Paris sous Louis XV.

OPLADEN-RUG0

Leucoencephalite aigue hemorragique de Hurst. Presentation clinico-electroencephalographico-antomique d'um cas de la litterature et revue [Acute hemorrhagic encephalitis of Hurst. Clinical, electroencephalographic and anatomic presentation of a case from the literature and revue]

Clinical and electroencephalographic evolution, as well as the neuropathology, are described in a 25 year old man with a Hurst's acute haemorrhagic leucoencephalitis. Lesions, unusually symmetrical, coexists with those, without vascular necrosis nor haemorrhages, of the perivenous encephalomyelitis. The aspecific onset, course and results of complementary investigations appear on reviewing 44 clinical observations in the literature. Histologic examination of affected white matter is the only was to assess the diagnosis. Two features that may have been previously neglected are outlined: the predilection for 20 to 40 years old males, while the adolescent male, the most susceptible to perivenous encephalomyelitis after specific fevers, is not affected by Hurst's disease. Multiple sclerosis or a prodromal meningo-encephalitis, clinically undetected, could be not rare. Therapeutic results of surgical decompression, hyperosmolar substances and massive doses of corticosteroids (3 survivals out of 10 cases diagnosed on biopsy) cannto be evaluated at the present time. By analogy with the simple and the hyperacute forms of EAE, the myelinotoxicity may result from sensitized lymphocytes alone in the perivenous encephalomyelitis, from an association of circulating antibodies and lymphocytes in Hurst's disease. Whether the immunoglobulins enchance the cellular myelinotoxicity or induce an immune complex disease upon a perivenous encephalomyelitis is still to be determined

Skepticism and Clandestine Literature: Doutes des Pyrrhoniens

The latest studies on clandestine philosophical literature reveal the importance of this corpus to understand how skeptical tropes and lexicon were modified during the Modern Age. We will try to show it by means of an anonymous text written surely after 1711 and entitled Doutes des pyrrhoniens. First, we will present the manuscript in its most important arguments; second, we will concentrate in the eighth chapter and specially in the relationship between religion and politics; finally, we will take into account a differentiation that the author establishes between "moderate pyrrhonism" and "furious pyrrhonism" to consider its importance. Our main argument will be that the difference between these two forms of pyrrhonism is political, not epistemological. Indeed, both forms coincide in that religion is a fact of power that has nothing to do with an alleged divine revelation. The question is no longer about the truth of religion, but about whether or not it is convenient to abandon it as a regulatory component of society.Fil: Bahr, Fernando Anibal. Centro de Investigaciones Filosoficas. Instituto de Filosofia "ezequiel de Olaso". - Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Ciudad Universitaria. Instituto de Filosofia "ezequiel de Olaso".; Argentin