29 research outputs found
Deepening the understanding of CNVs on chromosome 15q11â13 by using hiPSCs: An overview
- Author
- Publication venue
- 'Frontiers Media SA'
- Publication date
- 01/01/2023
- Field of study
The human α7 neuronal nicotinic acetylcholine receptor gene (CHRNA7) is widely expressed in the central and peripheral nervous systems. This receptor is implicated in both brain development and adult neurogenesis thanks to its ability to mediate acetylcholine stimulus (Ach). Copy number variations (CNVs) of CHRNA7 gene have been identified in humans and are genetically linked to cognitive impairments associated with multiple disorders, including schizophrenia, bipolar disorder, epilepsy, Alzheimerâs disease, and others. Currently, α7 receptor analysis has been commonly performed in animal models due to the impossibility of direct investigation of the living human brain. But the use of model systems has shown that there are very large differences between humans and mice when researchers must study the CNVs and, in particular, the CNV of chromosome 15q13.3 where the CHRNA7 gene is present. In fact, human beings present genomic alterations as well as the presence of genes of recent origin that are not present in other model systems as well as they show a very heterogeneous symptomatology that is associated with both their genetic background and the environment where they live. To date, the induced pluripotent stem cells, obtained from patients carrying CNV in CHRNA7 gene, are a good in vitro model for studying the association of the α7 receptor to human diseases. In this review, we will outline the current state of hiPSCs technology applications in neurological diseases caused by CNVs in CHRNA7 gene. Furthermore, we will discuss some weaknesses that emerge from the overall analysis of the published articles
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Azimuthal correlations of high transverse momentum jets at next-to-leading order in the parton branching method
- Author
- Publication venue
- European Physical Journal C
- Publication date
- 01/03/2022
- Field of study
AbstractThe azimuthal correlation, ÎÏ12â
Î
Ï
12
, of high transverse momentum jets in pp collisions at sâ=13
s
=
13
 TeV is studied by applying PB-TMD distributions to NLO calculations via MCatNLO together with the PB-TMD parton shower. A very good description of the cross section as a function of ÎÏ12â
Î
Ï
12
is observed. In the back-to-back region of ÎÏ12ââÏ
Î
Ï
12
â
Ï
, a very good agreement is observed with the PB-TMD Set 2 distributions while significant deviations are obtained with the PB-TMD Set 1 distributions. Set 1 uses the evolution scale while Set 2 uses transverse momentum as an argument in αsâ
α
s
, and the above observation therefore confirms the importance of an appropriate soft-gluon coupling in angular ordered parton evolution. The total uncertainties of the predictions are dominated by the scale uncertainties of the matrix element, while the uncertainties coming from the PB-TMDs and the corresponding PB-TMD shower are very small. The ÎÏ12â
Î
Ï
12
measurements are also compared with predictions using MCatNLO together Pythia8, illustrating the importance of details of the parton shower evolution.</jats:p
Azimuthal correlations of high transverse momentum jets at next-to-leading order in the parton branching method
- Author
- Publication venue
- European Physical Journal C
- Publication date
- 01/01/2021
- Field of study
AbstractThe azimuthal correlation, ÎÏ12â
Î
Ï
12
, of high transverse momentum jets in pp collisions at sâ=13
s
=
13
 TeV is studied by applying PB-TMD distributions to NLO calculations via MCatNLO together with the PB-TMD parton shower. A very good description of the cross section as a function of ÎÏ12â
Î
Ï
12
is observed. In the back-to-back region of ÎÏ12ââÏ
Î
Ï
12
â
Ï
, a very good agreement is observed with the PB-TMD Set 2 distributions while significant deviations are obtained with the PB-TMD Set 1 distributions. Set 1 uses the evolution scale while Set 2 uses transverse momentum as an argument in αsâ
α
s
