European Cities in Globalization: A Comparative Analysis Based on the Location Strategies of Advanced Producer Services

Today there is a key question that lurks behind any consideration of Europe and its cities: is this foundation core zone of the modern world-system showing symptoms of dropping out of the contemporary core zone? It certainly appears that in the period of crises since 2008, Europe has been falling behind other major world-regions. Dubbed the “austerity region” of the world, such an interpretation sees Europe as the first part of the world-economy core to be subject to what are effectively structural adjustment programmes, largely self-imposed but still resulting in a process of peripheralization. Although uneven in impact, this is clearly a result of Europe’s states failing to adequately manage and regulate the economic activities within their territories. However it is far too soon to say whether such a monumental global economic shift is happening but we can investigate the current unevenness of economic globalization amongst European states. We compare three of these states that represent different degrees of potential peripheralization: Spain showing the stronger symptoms, Germany with least symptoms, and Britain somewhere in between. Our study is based upon an original analysis of advanced producer services that combines comparisons between countries and relations between cities

Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Background Appendicitis is the most common general surgical emergency worldwide, but its diagnosis remains challenging. The aim of this study was to determine whether existing risk prediction models can reliably identify patients presenting to hospital in the UK with acute right iliac fossa (RIF) pain who are at low risk of appendicitis. Methods A systematic search was completed to identify all existing appendicitis risk prediction models. Models were validated using UK data from an international prospective cohort study that captured consecutive patients aged 16–45 years presenting to hospital with acute RIF in March to June 2017. The main outcome was best achievable model specificity (proportion of patients who did not have appendicitis correctly classified as low risk) whilst maintaining a failure rate below 5 per cent (proportion of patients identified as low risk who actually had appendicitis). Results Some 5345 patients across 154 UK hospitals were identified, of which two‐thirds (3613 of 5345, 67·6 per cent) were women. Women were more than twice as likely to undergo surgery with removal of a histologically normal appendix (272 of 964, 28·2 per cent) than men (120 of 993, 12·1 per cent) (relative risk 2·33, 95 per cent c.i. 1·92 to 2·84; P < 0·001). Of 15 validated risk prediction models, the Adult Appendicitis Score performed best (cut‐off score 8 or less, specificity 63·1 per cent, failure rate 3·7 per cent). The Appendicitis Inflammatory Response Score performed best for men (cut‐off score 2 or less, specificity 24·7 per cent, failure rate 2·4 per cent). Conclusion Women in the UK had a disproportionate risk of admission without surgical intervention and had high rates of normal appendicectomy. Risk prediction models to support shared decision‐making by identifying adults in the UK at low risk of appendicitis were identified

Coefficient stability and structural change in the Spanish economy

Input–output, Supply-side input output model, Demand-side input output model, Allocation coefficients, Technical coefficients, RAS, Controllability, observability, and system structure, 93B15 realizations from input output data,

The spatial hierarchy of technological change and economic development in Europe

O33, R3,

Why some regions will decline: A Canadian case study with thoughts on local development strategies-super-

The authors present the case of five Canadian peripheral regions, which they argue are destined to decline. The explanation of the reasons why future decline (in absolute population and employment numbers) is inevitable constitutes the article's central focus. The authors suggest that regional decline will become an increasingly common occurrence in nations at the end of the demographic transition whose economic geographies display centre-periphery relationships. Such broad structural trends cannot be easily altered by public policy. The authors reflect on the implications of regional decline for the formulation of local economic development strategies. Local economic development strategies should not, they argue, be advanced as a means of arresting population and employment decline. To suggest that the regions studied in this article will decline because of a lack of social capital or insufficient number of local entrepreneurs, is not only misleading but may also be counterproductive. Copyright (c) 2006 the author(s). Journal compilation (c) 2006 RSAI.

Gibrat’s law and the learning process

L11, L80, L26, Firm growth, Gibrat’s law, Service industries,