11 research outputs found

    1st Conference of African Animal Health Information Workers, 3-5 July 1995, Onderstepoort, South Africa

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    Article was scanned with HP Scanjet 5590, 24-bit true colour, 300 dpi, saved in TIFF-format. Adobe Acrobat v.9 was used for the merging and conversion to the final presentation PDF-format

    1st Conference of African Animal Health Information Workers, 3-5 July 1995, Onderstepoort, South Africa

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    World-Wide-Web (WWW) browsers, such as Netscape, Mosaic, and Lynx, have made exploring the Internet easy even for novices. A brief introduction to the terminology and a description of basic commands will be followed by a demonstration using WWW sites of interest to animal health information workers.Article was scanned with HP Scanjet 5590, 24-bit true colour, 300 dpi, saved in TIFF-format. Adobe Acrobat v.9 was used for the merging and conversion to the final presentation PDF-format

    Running wild, running free : capturing, harnessing and disseminating knowledge flows in support of animal health

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    The Washington State University Health Sciences Library (HSL) is a specialized academic library at a land-grant public university located in Pullman, WA, USA. This discussion focuses on instruction to students in the WSU College of Veterinary Medicine (CVM) during their participation in a case-based learning activity known as Diagnostic Challenges (DCs). DCs take place twice during the veterinary students' second professional year and are an intensive departure from the typical course schedule. The purposes of the DCs are to decrease discipline-based compartmentalization of the curriculum, increase the opportunities for active learning, develop students' interpersonal and communication skills, and promote independent learning skills. A literature search is a required part of these assignments. At the end of the week, the teams present synopses of their cases and the clinical reasoning they went through to design treatment regimens. Over the years a variety of strategies have been employed to help students understand both why a literature search is important as well as how to complete one. This summary provides examples of what worked, what did not, and the effects of library involvement in the program on the students' successful completion of the exercise.Poster presented at the 5th International Conference of Animal Health Information Specialists, 4-7 July 2005, Onderstepoort, South AfricaSarah K. McCord and Vicki F. Crofthttp://www.library.up.ac.za/vet/icahi

    A History of the International Conference of Animal Health Information Specialists (ICAHIS) and its Partnership in One Health

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    This article chronicles the International Conference of Animal Health Information Specialists' (ICAHIS) beginning in 1992 to the present and describes other groups and conferences formed from the international animal health information conference idea. Throughout its history, ICAHIS has been a forum for colleagues worldwide to discuss, share, and promote animal health information access. This article is a brief history of ICAHIS's origins and the movement it fostered. The 7th ICAHIS, the first in the United States, will occur in Boston, May 3-8, 2013. Previous conferences were held on three continents: Europe, Africa, and Australia

    Fostering International Communications: the Development of the Web-based International Directory of Veterinary Medical and Related Libraries

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    Contributing institutions: Washington State University; Oregon State University; University of Missouri; Cornell Universit

    Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway

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    The epidermis comprises multiple layers of specialized epithelial cells called keratinocytes. As cells are lost from the outermost epidermal layers, they are replaced through terminal differentiation, in which keratinocytes of the basal layer cease proliferating, migrate upwards, and eventually reach the outermost cornified layers. Normal homeostasis of the epidermis requires that the balance between proliferation and differentiation be tightly regulated. The GTP binding protein RhoA plays a fundamental role in the regulation of the actin cytoskeleton and in the adhesion events that are critically important to normal tissue homeostasis. Two central mediators of the signals from RhoA are the ROCK serine/threonine kinases ROCK-I and ROCK-II. We have analyzed ROCK's role in the regulation of epidermal keratinocyte function by using a pharmacological inhibitor and expressing conditionally active or inactive forms of ROCK-II in primary human keratinocytes. We report that blocking ROCK function results in inhibition of keratinocyte terminal differentiation and an increase in cell proliferation. In contrast, activation of ROCK-II in keratinocytes results in cell cycle arrest and an increase in the expression of a number of genes associated with terminal differentiation. Thus, these results indicate that ROCK plays a critical role in regulating the balance between proliferation and differentiation in human keratinocytes
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