On the Supergravity Gauge theory Correspondence and the Matrix Model

We review the assumptions and the logic underlying the derivation of DLCQ Matrix models. In particular we try to clarify what remains valid at finite $N$, the role of the non-renormalization theorems and higher order terms in the supergravity expansion. The relation to Maldacena's conjecture is also discussed. In particular the compactification of the Matrix model on $T_3$ is compared to the $AdS_5\times S_5$ ${\cal N}=4$ super Yang-Mills duality, and the different role of the branes in the two cases is pointed out.Comment: 19 pages, Late

Alteration of dynamic quaternary structure and calcium-binding ability of β-crystallin by light

β-crystallin, one of the three main constituent proteins of the eye lens, exists as an equilibrium population of oligomeric (βH), trimeric (βL1) and dimeric (βL2) species. This equlibrium is dependent on various factors such as the protein concentration, ionic strength and pH of the medium. WE have studied the effect of ultraviolet B radiation on the aggregational patterns of β-crystallin, using size-exclusion chromatography. Irradiation of a solution of βH-crystallin at 295 nm for about 30 min causes the deaggregation of the hexameric population into dimers. Irradiation for a longer time, however, produces cross-linked high molecular weight products. Irradiation of a βL2 solution for 30 min does not perturb the elution profile, while irradiation for a longer time increases the content of βL1 (trimeric) crystallin. Irradiation also causes a decrease in the calcium-binding affinity of the β-crystallins

Current practice patterns of supraglottic airway device usage in paediatric patients amongst anaesthesiologists: A nationwide survey

Background and Aims: Supraglottic airway devices (SGADs) are increasingly being used for airway management in paediatric patients undergoing general anaesthesia. This survey was designed to assess the nationwide practice patterns of SGAD usage in paediatric patients. Methods: A questionnaire of 28 questions was circulated amongst 16,532 members of the Indian Society of Anaesthesiologists through online survey engine Google Forms® and served manually to 500 delegates attending the Asian Society of Paediatric Anaesthesiologists conference 2017. Percentage, mean and standard deviation were calculated using Microsoft Excel 2016 (Redmond, WA, USA). Results: Four hundred and five (2.3%) valid responses were obtained. The most commonly used device was i-gel© (60.74%). Three hundred and four (75.06%) respondents had access to second-generation SGADs. Second-generation devices (60.74%) were more commonly used than first-generation devices (39.26%). Anaesthesiologists utilised SGADs in various challenging scenarios such as in the difficult airway (53.33%), remote locations (55.47%), ophthalmologic (38.77%) and long-duration surgeries (17.53%). Sixty per cent respondents did not use SGADs in laparoscopic surgery. Disposable SGADs were reused by 77.28% respondents. Oropharyngeal seal and intracuff pressures were not measured by 86.91% and 56.92% respondents, respectively. Difficulty in size selection (84.19%), securing position (82.22%) and maintaining unobstructed ventilation (78.76%) were common problems encountered while using SGADs. Conclusion: Although there is a widespread use of second-generation SGADs in Indian paediatric anaesthesia, safe practices such as using capnography, measurement of oropharyngeal seal pressure, cuff pressure and appropriate disinfection are lacking