Epigrass: a tool to study disease spread in complex networks.

The construction of complex statial simulation models such as those used in network epidemiology, is a daunting task due to the large amount of data involved in their parameterization. Such data, which frequently resides on large geo-referenced databases, has to be processed and assigned to the various components of the model. All this just to construct the model, then it still has to be simulated and analyzed under different epidemiological scenarios. This workflow can only be achieved efficiently by computational tools that can automate most if not all these time-consuming tasks. In this paper, we present a simulation software, Epigrass, aimed to help designing and simulating network-epidemic models with any kind of node behavior.
 
A Network epidemiological model representing the spread of a directly transmitted disease through a bus-transportation network connecting mid-size cities in Brazil. Results show that the topological context of the starting point of the epidemic is of great importance from both control and preventive perspectives.

Epigrass is shown to facilitate greatly the construction, simulation and analysis of complex network models. The output of model results in standard GIS file formats facilitate the post-processing and analysis of results by means of sophisticated GIS software

DIFFERENTIATION OF EQUINE MESENCHYMAL STROMAL CELLS INTO CELLS OF NEURAL LINEAGE AND THEIR APPLICATION INTO A NOVEL MODEL FOR ACUTE PERIPHERAL NERVE INJURY IN THE HORSE

Studies have shown that mesenchymal stromal cells (MSCs) are able to differentiate into extra-mesodermal lineages, including neurons. Positive outcomes were obtained after transplantation of neurally-induced MSCs in rats, rabbits and guinea pigs after nerve injury, but the effect of these cells is unknown in horses. Our objective was to test the ability of equine mesenchymal stromal cells to differentiate into cells of neuronal lineage, and to assess differences, if any, in morphology and protein expression. Additionally, we wanted to investigate if horse age and cell passage number contributed to the ability to achieve neural differentiation. The first part of this research focuses on assessing the potential of equine bone marrow-derived mesenchymal stromal cells to undergo differentiation into cells of neural lineage cells after prior demonstration of their stemness. It describes the optimization of in vitro conditions to induce neural differentiation of equine MSCs and the use of neural markers in equine MSCs, which has not been previously reported. Subsequent research focuses on further commitment of these neural cells into Schwann-like cells for possible transplantation into an acute peripheral nerve injury model in horses. After optimizing the laboratory conditions to induce Schwann cell differentiation of equine MSCs, their detachment from the tissue culture flasks resulted in poor viability. Therefore, undifferentiated MSCs were transplanted in the surrounding fascia after transecting the central portion of the anastomotic branch (ramus communicans) of the lateral and medial palmar nerves of the fore limbs in healthy horses. Approximately 45 days after the lesion was created, the whole nerve was removed for histological analyses

LA INTERVENCION SOCIOEDUCATIVA, UNA MODALIDAD DE EDUCACION AMBIENTAL CASO: ANALISIS DE LA REVISTA IMPULSO AMBIENTAL Y MATERIALES DIDACTICOS DE LA SEMARNAT

La comunicación en todas sus facetas y formas de expresión implica necesariamente el intercambio de información a través de códigos previamente establecidos. Por medio de la comunicación se transmiten mensajes que buscan influir en el cambio de actitudes de los participantes en ésta. También es susceptible de análisis a partir de las modificaciones y agregados que va teniendo como parte del desarrollo de la disciplina. La comunicación a partir de los elementos teóricos y metodológicos que posee, permite analizar el mundo y explicarlo de mejor forma. Un caso concreto es la comunicación ambiental, la tesis muestra como la comunicación ambiental se integra a intervenciones socioeducativas. Y como a partir de las estrategias de la intervención se comprende la comunicación ambiental que genera cambios de actitud en la relación ser humano-naturaleza. En esta investigación se retoma la experiencia obtenida en el desempeño profesional en la Secretaría de Medio Ambiente y Recursos Naturales (SEMARNAT) dependiente del Gobierno Federal, una de cuyas funciones es la capacitación y divulgación del conocimiento ecológico y educación ambiental. Divulgación que se realiza en principio con el material didáctico y contenidos de la revista Impulso Ambiental, realizados por el Centro de Educación y Capacitación para el Desarrollo sustentable (CECADESU)

Diseño Integral del espacio público para la Asociación de viviendas “ Castilla la Mancha”

El proyecto Diseño Integral del espacio público para la Asociación de viviendas “ Castilla la Mancha” se concibe como una iniciativa de apoyo a la comunidad, para dotar de espacios públicos de calidad, confiándoles funciones y usos, posibilitando la localización de actividades, otorgándoles cualidades paisajísticas y ambientales, a la vez de promover la apropiación y participación de la comunidad de estos espacios como lugares propicios para la convivencia, la inclusión social y que contribuyan a la construcción de su identidad. La metodología del proyecto constituye, principalmente, la incorporación de la comunidad en el diseño y en la intervención del espacio, a diferencia del mejoramiento unilateral