, and the above observation therefore confirms the importance of an appropriate soft-gluon coupling in angular ordered parton evolution. The total uncertainties of the predictions are dominated by the scale uncertainties of the matrix element, while the uncertainties coming from the PB-TMDs and the corresponding PB-TMD shower are very small. The ÎÏ12â
Î
Ï
12
measurements are also compared with predictions using MCatNLO together Pythia8, illustrating the importance of details of the parton shower evolution.</jats:p
Recommended from our members
Measurement of energy correlators inside jets and determination of the strong coupling αS(mZ)
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
- Abbott S
- Abbrescia M
- Abdullin S
- Abreu A
- Abu Zeid S
- Acharya H
- Acharya S
- Acosta D
- Adam W
- Adamidis K
- Adamov G
- Adams MR
- Adams T
- Addesa FM
- Adloff C
- Adzic P
- Aebi D
- Afanasiev S
- Agapitos A
- Agarwal G
- Agram J-L
- Aguilar-Benitez M
- Agyel D
- Ahmad A
- Ahmad M
- Ahmed A
- AimĂš C
- Ajmal S
- Akchurin N
- Akgun B
- Akpinar A
- Al Kadhim A
- Albrecht A
- Albrecht S
- Albrow M
- Alcaraz Maestre J
- Alcerro Alcerro LF
- Aldaya Martin M
- AldĂĄ JĂșnior WL
- Aleksandrov A
- Alexander J
- Alhusseini M
- Alimena J
- Alison J
- Allmond B
- Ally D
- Almond J
- Alpana A
- Alsufyani B
- Alvarez Gonzalez B
- Alverson G
- Alves Gallo Pereira M
- Alves GA
- Aly R
- Alyari M
- Amapane N
- Ambrozas M
- Ameen MM
- Amendola C
- Amoroso S
- Amram O
- Amsler C
- An S
- An Y
- Anagnostou G
- Andrea J
- Andreev V
- Andreev Y
- Andrejkovic JW
- Andrews MB
- Androsov K
- Anguiano J
- Antchev G
- Anthony D
- Antonello M
- Apollinari G
- Apparu D
- Appelt E
- Apresyan A
- Araujo M
- Aravind A
- Arcaro D
- Arcidiacono R
- Ardino R
- Argiro S
- Arneodo M
- Aruta C
- Asawatangtrakuldee C
- Asenov P
- Asghar MI
- Asilar E
- Askew A
- Assiouras P
- Atakisi IO
- Attikis A
- Auffray E
- Aushev T
- Auzinger G
- Avati V
- Avery P
- Avila C
- Awais A
- Awan MIM
- Ayala E
- Ayala G
- Aydilek O
- Azarkin M
- Azzi P
- Azzurri P
- Baarmand MM
- Babaev A
- Babbar J
- Bacchetta N
- Bachtis M
- Backhaus M
- Baden A
- Baechler J
- Bagliesi G
- Bahinipati S
- Bainbridge R
- Bak G
- Bakas G
- Bakhshiansohi H
- Bakshi AS
- Bala A
- Baldenegro Barrera C
- Ball AH
- Bam B
- Ban Y
- Band R
- Bandyopadhyay H
- Banerjee S
- Banerjee S
- Bansal S
- Baradia S
- Barbagli G
- Barberis E
- Barbosa Trujillo DA
- Bardelli G
- Bargassa P
- Baringer P
- Barman S
- Barnes VE
- Barney D
- Barria P
- Barroso Ferreira Filho M
- Bartek R
- Bartosik N
- BartĂłk M
- Barzdukas A
- Basile C
- Basnet A
- Bastos D
- Battilana C
- Baty A
- Bauer G
- Bauerdick LAT
- Bautista I
- Baxter S
- Bayatmakou M
- Bean A
- Beauceron S
- Beaudette F
- Becerril Gonzalez H
- Bedoya CF
- Behera PK
- Behera SC
- Behnke O
- Bein S
- BeirĂŁo Da Cruz E Silva C
- Belforte S
- Bell KW
- Bellan R
- Bellato M
- Belloni A
- Bellora A
- Belvedere A
- Belyaev A
- Belyaev A
- Benaglia A
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- Bendavid J
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- Benitez JF
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- Bernardes CA
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- Besancon M
- Bestintzanos I
- Bethani A
- Bevilacqua T
- Beyrouthy T
- Bhardwaj A
- Bharthuar S
- Bhat PC
- Bhatnagar V
- Bhattacharya R
- Bhattacharya S
- Bhattacharya S
- Bhattacharya S
- Bhowmik D
- Bhowmik S
- Bhyun JH
- Bialkowska H
- Bianchini L
- Bianco M
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- Biino C
- Bilei GM
- Bilin B
- Bin Anuar AA
- Bin Norjoharuddeen N
- Bisello D
- Black K
- Blanco FernĂĄndez S
- Blancon B
- Blekman F
- Blend D
- Blinov V
- Bloch D
- Bloch P
- Bloom K
- Bluj M
- Blumenfeld B
- Boccali T
- Bocci A
- Bodek A
- Boimska B
- Boldrini G
- Boletti A
- Bollweg S
- Bols ES
- Bonacorsi D
- Bonanomi M
- Bonilla J
- Boos E
- Boran F
- Borca C
- Borgonovi L
- Bornheim A
- Borras K
- Borshch V
- Bortignon P
- Bose T
- Bossini E
- Botta C
- Botta V
- Bouchamaoui H
- Boudoul G
- Bouhali O
- Bourilkov D
- Bower S
- Boyaryntsev A
- Bozzo M
- Bragagnolo A
- Braghieri A
- Brainerd C
- Brandao Malbouisson H
- Branson JG
- Breedon R
- Brennan L
- Brew C
- Bright-Thonney S
- Brigljevic V
- Brinkerhoff A
- Brivio F
- Brochero Cifuentes JA
- Brom J-M
- Brommer S
