The Rocketdyne Division of Rockwell International Corporation is conducting a program for the engineering, fabrication, and testing of an experimental/prototype high-capacity, high-pressure centrifugal slurry feed pump for coal liquefaction purposes. The abrasion problems in a centrifugal slurry pump are primarily due to the manner in which the hard, solid particles contained in the slurry are transported through the hydraulic flow passages within the pump. The abrasive particles can create scraping, grinding, cutting, and sandblasting effects on the various exposed parts of the pump. These critical areas involving abrasion and impact erosion wear problems in a centrifugal pump are being addressed by Rocketdyne. The mechanisms of abrasion and erosion are being studied through hydrodynamic analysis, materials evaluation, and advanced design concepts
Operational and research aspects of a radio-controlled model flight test program
The operational and research aspects of a subscale, radio-controlled model flight test program are presented. By using low-cost free-flying models, an approach was developed for obtaining research-quality vehicle performance and aerodynamic information. The advantages and limitations learned by applying this approach to a specific flight test program are described. The research quality of the data acquired shows that model flight testing is practical for obtaining consistent and repeatable flight data
Further Studies on Fire Retardant Polystyrene by Friedel–Crafts Chemistry
The combination of a copolymer of 4-vinylbenzyl alcohol and styrene with 2-ethylhexyldiphenylphosphate (DPP) and with metal chlorides has been studied by TGA, radiative gasification, Cone Calorimetry, and oxygen index measurements. Evidence is presented in support of a cross-linking reaction with the additives and the copolymer, which proceeds through a Friedel–Crafts mechanism. This approach reduces the peak heat release rate (HRR) by 60% as measured in the Cone Calorimeter. There is a significant reduction in the mass loss rate during the thermal degradation, and evidence of char formation is observed in the radiative gasification experiments
Discriminating active from latent tuberculosis in patients presenting to community clinics.
BACKGROUND: Because of the high global prevalence of latent TB infection (LTBI), a key challenge in endemic settings is distinguishing patients with active TB from patients with overlapping clinical symptoms without active TB but with co-existing LTBI. Current methods are insufficiently accurate. Plasma proteomic fingerprinting can resolve this difficulty by providing a molecular snapshot defining disease state that can be used to develop point-of-care diagnostics. METHODS: Plasma and clinical data were obtained prospectively from patients attending community TB clinics in Peru and from household contacts. Plasma was subjected to high-throughput proteomic profiling by mass spectrometry. Statistical pattern recognition methods were used to define mass spectral patterns that distinguished patients with active TB from symptomatic controls with or without LTBI. RESULTS: 156 patients with active TB and 110 symptomatic controls (patients with respiratory symptoms without active TB) were investigated. Active TB patients were distinguishable from undifferentiated symptomatic controls with accuracy of 87% (sensitivity 84%, specificity 90%), from symptomatic controls with LTBI (accuracy of 87%, sensitivity 89%, specificity 82%) and from symptomatic controls without LTBI (accuracy 90%, sensitivity 90%, specificity 92%). CONCLUSIONS: We show that active TB can be distinguished accurately from LTBI in symptomatic clinic attenders using a plasma proteomic fingerprint. Translation of biomarkers derived from this study into a robust and affordable point-of-care format will have significant implications for recognition and control of active TB in high prevalence settings
Effect of thermal exposure, forming, and welding on high-temperature, dispersion-strengthened aluminum alloy: Al-8Fe-1V-2Si
The feasibility of applying conventional hot forming and welding methods to high temperature aluminum alloy, Al-8Fe-1V-2Si (FVS812), for structural applications and the effect of thermal exposure on mechanical properties were determined. FVS812 (AA8009) sheet exhibited good hot forming and resistance welding characteristics. It was brake formed to 90 deg bends (0.5T bend radius) at temperatures greater than or equal to 390 C (730 F), indicating the feasibility of fabricating basic shapes, such as angles and zees. Hot forming of simple contoured-flanged parts was demonstrated. Resistance spot welds with good static and fatigue strength at room and elevated temperatures were readily produced. Extended vacuum degassing during billet fabrication reduced porosity in fusion and resistance welds. However, electron beam welding was not possible because of extreme degassing during welding, and gas-tungsten-arc welds were not acceptable because of severely degraded mechanical properties. The FVS812 alloy exhibited excellent high temperature strength stability after thermal exposures up to 315 C (600 F) for 1000 h. Extended billet degassing appeared to generally improve tensile ductility, fatigue strength, and notch toughness. But the effects of billet degassing and thermal exposure on properties need to be further clarified. The manufacture of zee-stiffened, riveted, and resistance-spot-welded compression panels was demonstrated
G protein beta gamma subunits synthesized in Sf9 cells. Functional characterization and the significance of prenylation of gamma
Heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) consist of a nucleotide-binding alpha subunit and a high- affinity complex of beta and gamma subunits. There is molecular heterogeneity of beta and gamma, but the significance of this diversity is poorly understood. Different G protein beta and gamma subunits have been expressed both singly and in combinations in Sf9 cells. Although expression of individual subunits is achieved in all cases, beta gamma subunit activity (support of pertussis toxin-catalyzed ADP-ribosylation of rGi alpha 1) is detected only when beta and gamma are expressed concurrently. Of the six combinations of beta gamma tested (beta 1 or beta 2 with gamma 1, gamma 2, or gamma 3), only one, beta 2 gamma 1, failed to generate a functional complex. Each of the other five complexes has been purified by subunit exchange chromatography using Go alpha-agarose as the chromatographic matrix. We have detected differences in the abilities of the purified proteins to support ADP- ribosylation of Gi alpha 1; these differences are attributable to the gamma component of the complex. When assayed for their ability to inhibit calmodulin-stimulated type-I adenylylcyclase activity or to potentiate Gs alpha-stimulated type-II adenylylcyclase, recombinant beta 1 gamma 1 and transducin beta gamma are approximately 10 and 20 times less potent, respectively, than the other complexes examined. Prenylation and/or further carboxyl-terminal processing of gamma are not required for assembly of the beta gamma subunit complex but are indispensable for high affinity interactions of beta gamma with either G protein alpha subunits or adenylylcyclases
One Spin Trace Formalism for
It has been known for some time that there are two methods to calculate with staggered fermions: one is the two spin trace formalism and the other is
the one spin trace formalism. Until now, the two spin trace formalism has been
exclusively used for weak matrix element calculations with staggered fermions.
Here, the one spin trace formalism to calculate with staggered fermions
is explained. It is shown that the one spin trace operators require additional
chiral partner operators in order to keep the continuum chiral behavior. The
renormalization of the one spin trace operators is described and compared with
the two spin trace formalism.Comment: 47 pages, latex, 4 figures are available on reques
Flavor Changing Neutral Currents in a Realistic Composite Technicolor Model
We consider the phenomenology of a composite technicolor model proposed
recently by Georgi. Composite technicolor interactions produce four-quark
operators in the low energy theory that contribute to flavor changing neutral
current processes. While we expect operators of this type to be induced at the
compositeness scale by the flavor-symmetry breaking effects of the preon mass
matrices, the Georgi model also includes operators from higher scales that are
not GIM-suppressed. Since these operators are potentially large, we study their
impact on flavor changing neutral currents and CP violation in the neutral ,
, and meson systems.Comment: 16 pages, LaTeX + embedded PicTeX figures requiring prepictex,
pictex, and postpictex inputs. HUTP.STY include
Modular Structure and Duality in Conformal Quantum Field Theory
Making use of a recent result of Borchers, an algebraic version of the
Bisognano-Wichmann theorem is given for conformal quantum field theories, i.e.
the Tomita-Takesaki modular group associated with the von Neumann algebra of a
wedge region and the vacuum vector concides with the evolution given by the
rescaled pure Lorentz transformations preserving the wedge. A similar geometric
description is valid for the algebras associated with double cones. Moreover
essential duality holds on the Minkowski space , and Haag duality for double
cones holds provided the net of local algebras is extended to a pre-cosheaf on
the superworld , i.e. the universal covering of the Dirac-Weyl
compactification of . As a consequence a PCT symmetry exists for any
algebraic conformal field theory in even space-time dimension. Analogous
results hold for a Poincar\'e covariant theory provided the modular groups
corresponding to wedge algebras have the expected geometrical meaning and the
split property is satisfied. In particular the Poincar\'e representation is
unique in this case.Comment: 23 pages, plain TeX, TVM26-12-199
Chiral effective theory predictions for deuteron form factor ratios at low Q^2
We use chiral effective theory to predict the deuteron form factor ratio
G_C/G_Q as well as ratios of deuteron to nucleon form factors. These ratios are
calculated to next-to-next-to-leading order. At this order the chiral expansion
for the NN isoscalar charge operator (including consistently calculated 1/M
corrections) is a parameter-free prediction of the effective theory. Use of
this operator in conjunction with NLO and NNLO chiral effective theory wave
functions produces results that are consistent with extant experimental data
for Q^2 < 0.35 GeV^2. These wave functions predict a deuteron quadrupole moment
G_Q(Q^2=0)=0.278-0.282 fm^2-with the variation arising from short-distance
contributions to this quantity. The variation is of the same size as the
discrepancy between the theoretical result and the experimental value. This
motivates the renormalization of G_Q via a two-nucleon operator that couples to
quadrupole photons. After that renormalization we obtain a robust prediction
for the shape of G_C/G_Q at Q^2 < 0.3 GeV^2. This allows us to make precise,
model-independent predictions for the values of this ratio that will be
measured at the lower end of the kinematic range explored at BLAST. We also
present results for the ratio G_C/G_M.Comment: 31 pages, 7 figure
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