Synthesis of Oligodeoxynucleotides Using Fully Protected Deoxynucleoside 3′-Phosphoramidite Building Blocks and Base Recognition of Oligodeoxynucleotides Incorporating

molecule

Y. V. Rami Reddy * et al. /International Journal Of Pharmacy&Technology Available Online through ISSN: 0975-766X Research Article

Received on 12-02-2011 Accepted on 24-02-201

CHARACTERIZATION OF THE PHASES OF TWO HOMOLOGOUS SERIES- II

One of the puzzles of the ordering of Liquid Crystal Phases has been the observation that a less-ordered phase, the nematic phase, can occur at both a higher and a lower temperature than a more ordered phase, the smectic A phase. Although the physical properties of the lower temperature nematic are identical to the higher temperature phase, it is called the re-entrant nematic in recognition of the fact that similar phenomena have been noted in other ordered systems of Condensed Matter Physics. In this paper, we have chosen to study two model systems based on cyano-ester isomers: (4-n-alkoxyphenyl 4'cyanobenzoate [nOPCB] where n- 6,7,8,9,10 and 12 and 4-cyanophenyl 4'-nalkoxybenzoate [CPnOB] where n = 6, 8 and 10). X-ray powder diffraction patterns were made in the solid, srnectic A and smcctic C phases of these materials in order to unde~stand the molecula

-methyl-2-oxo-4 0

R factor = 0.041; wR factor = 0.101; data-to-parameter ratio = 8.9. In the title compound, C26H22N2O3, the acenaphthen-1-one ring system is nearly planar and the pyrrolidine ring adopts a distorted envelope conformation. An intermolecular C— H O hydrogen bond stabilizes the crystal structure. Related literatur

organic compounds Acta Crystallographica Section E Structure Reports Online

R factor = 0.041; wR factor = 0.117; data-to-parameter ratio = 12.9. In he title compound, C13H16N4O3, the pyrazole ring is planar (r.m.s. deviation = 0.054 A ˚). The pyran ring is not planar; the mean plane makes a dihedral angle of 1.9 (1) with the pyrazole ring. In the crystal structure, intermolecular N— H N and N—H O interactions lead to a linear chain motif. Related literature For biological applications of pyrazole and pyranopyrazole derivatives, see: Wamhoff et al. (1993).; Velaparthi et al. (2008); Magedov et al. (2007); Rovnyak et al. (1982). For the synthesis

Absorption correction: multi-scan

disorder in main residue; R factor = 0.066; wR factor = 0.192; data-to-parameter ratio = 14.6. = 72.902 (2) = 72.690 (2

Refinement

3634 reflection

Refinement

Crystal dat

Experimental

wR(F 2) = 0.14

Refinement

disorder in main residue; R factor = 0.083; wR factor = 0.247; data-to-parameter ratio = 18.1