- Brondolin E
- Brooke JJ
- Brown CE
- Brown RM
- Bruno G
- Bruschini D
- Bryant P
- Brzhechko D
- BrĂŒcken E
- Bubanja I
- Bucci R
- Buchmuller O
- Buchot Perraguin A
- Budkouski D
- Bueghly J
- Bundock A
- Bunkowski K
- Buontempo S
- Burkart M
- Burkett K
- Bury F
- Busson P
- Butalla S
- Butler JN
- Butler PH
- Butz E
- Bylsma B
- BĂ€rtschi P
- Cabrera A
- Cabrillo IJ
- Cacchio V
- Cadamuro L
- Cagnotta A
- Caillol C
- Cakir A
- Calandri A
- Calderon De La Barca Sanchez M
- Calderon A
- Cali IA
- Calligaris L
- Calzaferri S
- Camaiani B
- Caminada L
- Campagnari C
- Campana M
- Campanini R
- Campbell A
- Camporesi T
- Candelise V
- Canelli MF
- Canepa A
- Cankocak K
- Capiluppi P
- Cappati A
- Caputo C
- Caraway B
- Cardini A
- Cardwell B
- Carlin R
- Carnahan T
- Carnevali F
- Carrera Jarrin E
- Carrigan M
- Carrillo Montoya CA
- Cartiglia N
- Carvalho W
- Casarsa M
- Cassese A
- Castaldi R
- Castaneda Hernandez A
- Castells S
- Castilla-Valdez H
- Castro A
- Cavallari F
- Cavallo FR
- Cavallo N
- Cavanaugh R
- Cazzaniga C
- Ceard L
- Ceccarelli R
- Cepeda M
- Cerati GB
- Cerci S
- Cerminara G
- Cerrada M
- Cerri O
- Cetorelli F
- Chabert EC
- Chahal GS
- Chandra S
- Chang P
- Chanon N
- Chao Y
- Charlot C
- Chatagnon P
- Chatterjee RM
- Chatterjee S
- Chatterjee S
- Chatzistavrou T
- Chaudhary G
- Chauhan S
- Chawla R
- Checchia P
- Chekhovsky V
- Chen GM
- Chen HS
- Chen KF
- Chen M
- Chen PS
- Chen X
- Chen Y
- Chen YM
- Chen Z
- Chen ZG
- Chenarani S
- Cheng C
- Cheng T
- Cherepanov V
- Chernyavskaya N
- Chertok M
- Cheung HWK
- Chhetri A
- Chiarito B
- Chinellato J
- Chistov R
- Chitroda BK
- Chiusi M
- Chlebana F
- Choi J
- Choi J
- Choi M
- Choi S
- Chou JP
- Choudhary BC
- Christoforou K
- Chudasama R
- Chwalek T
- Ciangottini D
- Ciocci MA
- Cipriani M
- Citron M
- Cittolin S
- Ciulli V
- Civinini C
- Claes DR
- Clare R
- Clement E
- Clerbaux B
- Cockerill DJA
- Coelho E
- Colaleo A
- Coldham K
- Cole JE
- Colino N
- Collard C
- Colling D
- Colombina F
- Connor P
- Consuegra RodrĂguez S
- Contardo D
- Conway J
- Cooke C
- Cooper SI
- Cooperstein S
- Corcodilos L
- Cormier K
- Correia Silva G
- Cosby C
- Cossutti F
- Costa M
- Costa S
- Coubez X
- Couderc F
- Cousins R
- Covarelli R
- Cox B
- Cox PT
- Cranshaw DJ
- Creanza D
- Cremaldi LM
- Cremonesi M
- Crossman B
- Crotte Ledesma H
- CsanĂĄd M
- Csorgo T
- Cuevas J
- Cuffiani M
- Cumalat JP
- Cummings G
- Cunqueiro Mendez L
- Cussans D
- Cutts D
- Czellar S
- Da Costa EM
- Da Molin G
- Da Silveira GG
- Dabrowski A
- Dallavalle GM
- Damanakis K
- Damas F
- Damgov J
- Dancu JS
- Danilov M
- Dansana S
- Darwish MR
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- Das I
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- Daskalakis G
- Dasu S
- Datta A
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- Dauncey P
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- De Coen M
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- de TrocĂłniz JF
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- Del Re D
- Delaere C
- Delannoy AG
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- Delgado Peris A
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- Della Ricca G
- DellâOrso R
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- Dumanoglu I
- Durkin LS
- Dutta I
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- Eckerlin G
- Ecklund KM
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- Eliseev D
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- Ellis KV
- Ellithi Kamel A
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- Elmetenawee W
- Elvira VD
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- Escobar Franco R
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- Estevez Banos LI
- Etesami SM
- Eusebi R
- Evangelou I
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- Filatov O
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- Finger M
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- Fiore L
- Fiorendi S
- Fiorina D
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- Fischer Y
- Flacher H
- Flix J
- Flores Avila G
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- FlĂŒgge G
- Focardi E
- Folgueras S