Teaching quadrilaterals in Basic Secondary

La investigación buscó ofrecer desde Básica Secundaria un conocimiento geométrico básico desde los informantes clave para conformar principios para la enseñanza de los cuadriláteros y su relación con el entorno real de estudiantes de sexto grado que le permita desenvolverse en la vida cotidiana para orientarse en la resolución de problemas que incluye conocimientos respecto a los cuadriláteros. La metodología empleada fue cualitativa, basada en el método fenomenológico hermenéutico. Los informantes claves fueron cinco (5) profesores de matemática que laboran en la Institución Educativa “Francisco José Caldas”, en Colombia. Como técnicas e instrumentos de recolección de información se emplearon los diálogos. Se reflejan algunos principios didácticos para la enseñanza de los cuadriláteros extraídos de la información dada por los informantes. Palabras clave: Enseñanza de cuadriláteros; Conocimiento geométrico; Vida cotidiana; Resolución de Problemas; Entorno realThe research sought to offer from Basic Secondary School, a basic geometric knowledge from the key informants to conform principles for the teaching of quadrilaterals and their relationship with the real environment of sixth-grade students that allows them to develop in daily life to orient themselves in the resolution of problems that include knowledge regarding quadrilaterals. The methodology used was qualitative, based on the hermeneutic phenomenological method. The key informants were five (5) mathematics teachers working at the "Francisco José Caldas" Educational Institution in Colombia. Dialogues were used as data collection techniques and instruments. Some didactic principles for the teaching of quadrilaterals extracted from the information given by the informants are reflected. Keywords: Teaching quadrilaterals, Geometric knowledge, Everyday life, Problem-solving, Real environment

Nuevo hormigón: Hormigón autocompactable de resistencia media en colombia- patente de invención (marzo 2019)

In civil construction, the need to seek greater durability in structures with a denser and more compact material, resistant to the attack of the environment and that demands a lower cost of maintenance and protection has promoted the development of Self Compacting Concrete (SCC) in the world. The results obtained with the use of SCC have been convincing for its use ratifying them as a new alternative that generates security, efficiency, speed, with ostensible improvements in the work environment and providing a significant economy in different ways, in the construction process. Hence the civil construction in Colombia requires the implementation of new efficient and sustainable technologies being the Medium-Low Resistance SCCs (SCC-MR) strength between 30 MPa-45 MPa) the first tool that guarantees a fluid concrete no problems of segregation or exudation in fresh condition. These properties are determined in the laboratory and in situ. This material in Colombia, has been developed in the Laboratory of Structures of the Faculty of Mines of the National University of Colombia- Medellin following the methodology proposed for HAC-RMs, with excellent results, as presented in this Article,  for the firm ACCIONA of Spain, Expo-Camacol in Colombia, among others and whose conclusions allowed to patent for the Superintendence of Industry and Commerce, a new alternative of concrete in the world.En la construcción civil, la necesidad de buscar mayor durabilidad en las estructuras, con un material más denso y compacto, resistente al ataque del medio ambiente y que demande un menor costo de mantenimiento y protección; ha promovido el desarrollo del Hormigón Autocompactable (HAC) en el mundo. Los resultados obtenidos con el uso del HAC, han sido convincentes para el empleo del mismo; ratificándolos como una nueva alternativa que genera seguridad, eficiencia, rapidez, con mejoras ostensibles en el ambiente de trabajo y proporcionando una economía significativa de diferentes formas, en el proceso constructivo. De ahí que, en Colombia, la construcción civil exija la implementación de nuevas tecnologías eficientes y sostenibles; siendo los HACs de Resistencia Media-Baja (HAC-RM, entre 30 MPa- 45 MPa), la primera herramienta que garantiza un hormigón fluido (H.F); sin problemas de separación (segregación) o exudación en estado fresco. Dichas propiedades son determinadas en el laboratorio y en obra. Este material en Colombia, se ha desarrollado en el Laboratorio de Estructuras (LABEST) de la Facultad de Minas de la Universidad Nacional de Colombia- Sede Medellín, siguiendo la metodología propuesta para los HAC-RMs, con excelentes resultados, como se presentan en este artículo, para la firma ACCIONA de España, Expo-Camacol en Colombia, entre otros y cuyas conclusiones permitieron patentar por la Superintendencia de Industria y Comercio, una nueva alternativa de hormigón en el mundo

Magnetic mineralogy of Variscan granites from northern Portugal : an approach to their petrogenesis and metallogenic potential

Northern Portugal is characterized by the occurrence of numerous W hydrothermal deposits spatially associated with granites. The primary goal of this work is to establish a relationship between the magnetic behavior of the granites and the redox conditions during magma genesis, as this can influence the occurrence of mineralizations, namely of W (Mo). To this end, the magnetic mineralogy of the granites of the Lamas de Olo Pluton, a posttectonic pluton in northern Portugal, with associated W (Mo) occurrences was characterized and compared with the magnetic mineralogy of other post-tectonic Variscan plutons. This pluton is composed of different biotite granites: Lamas de Olo, Alto dos Cabeços and Barragem. To better characterize its magnetic behavior, different analytical techniques that complement previous magnetic susceptibility studies were performed. The magnetic mineralogy of Lamas de Olo Pluton was then compared with other post-tectonic Variscan plutons such as the Vila Pouca de Aguiar, Peneda-Gerês and Lavadores-Madalena plutons. The presence of magnetite in some of these granites is important because it points to melt-oxidized conditions not commonly found in Iberian Variscan granites. Our study shows that granite areas where magnetite and/or magnetite/ilmenite coexist are important targets for W (Mo) mineralizations. The results indicate that a few plutons have granites with a complex redox history which leads to the formation of magnetite and ilmenite