The moving boundary problem in the presence of a dipole magnetic field

An exact analytic solution is obtained for a uniformly expanding, neutral, infinitely conducting plasma sphere in an external dipole magnetic field. The electrodynamical aspects related to the radiation and transformation of energy were considered as well. The results obtained can be used in analyzing the recent experimental and simulation data.Comment: 17 pages, 1 figure, Submitted to J. Phys. A, Math. and Genera

An exact solution of the moving boundary problem for the relativistic plasma expansion in a dipole magnetic field

An exact analytic solution is obtained for a uniformly expanding, neutral, highly conducting plasma sphere in an ambient dipole magnetic field with an arbitrary orientation of the dipole moment in the space. Based on this solution the electrodynamical aspects related to the emission and transformation of energy have been considered. In order to highlight the effect of the orientation of the dipole moment in the space we compare our results obtained for parallel orientation with those for transversal orientation. The results obtained can be used to treat qualitatively experimental and simulation data, and several phenomena of astrophysical and laboratory significance.Comment: 7 pages, 2 figures. arXiv admin note: substantial text overlap with arXiv:physics/060323

Self-similar analytical model of the plasma expansion in a magnetic field

The study of hot plasma expansion in a magnetic field is of interest for many astrophysical applications. In order to observe this process in laboratory, an experiment is proposed in which an ultrashort laser pulse produces a high-temperature plasma by irradiation of a small target. In this paper an analytical model is proposed for an expanding plasma cloud in an external dipole or homogeneous magnetic field. The model is based on the self-similar solution of a similar problem which deals with sudden expansion of spherical plasma into a vacuum without ambient magnetic field. The expansion characteristics of the plasma and deceleration caused by the magnetic field are examined analytically. The results obtained can be used in treating experimental and simulation data, and many phenomena of astrophysical and laboratory significance.Comment: 10 pages, 2 figure

Renormalized cluster expansion of the microfield distribution in a strongly coupled two-component plasmas

The electric microfield distribution (MFD) at an impurity ion is studied for two-component (TCP) electron-ion plasmas using molecular dynamics simulation and theoretical models. The particles are treated within classical statistical mechanics using an electron-ion Coulomb potential regularized at distances less than the de Broglie length to take into account quantum-diffraction effects. Corrections to the potential-of-mean-force exponential (PMFEX) approximation recently proposed for MFD in a strongly coupled TCP [Phys. Rev. E 72, 036403 (2005)] are obtained and discussed. This has been done by a generalization of the standard Baranger-Mozer and renormalized cluster expansion techniques originally developed for the one-component plasmas to the TCPs. The results obtained for a neutral point are compared with those from molecular dynamics simulations. It is shown that the corrections do not help to improve the PMFEX approximation for a TCP with low ionic charge Z. But starting with Z > 5 the PMFEX model is substantially improved and the agreement with numerical simulations is excellent. We have also found that with increasing coupling the PMFEX approximation becomes invalid to predict the MFD at a neutral point while its corrected version agrees satisfactory with the simulations.Comment: 17 pages, 10 figures, submitted to Physical Review

Comparative analysis of the effect of drugs lowering intraocular pressure on a primary culture of human corneal epithelium and A549 immortalized cell line

Background. Glaucoma as one of the most common eye diseases can be a comorbid condition of an epithelial corneal defect of various etiologies. Maintaining an optimal level of ophthalmotonus includes the prescription of antiglaucoma drugs, including benzalkonium chloride-preserved drugs.The aim of the study. To compare the effect of antiglaucoma drugs, as well as benzalkonium chloride (BC), on a primary culture of human corneal epithelium and A549 immortalized cell line.Methods. The effect of brimonidine, dorzolamide and timolol (1/100, 1/50, 1/20 and 1/10 dilutions; exposure 24 hours) on a monolayer of a human corneal epithelial primary culture and A549 immortalized cell line was assessed by structural changes in cells (phase-contrast microscopy) and MTT assay data. The cytotoxic effect of BC was studied in concentrations corresponding to its content in these dilutions of the antiglaucoma drug. Using a model of a linear defect in the monolayer of a corneal epithelial primary culture and A549 immortalized cell line, the effects of brimonidine, dorzolamide and timolol (1/100 and 1/20 dilutions; exposure 48 hours) were assessed by cell migration activity.Results. Among drugs (BC-free), dorzolamide (1/50, 1/20 and 1/10 dilutions) causes minor structural changes in human corneal epithelium and A549 immortalized cell line; timolol (1/100, 1/50, 1/20 and 1/10 dilutions) causes minor structural changes in A549 immortalized cell line. Structural changes in both types of cells, a decrease in their metabolic and migration activity occur under the influence of dorzolamide, brimonidine and timolol (BC-preserved) in 1/100, 1/50, 1/20 and 1/10 dilutions. BC at the studied concentrations exhibits a similar effect.Conclusion. The cytotoxic effect of antiglaucoma drugs is caused by the presence of BC in their composition. Despite similar morphofunctional changes in cells, A549 immortalized cell line is more resistant to the effects of drugs than the human corneal epithelial primary culture. When using it as a cellular model, it is advisable to change the experimental conditions (duration of exposure and concentration of the studied drug)