- Fonseca De Souza S
- Fontana Santos Alves BA
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- Ford WT
- Forthomme L
- Foudas C
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- Frankenthal A
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- Habibullah R
- Hacisahinoglu B
- Haddad Y
- Hadjiiska R
- Hadley M
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- Heredia-De La Cruz I
- Hernandez JM
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- Herwig TC
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- Jana P
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- Jaramillo J
- Jaroslawski D
- Javaid T
- Jayananda MK
- Jayatilaka B
- Jeitler M
- Jensen F
- Jeon S
- Jeppe L
- Jessop C
- Jiang CH
- Jin W
- Jindariani S
- Jofrehei A
- Johns W
- Johnson M
- Jomhari NZ
- Jones M
- Joo C
- Josa MI
- Joshi BM
- Joshi U
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- Juodagalvis A
- Kaadze K
- Kachanov V
- Kadastik M
- Kadlecsik Ă
- Kaech B
- Kaestli HC
- Kailasapathy B
- Kalbhor P
- Kalinowski A
- Kalipoliti L
- Kallonen KTS
- Kalogeropoulos A
- Kamon T
- Kamtsikis C
- Kang DY
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- Kansal B
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- Kanuganti AR
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- Kapoor A
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- Karaman G
- Karapostoli G
- Karathanasis G
- Karchin PE
- Karjavine V
- Karmakar S
- Karneyeu A
- Karunarathna N
- Kasemann M
- Kasieczka G
- Katsoulis P
- Kaur A
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- Wilson G
- Wilson J
- Wimpenny S
- Winer BL
- Winterbottom D
- Wissing C
- Wittich P
- Wittig F
- Wolf M
- Wolf R
- Wood D
- Wright D
- Wu HY
- Wuchterl S
- Wulansatiti M
- Wulff JW
- Wulz C-E
- Wyslouch B
- WĂŒrthwein F
- Xiang Y
- Xiao J
- Xiao M
- Xie S
- Xie W
- Yagil A
- Yalvac M
- Yan F
- Yan X
- Yanes E
- Yang H
- Yang S
- Yang TJ
- Yang UK
- Yang Y
- Yang YC
- Yao Y
- Yarar H
- Yates BR
- Yazgan E
- Ye Y
- Ye Z
- Yi K
- Yi R
- Yigitbasi E
- Yockey H
- Yohay R
- Yoo HD
- Yoo J
- Yoo J
- Yoon I
- You Z
- Yu D
- Yu I
- Yu SS
- Yuan L
- Yuan S
- Yuldashev BS
- Yusuff I
- Zabi A
- Zabolotny W
- Zacharopoulou A
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zaza A
- Zecchinelli AG
- Zehetner P
- Zeinali M
- Zejdl P
- Zeuner WD
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang W
- Zhang Y
- Zhizhin I
- Zhokin A
- Zhou C
- Zhu RY
- Ziemons T
- Zilizi G
- Zimermmane Castro Santos A
- Zipper N
- Zisopoulos I
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zotz A
- Zou R
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Publication venue
- American Physical Society (APS)
- Publication date
- 14/08/2024
- Field of study
A preprint version of this article is available at arXiv:2402.13864v2 [hep-ex], https://arxiv.org/abs/2402.13864 . Comments: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables can be found at https://cms-results.web.cern.ch/cms-results/public-results/publications/SMP-22-015 (CMS Public Pages). Report number: CMS-SMP-22-015, CERN-EP-2024-010 .Energy correlators that describe energy-weighted distances between two or three particles in a hadronic jet are measured using an event sample of â = 13ââTeV proton-proton collisions collected by the CMS experiment and corresponding to an integrated luminosity of 36.3ââfb^â1. The measured distributions are consistent with the trends in the simulation that reveal two key features of the strong interaction: confinement and asymptotic freedom. By comparing the ratio of the measured three- and two-particle energy correlator distributions with theoretical calculations that resum collinear emissions at approximate next-to-next-to-leading-logarithmic accuracy matched to a next-to-leading-order calculation, the strong coupling is determined at the boson mass: âĄ() = 0.122âą9+0.0040 â0.0050, the most precise âĄ() value obtained using jet substructure observables.SCOAP3
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Search for dark matter particles in W+Wâ events with transverse momentum imbalance in proton-proton collisions at âs = 13 TeV
- Author
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- Aarup Petersen H
