Feasibility study of resistance welding of aluminum alloys, stainless steel, and titanium in a hard vacuum Final report, Jun. 27, 1967 - Feb. 29, 1968

Tensile strength and X ray analysis of resistance spot welded aluminum and stainless steel alloy

Welding of commercial base plates is investigated

Investigation of aluminum alloy welds reveals that the combinations of metallic elements with hydrogen are not capable of producing weld porosity themselves, rather they tend to increase the amount of porosity only in the presence of arc contamination by water vapor

Boston City Hospital

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An Energy Feedback System for the MIT/Bates Linear Accelerator

We report the development and implementation of an energy feedback system for the MIT/Bates Linear Accelerator Center. General requirements of the system are described, as are the specific requirements, features, and components of the system unique to its implementation at the Bates Laboratory. We demonstrate that with the system in operation, energy fluctuations correlated with the 60 Hz line voltage and with drifts of thermal origin are reduced by an order of magnitude

Welding-base metal investigation Final report, 27 Jun. 1964 - 28 Jul. 1965

Weld defects associated with aluminum alloys - monitoring weld shielding gas purit

A Sweet Home No More?: The Future for Habitat Protection Under the Endangered Species Act

20 pages. Includes bibliographical references and biographical information for Federico Cheever and Murray D. Feldman. Contents: Babbitt v. Sweet Home Chapter of Communities for a Greater Oregon / Federico Cheever -- The Sweet Home decision and private property issues / Murray D. Feldman -- Memorandum of Agreement between the State of Colorado and the Department of the Interior concerning programs to manage Colorado\u27s declining native species The U.S. Supreme Court decision in Babbitt v. Sweet Home Chapter of Communities for a Great Oregon,115 S.Ct. 2407 (1995), held that the Department of the Interior reasonably construed Congress\u27 intent when it included habitat modification that injures protected wildlife within the definition of harm prohibited by the Endangered Species Act. Speakers include Professor Federico Cheever, University of Denver College of Law; Paul Seby, attorney with the Mountain States Legal Foundation; and Paul Gertler, Assistant Regional Director, U.S. Fish and Wildlife Service. Center Director Betsy Rieke will moderate

Regulation and Function of the Interleukin 13 Receptor α 2 During a T Helper Cell Type 2–dominant Immune Response

Highly polarized type 2 cytokine responses can be harmful and even lethal to the host if they are too vigorous or persist too long. Therefore, it is important to elucidate the mechanisms that down-regulate these reactions. Interleukin (IL)-13 has emerged as a central mediator of T helper cell (Th)2-dominant immune responses, exhibiting a diverse array of functional activities including regulation of airway hyperreactivity, resistance to nematode parasites, and tissue remodeling and fibrosis. Here, we show that IL-13 receptor (R)α2 is a critical down-regulatory factor of IL-13–mediated tissue fibrosis induced by the parasitic helminth Schistosoma mansoni. IL-13Rα2 expression was induced after the onset of the fibrotic response, IL-10, IL-13, and Stat6 dependent, and inhibited by the Th1-inducing adjuvant IL-12. Strikingly, schistosome-infected C57BL/6 and BALB/c IL-13Rα2–deficient mice showed a marked exacerbation in hepatic fibrosis, despite displaying no change in granuloma size, tissue eosinophilia, or mastocytosis. Fibrosis increased despite the fact that IL-13 levels decreased significantly in the liver and serum. Importantly, pathology was prevented when IL-13Rα2–deficient mice were treated with a soluble IL-13Rα2-Fc construct, formally demonstrating that their exacerbated fibrotic response was due to heightened IL-13 activity. Together, these studies illustrate the central role played by the IL-13Rα2 in the down-regulation of a chronic and pathogenic Th2-mediated immune response