In Vivo Simulation of the Purulent Peritonitis

Currently, purulent-inflammatory diseases of the abdominal organs are the prevalent causes of complications and mortality. Treatment of these diseases complicated by peritonitis is one of the urgent problems in modern clinical medicine. Experiment is important for testing new treatment methods. This article provides a systematic analysis of the current in vivo models of the purulent peritonitis, which are used to test the options for surgical treatment and combinations of antibacterial drugs. We describe the most common models as well as rare simulations of specific peritonitis. It should be noted that despite the wide use of minimally invasive techniques, the literature has few reports on simulation of peritonitis through the laparoscopic approach

A mixed integer programming model for long term capacity expansion planning: A case study from The Hunter Valley Coal Chain

The Hunter Valley Coal Chain is the largest coal export operation in the world with a throughput in excess of 100 million tonnes per annum (Mtpa). Coal is delivered to the shipping terminal from 40 mines using 27 coal load points spread across the Hunter Valley region. This paper describes an MILP model for determining the capacity requirements, and the most cost effective capacity improvement initiatives, to meet demand while minimising the total cost of infrastructure and demurrage. We present results from computational experiments on the model's performance along with a comparison of the model's output with detailed analyses by the coal chain analysts and planners