Ten golden rules for optimal antibiotic use in hospital settings: the WARNING call to action

Antibiotics are recognized widely for their benefits when used appropriately. However, they are often used inappropriately despite the importance of responsible use within good clinical practice. Effective antibiotic treatment is an essential component of universal healthcare, and it is a global responsibility to ensure appropriate use. Currently, pharmaceutical companies have little incentive to develop new antibiotics due to scientific, regulatory, and financial barriers, further emphasizing the importance of appropriate antibiotic use. To address this issue, the Global Alliance for Infections in Surgery established an international multidisciplinary task force of 295 experts from 115 countries with different backgrounds. The task force developed a position statement called WARNING (Worldwide Antimicrobial Resistance National/International Network Group) aimed at raising awareness of antimicrobial resistance and improving antibiotic prescribing practices worldwide. The statement outlined is 10 axioms, or “golden rules,” for the appropriate use of antibiotics that all healthcare workers should consistently adhere in clinical practice

Aspects of expert system of engineering management of technical condition of grain harvesters

Engineering management of the technical condition of combine harvesters is mainly entrusted to the combine operator or service team, for which the greatest difficulty is related to information and intellectual aspects, which determine the high requirements for operator qualification, to the level of technical diagnostic tools. The solution of manually littlestudied and complex problems of technical diagnostics of combine harvesters encounters natural difficulties associated with the need for heuristic processing of large amounts of information and logical analysis of complex interconnected processes. The value of these factors is exacerbated by the rapidity of the harvesting process, the high risk of erroneous or delayed assessment of the technical condition of the combine, which leads to significant crop losses and does not allow to obtain a possible effect. Thus, ensuring high quality maintenance of the combine harvester largely depends on the professional competence of staff, which is a deep knowledge of the design of the machine and its subsystems: mechanical systems, hydraulics, electrical equipmen

Modeling techniques for kinematic analysis of a six-axis robotic arm

The purpose of this analysis is to evaluate the effectiveness of different modeling techniques for a COMAU six-axis robot arm. The robot manipulator represents one of the most used robots in the mechanical industry. For robots, with a high number of degrees of freedom, to obtain a kinematic model, Denavit-Hartemberg parameters allow representing geometric transformations in the Euclidean space through the minimum number of parameters. Furthermore, the use of detailed multibody models and the use of sophisticated tools like the Robotics Toolbox System, allow performing, in a very efficient way, inverse kinematic analysis and trajectory planning to control the robot move from one configuration to another