1,301 research outputs found

    Promise, Potential, Opportunity: Successful HBCU Presidential Fundraising Strategies

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    With roots going back to the early 1830s and up to today, African-Americans continue to choose Historically Black College and Universities (HBCUs) for their post-secondary education needs. To understand the fundraising strategies utilized at HBCUs, this dissertation examines the efforts of a targeted group of HBCU presidents who have excelled in the philanthropic enterprise of fundraising for their institutions, achieving success in ways their fellow presidential peers have not. Due to a multitude of issues, HBCUs have historically been underfunded, and many are facing challenges from a resource development perspective. Because of this chronic issue, the area of fundraising strategies utilized at certain HBCUs is important to address. To gain greater insights, my multiple case study examined seven HBCU presidents, their fundraising strategies and approaches. My findings point to very consistent practices among the HBCU presidents interviewed. They each established a clear vision for their institutions and their fundraising priorities and were focused on getting their key constituents behind the vision. A few of the key themes which emerged involved the importance of developing and executing strategic organizational plans, based on research, data and metrics, and the importance of building effective internal and external relationships to advance HBCU fundraising programs. Overall, the findings from my study provide a clearer understanding of fundraising at HBCUs from the point of view of seven HBCU presidents. HBCUs are staple institutions of the higher education landscape, educating nearly one-third of all African-Americans in the U.S. (NCES, Fast Facts, 2019). Therefore, it is critical that these institutions continue to not only survive but thrive

    Chromosome replication: from ORC to fork

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    A report on the 2001 Eukaryotic DNA Replication meeting, Cold Spring Harbor Laboratory, New York, 5-9 September 2001

    Neuromuscular Taping Application in Counter Movement Jump: Biomechanical Insight in a Group of Healthy Basketball Players.

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    Kinesiologic elastic tape is widely used for both clinical and sport applications although its efficacy in enhancing agonistic performance is still controversial. Aim of the study was to verify in a group of healthy basketball players whether a neuromuscular taping application (NMT) on ankle and knee joints could affect the kinematic and the kinetic parameters of the jump, either by enhancing or inhibiting the functional performance. Fourteen healthy male basketball players without any ongoing pathologies at upper limbs, lower limbs and trunk volunteered in the study. They randomly performed 2 sets of 5 counter movement jumps (CMJ) with and without application of Kinesiologic tape. The best 3 jumps of each set were considered for the analysis. The Kinematics parameters analyzed were: knees maximal flexion and ankles maximal dorsiflexion during the push off phase, jump height and take off velocity. Vertical ground reaction force and maximal power expressed in the push off phase of the jump were also investigated. The NMT application in both knees and ankles showed no statistically significant differences in the kinematic and kinetic parameters and did not interfere with the CMJ performance. Bilateral NMT application in the group of healthy male basketball players did not change kinematics and kinetics jump parameters, thus suggesting that its routine use should have no negative effect on functional performance. Similarly, the combined application of the tape on both knees and ankles did not affect in either way jump performance

    Bod1, a novel kinetochore protein required for chromosome biorientation

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    We have combined the proteomic analysis of Xenopus laevis in vitro–assembled chromosomes with RNA interference and live cell imaging in HeLa cells to identify novel factors required for proper chromosome segregation. The first of these is Bod1, a protein conserved throughout metazoans that associates with a large macromolecular complex and localizes with kinetochores and spindle poles during mitosis. Small interfering RNA depletion of Bod1 in HeLa cells produces elongated mitotic spindles with severe biorientation defects. Bod1-depleted cells form syntelic attachments that can oscillate and generate enough force to separate sister kinetochores, suggesting that microtubule–kinetochore interactions were intact. Releasing Bod1-depleted cells from a monastrol block increases the frequency of syntelic attachments and the number of cells displaying biorientation defects. Bod1 depletion does not affect the activity or localization of Aurora B but does cause mislocalization of the microtubule depolymerase mitotic centromere- associated kinesin and prevents its efficient phosphorylation by Aurora B. Therefore, Bod1 is a novel kinetochore protein that is required for the detection or resolution of syntelic attachments in mitotic spindles

    Soliton switching using cascaded nonlinear-optical loop mirrors

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    We demonstrate multiple-peaked switching in a nonlinear-optical loop mirror and present an experimental investigation of device cascading in the soliton regime based on a sequence of two independent nonlinear-optical loop mirrors. Cascading leads to an enhanced switching response with sharper switching edges, flattened peaks, and increased interpeak extinction ratios. We observe that pulses emerging from the cascade retain the sech2 temporal profile of a soliton with minimal degradation in the spectral characteristics

    Spatiotemporal dispersion and wave envelopes with relativistic and pseudorelativistic characteristics

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    A generic nonparaxial model for pulse envelopes is presented. Classic Schro¨dinger-type descriptions of wave propagation have their origins in slowly-varying envelopes combined with a Galilean boost to the local time frame. By abandoning these two simplifications, a picture of pulse evolution emerges in which frame-of-reference considerations and space-time transformations take center stage. A wide range of effects, analogous to those in special relativity, then follows for both linear and nonlinear systems. Explicit demonstration is presented through exact bright and dark soliton pulse solutions

    Universal continuous-variable quantum computation: Requirement of optical nonlinearity for photon counting

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    Although universal continuous-variable quantum computation cannot be achieved via linear optics (including squeezing), homodyne detection and feed-forward, inclusion of ideal photon counting measurements overcomes this obstacle. These measurements are sometimes described by arrays of beam splitters to distribute the photons across several modes. We show that such a scheme cannot be used to implement ideal photon counting and that such measurements necessarily involve nonlinear evolution. However, this requirement of nonlinearity can be moved "off-line," thereby permitting universal continuous-variable quantum computation with linear optics.Comment: 6 pages, no figures, replaced with published versio

    Characteristics and stability of soliton crystals in optical fibres for the purpose of optical frequency comb generation

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    We study the properties of a soliton crystal, a bound state of several optical pulses that propagate with a fixed temporal separation through the optical fibres of the proposed approach for generation of optical frequency combs (OFC) for astronomical spectrograph calibration. This approach - also being suitable for subpicosecond pulse generation for other applications - consists of a conventional single-mode fibre and a suitably pumped Erbium-doped fibre. Two continuous-wave lasers are used as light source. The soliton crystal arises out of the initial deeply modulated laser field at low input powers; for higher input powers, it dissolves into free solitons. We study the soliton crystal build-up in the first fibre stage with respect to different fibre parameters (group-velocity dispersion, nonlinearity, and optical losses) and to the light source characteristics (laser frequency separation and intensity difference). We show that the soliton crystal can be described by two quantities, its fundamental frequency and the laser power-threshold at which the crystal dissolves into free solitons. The soliton crystal exhibits features of a linear and nonlinear optical pattern at the same time and is insensitive to the initial laser power fluctuations. We perform our studies using the numerical technique called Soliton Radiation Beat Analysis

    Full Quantum Analysis of Two-Photon Absorption Using Two-Photon Wavefunction: Comparison with One-Photon Absorption

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    For dissipation-free photon-photon interaction at the single photon level, we analyze one-photon transition and two-photon transition induced by photon pairs in three-level atoms using two-photon wavefunctions. We show that the two-photon absorption can be substantially enhanced by adjusting the time correlation of photon pairs. We study two typical cases: Gaussian wavefunction and rectangular wavefunction. In the latter, we find that under special conditions one-photon transition is completely suppressed while the high probability of two-photon transition is maintained.Comment: 6 pages, 4 figure
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