Alien Registration- Cronkite, Alfred D. (Blaine, Aroostook County)

https://digitalmaine.com/alien_docs/27366/thumbnail.jp

Culture of normal human blood cells in a diffusion chamber system II. Lymphocyte and plasma cell kinetics

Normal human blood leukocytes were cultured in Millipore diffusion chambers implanted into the peritoneal cavities of irradiated mice. The evaluation of survival and proliferation kinetics of cells in lymphyocytic series suggested that the lymphoid cells are formed from transition of small and/or large lymphocytes, and the lymphoblasts from the lymphoid cells. There was also evidence indicating that some of the cells in these two compartments are formed by proliferation. The evaluation of plasmacytic series suggested that the plasma cells are formed from plasmacytoid-lymphocytes by transition, and the latter from the transition of lymphocytes. In addition, relatively a small fraction of cells in these two compartments are formed by proliferation. mature plasma cells do not and immature plasma cells do proliferate. Estimation of magnitude of plasma cells formed in the cultures at day 18 indicated that at least one plasma cell is formed for every 6 normal human blood lymphocytes introduced into the culture

THE STUDY OF MENSTRUAL AND OTHER BLOOD LOSS, AND CONSEQUENT IRON DEFICIENCY BY Fesup59sup 59 WHOLE BODY COUNTING

An established method for determining radioiron absorption by whole body counting was used to study six parous women with hypochromic anemia and menorrhagia, and a seventh nulliparous woman with normal blood values and normal menses. In addition to demonstrating iron deficiency by increased radioiron absorption, the method was found useful in estimating the quantity of blood lost with each menstrual period. As much as 550 ml of menstrual loss was noted in two of the patients studied. Estimates in the patient with normal menses were 59 and 33 ml. Two additional patients demonstrated patierns of blood loss found in continuous gastrointestinal hemorrhage due to hereditary hemorrhagic telangiectasia, and in severe epistaxis, as further applications of the technique. Where available, the method is to be recommended for routine investigation of hypochromic anemia when episodic or continuous blood loss such as that of menorrhagia is suspected. (auth

ORGAN AND TISSUE RADIOACTIVITY FOLLOWING PARENTERAL ADMINISTRATION OF Cosup60sup 60 VITAMIN Bsub1sub 1sub2sub 2

Vitamin B/sub 12/, labeled with Co/sup 60/ having a specific activity of 1.0 mu C/ mu g, was administered to 18 patients in the late stages of malignandt diseases. Death occurred 11 hr to 695 days after Co -- B/sub 12/ administration. Data are presented on the distribution of Co -- B/sub 12/ in tissues andd organds obtained at post-mortem examination. From 16.8 to 108% was in the liver, with lesser amounts in the othef organds and tissues. Variations resulted from the route of administration, disesse state, and interval between administration and death. (C.H.

Alien Registration- Cronkite, Alfred D. (Blaine, Aroostook County)

https://digitalmaine.com/alien_docs/27366/thumbnail.jp