Oral beclometasone dipropionate in the treatment of extensive and left-sided active ulcerative colitis: a multicentre randomised study.

AIM: To explore the efficacy and safety of the topically acting steroid beclometasone dipropionate (BDP) in an oral controlled release formulation in the treatment of extensive or left-sided ulcerative colitis. METHODS: In a multicentre, randomised, parallel-group, single-blind study, patients with active mild to moderate ulcerative colitis were randomised to a 4-week treatment with BDP 5 mg/day o.d. vs. 5-ASA 0.8 g t.d.s. The primary efficacy variable was the decrease of Disease Activity Index (DAI) (clinical symptoms and endoscopic appearance of mucosa). Safety was evaluated by monitoring adverse events, vital signs, haematochemical parameters and adrenal function

Oral beclometasone dipropionate in the treatment of active ulcerative colitis: a double-blind placebo-controlled study.

AIM: To evaluate efficacy and safety of oral beclometasone dipropionate (BDP) when added to 5-ASA in the treatment of patients with active ulcerative colitis. METHODS: In a 4-week, placebo-controlled, double-blind study, patients with extensive or left-sided mild to moderate active ulcerative colitis were randomized to receive oral 5-ASA (3.2 g/day) plus BDP (5 mg/day) or placebo. Clinical, endoscopic and histologic features, and haematochemical parameters were recorded at baseline and at the end of the study

Addome acuto

In questo testo, dopo aver formulato una definizione di addome acuto, si indica la necessità di una rapida valutazione clinica iniziale della gravità del paziente. Si descrive la modalità di raccolta dell'anamnesi e di effettuazione dell'esame obiettivo. Si indicano gli esami di laboratorio e le indagini strumentali utili per la diagnosi e il monitoraggio della malattia. Dopo averne descritte le cause, si descrivono le possibilità terapeutiche, mediche e chirurgiche, a disposizione

Thallium per rectum scintigraphy, portal pressure and portal perfusion

SCOPUS: le.jFLWNAinfo:eu-repo/semantics/publishe

Prognostic value of progressive decrease in serum cholesterol in predicting survival in Child-Pugh C viral cirrhosis.

The identification of cirrhotic patients with low life expectancy is an open clinical problem. Hypocholesterolemia is frequently found in severe chronic hepatic insufficiency because the liver is the most active site of cholesterol metabolism,but poor information is available on its precise prognostic value. We evaluated the prognostic role of hypocholesterolemia in patients with advanced liver cirrhosis. Serial serum cholesterol concentrations of 34 patients with virus-induced cirrhosis,from the first appearance of Child-Pugh class C to death,were considered. To compare survival functions,we established three base-line cholesterol cut-off points (150,125,and 100 mg/dl) and stratified patients into groups A and B,with base-line cholesterol levels lower and higher than each cut-off value,respectively

NUTRITIONAL ASPECTS AND PREVALENCE OF METABOLICSYNDROME IN PATIENTSWITH QUIESCENT ULCERATIVECOLITIS

Ulcerative Colitis (UC) is typically characterized by alternating periods of activity and remission. The symptoms related to intestinal inflammation often lead to changes in lifestyle food that may also persist during remission with the consequent risk of malnutrition. The aim of our study was to evaluate the presence of nutritional deficiencies in patients with quiescent UC and the prevalence in these patients of the metabolic syndrome (MS), a clinical entity frequently associated with an improper dietary lifestyle. Material and methods: 43 consecutive UC patients (M/F = 25/18, median age 44 years) were enrolled in the study. Patients in remission according to Ulcerative Colitis Disease Activity Index (UCDAI) were only included. The diagnosis of MS was made according to the Adult Treatment Panel III (ATP III). We assessed anthropometric and laboratory parameters. It was administered a food diary to record every single food, four days a week. The estimated daily caloric needs was carried out according to physical activity and ideal body weight. The daily intake of individual nutrients was related to levels of recommended daily intake of nutrients for the Italian population. It was used Winfood Light program for the nutritional assessment