14,601 research outputs found

    Analyzing Operating and Support Costs for Air Force Aircraft

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    Purpose: Recent legislation resulted in an elevation of operating and support (O&S) costs’ relative importance for decision-making in Department of Defense programs. However, a lack of research in O&S hinders a cost analyst’s abilities to provide accurate sustainment estimates. Thus, the purpose of this paper is to investigate when Air Force aircraft O&S costs stabilize and to what degree. Next, a parametric O&S model is developed to predict median O&S costs for use as a new tool for cost analyst practitioners.Design/Methodology/Approach: Utilizing the Air Force total ownership cost database, 44 programs consisting of 765 observations from 1996 to 2016 are analyzed. First, stability is examined in three areas: total O&S costs, the six O&S cost element structures and by aircraft type. Next, stepwise regression is used to predict median O&S costs per total active inventory (CPTAI) and identify influential variables.Findings: Stability results vary by category but generally are found to occur approximately five years from initial operating capability. The regression model explains 89.01 per cent of the variance in the data set when predicting median O&S CPTAI. Aircraft type, location of lead logistics center and unit cost are the three largest contributing factors

    Delineating Operating and Support Costs in Aircraft Platforms

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    As the costs of Department of Defense (DoD) Weapon Systems increase, the ability to estimate the Operating and Support (O&S) costs accurately for the various weapon systems has become vital to long-term affordability. This research focuses on the O&S costs of the Air Force fixed-wing arsenal (i.e., platforms) for 1996–2016. First, the Cost Element Structure (CES) for 52 aircraft platforms and seven operational mission categories is analyzed to derive the descriptive statistics per aircraft category through examination of actual historical costs. Second, testing to identify statistical differences within the O&S CES construct across various Air Force aircraft categories is conducted. DoD cost estimators and stakeholders alike can benefit from this research by utilizing the results as cross-checks for predicting O&S costs through analogous-based estimates and as an in-depth analysis into categories of CES costs being incurred

    Issues in joint SZ and optical cluster finding

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    We apply simple optical and SZ cluster finders to mock galaxy catalogues and SZ flux maps created from dark matter halos in a (1 Gpc/h)^3 dark matter simulation, at redshifts 0.5 and 0.9. At each redshift, the two catalogues are then combined to assess how well they can improve each other, and compared to several variants of catalogues made using SZ flux and galaxy information simultaneously. We use several different criteria to compare the catalogues, and illustrate some of the tradeoffs which arise in tuning the galaxy cluster finders with respect to these criteria. We detail many of the resulting improvements and issues which arise in comparing and combining these two types of data sets.Comment: 14 pages, added information thanks to helpful suggestions from refere

    Modelling predictors of molecular response to frontline imatinib for patients with chronic myeloid leukaemia

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    BACKGROUND: Treatment of patients with chronic myeloid leukaemia (CML) has become increasingly difficult in recent years due to the variety of treatment options available and challenge deciding on the most appropriate treatment strategy for an individual patient. To facilitate the treatment strategy decision, disease assessment should involve molecular response to initial treatment for an individual patient. Patients predicted not to achieve major molecular response (MMR) at 24 months to frontline imatinib may be better treated with alternative frontline therapies, such as nilotinib or dasatinib. The aims of this study were to i) understand the clinical prediction 'rules' for predicting MMR at 24 months for CML patients treated with imatinib using clinical, molecular, and cell count observations (predictive factors collected at diagnosis and categorised based on available knowledge) and ii) develop a predictive model for CML treatment management. This predictive model was developed, based on CML patients undergoing imatinib therapy enrolled in the TIDEL II clinical trial with an experimentally identified achieving MMR group and non-achieving MMR group, by addressing the challenge as a machine learning problem. The recommended model was validated externally using an independent data set from King Faisal Specialist Hospital and Research Centre, Saudi Arabia. PRINCIPLE FINDINGS: The common prognostic scores yielded similar sensitivity performance in testing and validation datasets and are therefore good predictors of the positive group. The G-mean and F-score values in our models outperformed the common prognostic scores in testing and validation datasets and are therefore good predictors for both the positive and negative groups. Furthermore, a high PPV above 65% indicated that our models are appropriate for making decisions at diagnosis and pre-therapy. Study limitations include that prior knowledge may change based on varying expert opinions; hence, representing the category boundaries of each predictive factor could dramatically change performance of the models.Haneen Banjar, Damith Ranasinghe, Fred Brown, David Adelson, Trent Kroger, Tamara Leclercq, Deborah White, Timothy Hughes, Naeem Chaudhr

    DEM study of particle scale effect on plain and rotary jacked pile behaviour in granular materials

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    The capacity of open-ended piles strongly depends on the potential plugging occurring during installation. The Discrete Element Method (DEM) is particularly suitable to the study of pile plugging, as it can model large soil deformation. However, DEM simulation of the 3D boundary value problems is computationally expensive, and particle upscaling is usually used to reduce the number of particles modelled. In this paper, two granular beds were created with the same average porosity, initial stress field and contact parameters, but different particle scales. Two pile geometries were installed by plain and rotary jacking. Normalised results show that the pile penetration mechanism is strongly affected by the particle scale. Larger particles lead to earlier pile plugging, higher shaft resistance and require a greater force to penetrate the ground. This effect can be linked to a modified penetration mechanism, with larger shear zones and less well defined “nose cone” under the pile tip for larger particles. Changing particle scaling has a neutral effect on the total penetration resistance of a rotary jacked pile, but reduces the base penetration and increases the plug resistance. Maximising the ratio of particle scale to wall thickness is key to adequately capturing the pile coring mechanism

    Red Galaxy Growth and the Halo Occupation Distribution

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    We have traced the past 7 Gyr of red galaxy stellar mass growth within dark matter halos. We have determined the halo occupation distribution, which describes how galaxies reside within dark matter halos, using the observed luminosity function and clustering of 40,696 0.2<z<1.0 red galaxies in Bootes. Half of 10^{11.9} Msun/h halos host a red central galaxy, and this fraction increases with increasing halo mass. We do not observe any evolution of the relationship between red galaxy stellar mass and host halo mass, although we expect both galaxy stellar masses and halo masses to evolve over cosmic time. We find that the stellar mass contained within the red population has doubled since z=1, with the stellar mass within red satellite galaxies tripling over this redshift range. In cluster mass halos most of the stellar mass resides within satellite galaxies and the intra-cluster light, with a minority of the stellar mass residing within central galaxies. The stellar masses of the most luminous red central galaxies are proportional to halo mass to the power of a third. We thus conclude that halo mergers do not always lead to rapid growth of central galaxies. While very massive halos often double in mass over the past 7 Gyr, the stellar masses of their central galaxies typically grow by only 30%.Comment: Accepted for publication in the ApJ. 34 pages, 22 Figures, 5 Table
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