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The Prevalence and Correlation of Non-motor Symptoms in Adult Patients with Idiopathic Focal or Segmental Dystonia
Background: Idiopathic focal dystonia is a motor syndrome associated with dysfunction of basal ganglia circuits. Observations have suggested that many other non-motor symptoms may also be part of the clinical picture. The aim was to assess the prevalence and correlation of non-motor symptoms in patients with common idiopathic focal or segmental dystonia.
Methods: In a single-center cross-sectional case–control study, we evaluated the presence of pain, neuropsychiatric symptoms, and sleep alterations in 28 patients with blepharospasm, 28 patients with cervical dystonia, 24 patients with writer’s cramp, and 80 control subjects matched for sex, age, and schooling. We obtained clinical and demographic data, and evaluated patients using the Fahn–Marsden Dystonia Rating Scale and other specific scales for dystonia. All subjects completed the following questionnaires: Beck Depression Inventory, Beck Anxiety Inventory, Social Phobia Inventory, Apathy Scale, Epworth Sleepiness Scale, Pittsburgh Sleep Quality Index, Brief Pain Scale, and the World Health Organization Quality of Life brief scale.
Results: The patients presented more symptoms of depression, anxiety, and apathy than the control subjects. They also reported worse quality of sleep and more pain complaints. Patients with blepharospasm were the most symptomatic subgroup. The patients had worse quality of life, and the presence of pain and symptoms of apathy and depression were the main influences for these findings, but not the severity of motor symptoms.
Discussion: Patients with dystonia, especially those with blepharospasm, showed higher prevalence of symptoms of depression, anxiety, apathy, worse quality of sleep, and pain. These symptoms had a negative impact on their quality of life
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness
Definiteness across languages
Definiteness has been a central topic in theoretical semantics since its modern foundation. However, despite its significance, there has been surprisingly scarce research on its cross-linguistic expression. With the purpose of contributing to filling this gap, the present volume gathers thirteen studies exploiting insights from formal semantics and syntax, typological and language specific studies, and, crucially, semantic fieldwork and cross-linguistic semantics, in order to address the expression and interpretation of definiteness in a diverse group of languages, most of them understudied. The papers presented in this volume aim to establish a dialogue between theory and data in order to answer the following questions: What formal strategies do natural languages employ to encode definiteness? What are the possible meanings associated to this notion across languages? Are there different types of definite reference? Which other functions (besides marking definite reference) are associated with definite descriptions? Each of the papers contained in this volume addresses at least one of these questions and, in doing so, they aim to enrich our understanding of definiteness