27 research outputs found
Critical illness-induced dysglycaemia : diabetes and beyond
Type 2 diabetes has reached epidemic proportions in
many parts of the world. The disease is projected to
continue to increase and double within the foreseeable
future. Dysglycaemia develops in the form of
hyperglycaemia, hypoglycaemia and marked glucose
variability in critically ill adults whether they are known
to have premorbid diabetes or not. Patients with such
glucose dysregulation have increased morbidity and
mortality. Whether this is secondary to cause and eff ect
from dysglycaemia or is just related to critical illness
remains under intense investigation. Identifi cation of
intensive care unit (ICU) patients with unrecognised
diabetes remains a challenge. Further, there are few
data regarding the development of type 2 diabetes
in survivors after hospital discharge. This commentary
introduces the concept of critical illness-induced
dysglycaemia as an umbrella term that includes the
spectrum of abnormal glucose homeostasis in the
ICU. We outline the need for further studies in the
area of glucose regulation and for follow-up of the
natural history of abnormal glucose control during ICU
admission and beyond
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