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- Zorbilmez C
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- Zuo X
- Zuolo D
- Zygala L
- Publication venue
- Springer Nature on behalf of SISSA
- Publication date
- 02/03/2024
- Field of study
A preprint version of the article is available at arXiv:2310.12229v2 [hep-ex], https://arxiv.org/abs/2310.12229v2 . Comments: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables can be found at https://cms-results.web.cern.ch/cms-results/public-results/publications/EXO-21-012 (CMS Public Pages).A search for dark matter particles is performed using events with a pair of W bosons and large missing transverse momentum. Candidate events are selected by requiring one or two leptons (â = electrons or muons). The analysis is based on proton-proton collision data collected at a center-of-mass energy of 13 TeV by the CMS experiment at the LHC and corresponding to an integrated luminosity of 138 fbâ1. No significant excess over the expected standard model background is observed in the âÎœqq and 2â2Îœ final states of the W+Wâ boson pair. Limits are set on dark matter production in the context of a simplified dark Higgs model, with a dark Higgs boson mass above the W+Wâ mass threshold. The dark matter phase space is probed in the mass range 100â300 GeV, extending the scope of previous searches. Current exclusion limits are improved in the range of dark Higgs masses from 160 to 250 GeV, for a dark matter mass of 200 GeV.SCOAP3
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Search for resonances in events with photon and jet final states in proton-proton collisions at sqrts = 13 TeV
- Author
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- Publication venue
- Springer Nature on behalf of SISSA
- Publication date
- 13/12/2023
- Field of study
A preprint version of the article is available at arXiv:2305.07998v2 [hep-ex], https://arxiv.org/abs/2305.07998v2 . Comments: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables can be found at https://cms-results.web.cern.ch/cms-results/public-results/publications/EXO-20-012 (CMS Public Pages). Report number: CMS-EXO-20-012, CERN-EP-2023-064.A search for resonances in events with the Îł+jet final state has been performed using proton-proton collision data collected at âs = 13 TeV by the CMS experiment at the LHC. The total data analyzed correspond to an integrated luminosity of 138 fbâ1. Models of excited quarks and quantum black holes are considered. Using a wide-jet reconstruction for the candidate jet, the Îł+jet invariant mass spectrum measured in data is examined for the presence of resonances over the standard model continuum background. The background is estimated by fitting the mass distribution with a functional form. The data exhibit no statistically significant deviations from the expected standard model background. Exclusion limits at 95% confidence level on the resonance mass and other parameters are set. Excited light-flavor quarks (excited bottom quarks) are excluded up to a mass of 6.0 (3.8) TeV. Quantum black hole production is excluded for masses up to 7.5 (5.2) TeV in the Arkani-Hamed-Dimopoulos-Dvali (Randall-Sundrum) model. These lower mass bounds are the most stringent to date among those obtained in the Îł+jet final state.SCOAP3
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Search for WâČ bosons decaying to a top and a bottom quark in leptonic final states in proton-proton collisions at sâ = 13 TeV
- Author
- Aarrestad TK
- Aarup Petersen H
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- Yusuff I
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- Zabolotny W
- Zacharopoulou A
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- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zaza A
- Zecchinelli AG
- Zehetner P
- Zeinali M
- Zejdl P
- Zeuner WD
- Zghiche A
- Zhang F
- Zhang H
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- Zhizhin I
- Zhokin A
- Zhou C
- Zhu RY
- Ziemons T
- Zilizi G
- Zimermmane Castro Santos A
- Zipper N
- Zisopoulos I
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zotz A
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- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Publication venue
