Precisión de los estudiantes de psicología en la estimación de la asociación

Las tablas de contingencia son un recurso frecuente para presentar información estadística en prensa e Internet, así como en documentos técnicos usados en el trabajo profesional, aunque la enseñanza actual no presta mucha importancia a este tema, suponiendo que su interpretación es sencilla. En este trabajo analizamos la percepción de la asociación y estimación de su intensidad en tablas de contingencia en una muestra de 414 estudiantes de psicología de tres universidades españolas. Se observan respuesta similares en las tres universidades, alta consistencia entre percepción subjetiva de la asociación y precisión de la estimación y mejores resultados que los obtenidos en un estudio previo de Estepa (1994) con estudiantes de Bachillerato. Sin embargo, las estrategias al realizar el juicio de asociación son mayoritariamente incorrectas y sólo influyen en la precisión del juicio en el caso de independencia en los datos. Estos problemas podrían presentarse en otros estudiantes, por lo que los profesores debieran conocerlos para tenerlos en cuenta en la enseñanza

Intraperitoneal drain placement and outcomes after elective colorectal surgery: international matched, prospective, cohort study

Despite current guidelines, intraperitoneal drain placement after elective colorectal surgery remains widespread. Drains were not associated with earlier detection of intraperitoneal collections, but were associated with prolonged hospital stay and increased risk of surgical-site infections.Background Many surgeons routinely place intraperitoneal drains after elective colorectal surgery. However, enhanced recovery after surgery guidelines recommend against their routine use owing to a lack of clear clinical benefit. This study aimed to describe international variation in intraperitoneal drain placement and the safety of this practice. Methods COMPASS (COMPlicAted intra-abdominal collectionS after colorectal Surgery) was a prospective, international, cohort study which enrolled consecutive adults undergoing elective colorectal surgery (February to March 2020). The primary outcome was the rate of intraperitoneal drain placement. Secondary outcomes included: rate and time to diagnosis of postoperative intraperitoneal collections; rate of surgical site infections (SSIs); time to discharge; and 30-day major postoperative complications (Clavien-Dindo grade at least III). After propensity score matching, multivariable logistic regression and Cox proportional hazards regression were used to estimate the independent association of the secondary outcomes with drain placement. Results Overall, 1805 patients from 22 countries were included (798 women, 44.2 per cent; median age 67.0 years). The drain insertion rate was 51.9 per cent (937 patients). After matching, drains were not associated with reduced rates (odds ratio (OR) 1.33, 95 per cent c.i. 0.79 to 2.23; P = 0.287) or earlier detection (hazard ratio (HR) 0.87, 0.33 to 2.31; P = 0.780) of collections. Although not associated with worse major postoperative complications (OR 1.09, 0.68 to 1.75; P = 0.709), drains were associated with delayed hospital discharge (HR 0.58, 0.52 to 0.66; P < 0.001) and an increased risk of SSIs (OR 2.47, 1.50 to 4.05; P < 0.001). Conclusion Intraperitoneal drain placement after elective colorectal surgery is not associated with earlier detection of postoperative collections, but prolongs hospital stay and increases SSI risk

Raising the Bar: Improving Methodological Rigour in Cognitive Alcohol Research

Background and Aims: A range of experimental paradigms claim to measure the cognitive processes underpinning alcohol use, suggesting that heightened attentional bias, greater approach tendencies and reduced cue-specific inhibitory control are important drivers of consumption. This paper identifies methodological shortcomings within this broad domain of research and exemplifies them in studies focused specifically on alcohol-related attentional bias. Argument and analysis: We highlight five main methodological issues: (i) the use of inappropriately matched control stimuli; (ii) opacity of stimulus selection and validation procedures; (iii) a credence in noisy measures; (iv) a reliance on unreliable tasks; and (v) variability in design and analysis. This is evidenced through a review of alcohol-related attentional bias (64 empirical articles, 68 tasks), which reveals the following: only 53% of tasks use appropriately matched control stimuli; as few as 38% report their stimulus selection and 19% their validation procedures; less than 28% used indices capable of disambiguating attentional processes; 22% assess reliability; and under 2% of studies were pre-registered. Conclusions: Well-matched and validated experimental stimuli, the development of reliable cognitive tasks and explicit assessment of their psychometric properties, and careful consideration of behavioural indices and their analysis will improve the methodological rigour of cognitive alcohol research. Open science principles can facilitate replication and reproducibility in alcohol research

