Research on the application design of new media in modern museum interior display

This paper introduces the research results of new media application design in modern museum interior display. The purpose is to explore a feasible use of new media technology to better promote the exchange and mutual learning of human civilization museum interior display design scheme or design concept. In the study of the development history of museum display design and the realization trend of cultural value, it is determined that using new media to design narrative virtual tour can attract people who hate passive indoctrination to explore actively. In the study of museum participation in culture and modern social culture, the construction of social museum is determined. The necessity, feasibility and realization of cross-regional resource co-construction and sharing are determined in the study of the current situation of museum community interconnection

Дослідження дизайну застосування нових медіа в інтер’єрі сучасного музею

This paper introduces the research results of new media application design for indoor display in modern museums. The purpose is to explore a feasible museum interior display design scheme or design concept that utilizes new media technology to better promote human civilization exchange and mutual learning. In the study of the development history and trends in the realization of museum cultural values, it has been determined that cultural exchange and creation are very important social currencies. In the study of museum display design, it has been determined that using new media for game narrative virtual roaming design can attract people who hate passive indoctrination to actively explore. In the comparative study of museum communities, the necessity and feasibility of cross regional resource co construction and sharing were determined.Ця робота представляє результати дослідження дизайну нових медіа-додатків для внутрішньої експозиції в сучасних музеях. Мета полягає в тому, щоб вивчити можливу схему дизайну експозиції інтер’єру музею або концепцію дизайну, яка використовує нові медіа-технології для кращого сприяння обміну між людьми та взаємному навчанню. Вивчаючи історію розвитку та тенденції реалізації музейних культурних цінностей, встановлено, що культурний обмін і творчість є дуже важливими суспільними валютами. Під час дослідження дизайну експозицій музеїв було встановлено, що використання нових медіа для дизайну віртуального роумінгу оповіді гри може залучити людей, які ненавидять пасивне навчання, до активного дослідження. У порівняльному дослідженні музейних спільнот визначено необхідність і доцільність міжрегіонального ресурсного співробітництва та спільного використання

A Novel Phishing Website Detection Model Based on LightGBM and Domain Name Features

Phishing attacks have evolved in terms of sophistication and have increased in sheer number in recent years. This has led to corresponding developments in the methods used to evade the detection of phishing attacks, which pose daunting challenges to the privacy and security of the users of smart systems. This study uses LightGBM and features of the domain name to propose a machine-learning-based method to identify phishing websites and maintain the security of smart systems. Domain name features, often known as symmetry, are the property wherein multiple domain-name-generation algorithms remain constant. The proposed model of detection is first used to extract features of the domain name of the given website, including character-level features and information on the domain name. The features are filtered to improve the model’s accuracy and are subsequently used for classification. The results of experimental comparisons showed that the proposed model of detection, which integrates two types of features for training, significantly outperforms the model that uses a single type of feature. The proposed method also has a higher detection accuracy than other methods and is suitable for the real-time detection of many phishing websites

SCUBE3 Is Likely a Susceptibility Gene for Systemic Lupus Erythematosus for Chinese Populations

Background. Systemic lupus erythematosus (SLE) is a complex autoimmune disease with strong genetic disposition with more than 100 susceptibility genes identified until now. However, our knowledge on SLE genetic background is still limited. The present study was aimed at evaluating the role of single nucleotide polymorphisms (SNPs) in SCUBE3, a TGF-β signaling activator, with SLE susceptibility in Chinese populations. Methods. A total of 2801 individuals (490 cases and 493 controls from GWAS cohort and 1003 cases and 815 controls from our cohort) were enrolled, and SNPs located 10 kb up- and downstream of SCUBE3 (chr6:35182190-35218609) were included in the genetic association study. Multiple layers of bioinformatics were conducted, and the levels of SCUBE3 expression were confirmed. Results. Of the 31 SNPs in SCUBE3 tested, 24 SNPs were significantly associated with SLE at p≤0.05. The top locus was rs1888822 with p=8.74∗10−6 in the discovery cohort and was confirmed by the replication cohort with p=0.012. Additionally, the levels of SCUBE3 mRNA expression were significantly lower in patients with SLE comparing with healthy controls (p=4.28∗10−4). Further expression data from ArrayExpress showed that the expression of SCUBE3 was also lower in CD3+ T cells and B cells from patients with SLE. Conclusions. Our research revealed that variants in SCUBE3, which encode SCUBE3 as a TGF-β signaling activator, can be considered as a new genetic susceptibility factor for systemic lupus erythematosus. And the reduced mRNA expression of SCUBE3 was first reported in patients with SLE