- Springer Nature
- Publication date
- 05/04/2024
- Field of study
A preprint version of the article is available at arXiv:2310.19893v1 [hep-ex], https://arxiv.org/abs/2310.19893v1 . Comments: Submitted to the Journal of High Energy Physics. All figures and tables can be found at https://cms-results.web.cern.ch/cms-results/public-results/publications/B2G-20-012 (CMS Public Pages). Report number: CMS-B2G-20-012, CERN-EP-2023-213.A search for W' bosons decaying to a top and a bottom quark in final states including an electron or a muon is performed with the CMS detector at the LHC. The analyzed data correspond to an integrated luminosity of 138 fb^{-1} of proton-proton collisions at a center-of-mass energy of 13 Tev. Good agreement with the standard model expectation is observed and no evidence for the existence of the W' boson is found over the mass range examined. The largest observed deviation from the standard model expectation is found for a W' boson mass (mWâČ) hypothesis of 3.8 TeV with a relative decay width of 1%, with a local (global) significance of 2.6 (2.0) standard deviations. Upper limits on the production cross sections of W' bosons decaying to a top and a bottom quark are set. Left- and right-handed W' bosons with mWâČ below 3.9 and 4.3 TeV, respectively, are excluded at the 95% confidence level, under the assumption that the new particle has a narrow decay width. Limits are also set for relative decay widths up to 30%. These are the most stringent limits to date on this W' boson decay channel.SCOAP3
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- Yu SS
- Yuan L
- Yuan S
- Yuldashev BS
- Yusuff I
- Yzquierdo AP-C
- Zabi A
- Zabolotny W
- Zacharopoulou A
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zaza A
- Zecchinelli AG
- Zehetner P
- Zeid SA
- Zeinali M
- Zejdl P
- Zeuner WD
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
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- Zhizhin I
- Zhokin A
- Zhou C
- Zhu RY
- Ziemons T
- Zilizi G
- Zipper N
- Zisopoulos I
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zotz A
- Zou R
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Ălvarez CR
- Publication venue
- Springer Nature
- Publication date
- 04/09/2024
- Field of study
A preprint version of the article is available at: arXiv:2402.15366v2 [physics.ins-det], https://arxiv.org/abs/2402.15366 . Comments: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables can be found at https://cms-results.web.cern.ch/cms-results/public-results/publications/MLG-23-001 (CMS Public Pages). Report numbers: CMS-MLG-23-001, CERN-EP-2023-303.Data Availability: No datasets were generated or analyzed during the current study.Computing demands for large scientific experiments, such as the CMS experiment at the CERN LHC, will increase dramatically in the next decades. To complement the future performance increases of software running on central processing units (CPUs), explorations of coprocessor usage in data processing hold great potential and interest. Coprocessors are a class of computer processors that supplement CPUs, often improving the execution of certain functions due to architectural design choices. We explore the approach of Services for Optimized Network Inference on Coprocessors (SONIC) and study the deployment of this as-a-service approach in large-scale data processing. In the studies, we take a data processing workflow of the CMS experiment and run the main workflow on CPUs, while offloading several machine learning (ML) inference tasks onto either remote or local coprocessors, specifically graphics processing units (GPUs). With experiments performed at Google Cloud, the Purdue Tier-2 computing center, and combinations of the two, we demonstrate the acceleration of these ML algorithms individually on coprocessors and the corresponding throughput improvement for the entire workflow. This approach can be easily generalized to different types of coprocessors and deployed on local CPUs without decreasing the throughput performance. We emphasize that the SONIC approach enables high coprocessor usage and enables the portability to run workflows on different types of coprocessors.SCOAP3. Open access funding provided by CERN (European Organization for Nuclear Research