Statistical graphs and reading levels suggested in Chilean primary school textbooks

En este trabajo se analizan los tipos de gráficos estadísticos y los niveles de lectura de los mismos en dos series de libros de texto (12 textos) de Educación Primaria en Chile. En el estudio se ha seguido una metodología cualitativa, mediante el análisis de contenido. Los resultados evidencian un predominio de los gráficos de barras y pictogramas, y del nivel de lectura “leer dentro de los datos”. El trabajo de los gráficos se considera adecuado para este nivel, pues se siguen las directrices curriculares y se trabaja de forma gradual, con la necesidad de aumentar las actividades con niveles de lectura “leer más allá de los datos” y “leer detrás de los datos” en los cursos finales.In this paper we analyze the statistical graphs and the reading levels of those in two series of Primary education textbooks in Chile (12 books). We followed a qualitative method based on content analysis. Results suggest a predominance of bar graphs and pictograms and the “reading between data” level. The work with the graphics is adequate for primary education as the textbooks follows the curricular guidelines and introduces the topic gradually, with the need to increase activities with reading levels "read beyond the data" and "read behind the data" in the final courses.Proyecto EDU2013-41141-P (MEC), Grupo FQM126 (Junta de Andalucía) y Beca CONICYT PFCHA 72150306

Pollensomes as natural vehicles for pollen allergens

Olive (Olea europaea) pollen constitutes one of the most important allergen sources in the Mediterranean countries and some areas of the United States, South Africa, and Australia. Recently, we provided evidence that olive pollen releases nanovesicles of respirable size, named generically pollensomes, during in vitro germination. Olive pollensomes contain allergens, such as Ole e 1, Ole e 11, and Ole e 12, suggesting a possible role in allergy. The aim of this study was to assess the contribution of pollensomes to the allergic reaction. We show that pollensomes exhibit allergenic activity in terms of patients' IgE-binding capacity, human basophil activation, and positive skin reaction in sensitized patients. Furthermore, allergen-containing pollensomes have been isolated from three clinically relevant nonphylogenetically related species: birch (Betula verrucosa), pine (Pinus sylvestris), and ryegrass (Lolium perenne). Most interesting, pollensomes were isolated from aerobiological samples collected with an eight-stage cascade impactor collector, indicating that pollensomes secretion is a naturally occurring phenomenon. Our findings indicate that pollensomes may represent widespread vehicles for pollen allergens, with potential implications in the allergic reaction

Estimación de la asociación por estudiantes de psicología

Resumen tomado de la publicaciónLas tablas de contingencia son un instrumento necesario en el trabajo de los profesionales de psicología y, en general, en ciencias de la salud, pues la emisión de un diagnóstico requiere del juicio de asociación sobre dos variables cuyos datos se presentan en una tabla de contingencia. Se describe un estudio exploratorio de la percepción de la asociación y estimación de su intensidad en tablas de contingencia en una muestra de estudiantes de psicología (62 estudiantes de la Universidad de Granada y 62 de la Universidad de Huelva). Se comparan los resultados obtenidos entre las dos Universidades, y además se compraran con los resutados derivados de resultados un estudio previo de Estepa (1993) con estudiantes de Bachillerato.NavarraBiblioteca de Navarra; Paseo de Antonio Pérez Goyena, 3; 31008 Pamplona; +34848427788; +34948169069; [email protected]