Recommended from our members
Search for long-lived heavy neutral leptons with lepton flavour conserving or violating decays to a jet and a charged lepton
- Author
- Aarrestad TK
- Aarup Petersen H
- Abbaneo D
- Abbiendi G
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- Yi R
- Yigitbasi E
- Yockey H
- Yohay R
- Yoo HD
- Yoo J
- Yoo J
- Yoon I
- You Z
- Yu D
- Yu I
- Yu SS
- Yuan L
- Yuan S
- Yuldashev BS
- Yusuff I
- Zabi A
- Zabolotny W
- Zacharopoulou A
- Zaleski S
- Zalewski P
- Zanetti M
- Zarubin A
- Zarucki M
- Zaza A
- Zecchinelli AG
- Zehetner P
- Zeinali M
- Zejdl P
- Zeuner WD
- Zghiche A
- Zhang F
- Zhang H
- Zhang J
- Zhang L
- Zhang W
- Zhang Y
- Zhizhin I
- Zhokin A
- Zhou C
- Zhu RY
- Ziemons T
- Zilizi G
- Zimermmane Castro Santos A
- Zipper N
- Zisopoulos I
- Zoi I
- Zolkapli Z
- Zorbakir IS
- Zorbilmez C
- Zotto P
- Zotz A
- Zou R
- Zucchetta A
- Zumerle G
- Zuo X
- Zuolo D
- Zygala L
- Publication venue
- Springer Nature on behalf of SISSA
- Publication date
- 19/03/2024
- Field of study
A preprint version of the article is available at arXiv:2312.07484v3 [hep-ex], https://arxiv.org/abs/2312.07484 . Comments: Replaced with the published version. Added the journal reference and the DOI. All the figures and tables can be found at https://cms-results.web.cern.ch/cms-results/public-results/publications/EXO-21-013 (CMS Public Pages)A search for long-lived heavy neutral leptons (HNLs) is presented, which considers the hadronic final state and coupling scenarios involving all three lepton generations in the 2-20 GeV HNL mass range for the first time. Events comprising two leptons (electrons or muons) and jets are analyzed in a data sample of proton-proton collisions, recorded with the CMS experiment at the CERN LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 138 fbâ1. A novel jet tagger, based on a deep neural network, has been developed to identify jets from an HNL decay using various features of the jet and its constituent particles. The network output can be used as a powerful discriminating tool to probe a broad range of HNL lifetimes and masses. Contributions from background processes are determined from data. No excess of events in data over the expected background is observed. Upper limits on the HNL production cross section are derived as functions of the HNL mass and the three coupling strengths VâN to each lepton generation â and presented as exclusion limits in the coupling-mass plane, as lower limits on the HNL lifetime, and on the HNL mass. In this search, the most stringent limit on the coupling strength is obtained for pure muon coupling scenarios; values of |VÎŒN|2 > 5 (4) Ă 10â7 are excluded for Dirac (Majorana) HNLs with a mass of 10 GeV at a confidence level of 95% that correspond to proper decay lengths of 17 (10) mm.SCOAP3
Tra Public e Digital History: la soluzione ibrida dei registri parrocchiali di Monterosso on line
- Publication venue
- country:ITA
- Publication date
- 01/01/2022
- Field of study
I registri parrocchiali rappresentano la prima forma nota di registro anagrafico in Europa e, come tali, vanno a costituire un patrimonio di grande importanza per lo studio delle comunitĂ di etĂ moderna e contemporanea dal punto di vista storico, demografico e genealogico. I registri, infatti, sono libri manoscritti â o misti con parte di testo a stampa â che raccolgono i dati relativi a battesimi, matrimoni e funerali officiati in una parrocchia.
I registri parrocchiali di Monterosso al Mare (La Spezia) â battesimo, matrimonio e morte â vanno dal 1580 fino agli anni â80 del XX secolo, e sono stati fotografati e trascritti da un cittadino della comunitĂ di Monterosso. Il signor Gustavo Moggia ha quindi reso disponibile un totale di circa 35.000 immagini (in cui sono comprese quelle con i singoli atti e quelle con recto e verso delle pagine dei registri) e circa 30.000 trascrizioni testuali. In questo articolo presentiamo la piattaforma web sviluppata per mettere questi dati a disposizione della comunitĂ di Monterosso e di tutti gli studiosi, e una prima loro analisi