Association Between the Seed Storage Proteins 2S Albumin and 11S Globulin and Severe Allergic Reaction After Flaxseed Intake

Background: Given the increased popularity of flaxseed in meals, several cases of allergy to these seeds have been reported. Little is known about the allergens implicated in hypersensitivity reactions to flaxseed. The present study aimed to identify the allergens involved in IgE-mediated reactions in 5 patients with a clinical history of severe systemic symptoms after flaxseed consumption. Methods: Proteins that were potential allergens with IgE-binding capacity were purified from flaxseed extract using chromatography and identified via MALDI-TOF mass spectrometry. Immunoassays were performed using the 5 allergic patients’ sera tested individually and as a pool. Results: Immunoblotting of the flaxseed extract revealed a low-molecular-mass protein (around 13 kDa) in 4 of the 5 patients, while a protein of approximately 55 kDa was detected in 2 patients. The proteins were identified by mass spectrometry as flaxseed 2S albumin, which is included in the WHO/IUIS allergen nomenclature as Lin u 1, and 11S globulin. Inhibition assays revealed in vitro IgE-mediated cross-reactivity between Lin u 1 and peanut and cashew nut proteins, while IgE-mediated recognition of 11S globulin by patients’ sera was partially inhibited by several plant-derived sources. Conclusions: Seed storage proteins from flaxseed were involved in the development of severe symptoms in the 5 patients studied and exhibited cross-reactivity with other allergenic sources. Besides the severity of flaxseed allergy in patients sensitized to 2S albumin, this is the first time that 11S globulin has been identified as a potential allergen. Taking these data into account should ensure a more accurate diagnosisAntecedentes: Dada la creciente popularidad de la linaza en las comidas, se han notificado varios casos de alergia a estas semillas. La información acerca de los alérgenos implicados en las reacciones de hipersensibilidad a estas semillas es escasa. El presente trabajo pretende identificar los alérgenos implicados en las reacciones mediadas por IgE en cinco pacientes con una historia clínica de síntomas sistémicos graves tras el consumo de linaza. Métodos: Las proteínas susceptibles de ser alérgenos con capacidad de unir IgE se purificaron a partir del extracto de linaza mediante técnicas cromatográficas. Su identificación se realizó mediante espectrometría de masas MALDI-TOF. Se realizaron inmunoensayos con los sueros de los cinco pacientes alérgicos, utilizados de forma individual o como mezclas. Resultados: Cuatro de los cinco pacientes reconocieron una proteína de baja masa molecular (alrededor de 13 kDa) en inmunoensayos con extracto de linaza, mientras que dos pacientes reconocieron una proteína de aproximadamente 55 kDa. Se identificaron por espectrometría de masas como albúmina 2S de linaza, incluida en la nomenclatura de alérgenos de la OMS/IUIS como Lin u 1, y globulina 11S, respectivamente. Los ensayos de inhibición in vitro revelaron la existencia de reactividad cruzada de la Lin u 1 con las proteínas del cacahuete y del anacardo, mientras que el reconocimiento por parte de la IgE de la globulina 11S por parte de los sueros de los pacientes fue parcialmente inhibido por varias fuentes vegetales. Conclusiones: Las proteínas de almacenamiento de las semillas de lino estaban implicadas en el desarrollo de síntomas graves en cinco individuos y mostraron una reactividad cruzada con otras fuentes alergénicas. Además de la gravedad de la alergia a la linaza en los pacientes sensibilizados a la albúmina 2S, es la primera vez que se identifica la globulina 11S como un alérgeno potencial. Consideramos que estos datos deben ser tenidos en cuenta para un diagnóstico más preciso de los pacientesMinisterio de Economia y ́CompetitividadInstituto de Salud Carlos III (ISCIII)Fondo Europeo de Desarrollo Regional – FEDER for the Thematic Networks and Co-operative Research CentresMinisterio de EducaciónDepto. de Bioquímica y Biología MolecularFac. de Ciencias QuímicasTRUEpu