1,690 research outputs found

    Why does the Engel method work? Food demand, economies of size and household survey methods

    Get PDF
    Estimates of household size economies are needed for the analysis of poverty and inequality. This paper shows that Engel estimates of size economies are large when household expenditures are obtained by respondent recall but small when expenditures are obtained by daily recording in diaries. Expenditure estimates from recall surveys appear to have measurement errors correlated with household size. As well as demonstrating the fragility of Engel estimates of size economies, these results help resolve a puzzle raised by Deaton and Paxson (1998) about differences between rich and poor countries in the effect of household size on food demand

    The Treatment of Activated PI3Kδ Syndrome

    Get PDF
    Activated phosphoinositide 3-kinase δ syndrome (APDS), also known as PASLI disease (p110d-activating mutation causing senescent T cells, lymphadenopathy, and immunodeficiency) are combined immunodeficiencies resulting from gain-of-function mutations in the genes (PIK3CD and PIK3R1) encoding the subunits of phosphoinositide 3-kinase δ (PI3Kδ) and were first described in 2013. These mutations result in the hyperactivation of the PI3K/AKT/mTOR/S6K signally pathways. In this mini-review we have detailed the current treatment options for APDS. These treatments including conventional immunodeficiency therapies such as immunoglobulin replacement, antibiotic prophylaxis, and hematopoietic stem cell transplant. We also discuss the more targeted therapies of mTOR inhibition with sirolimus and selective PI3Kδ inhibitors

    Gluino Contribution to the 3-loop QCD beta function in the Minimal Supersymmetric Standard Model

    Full text link
    We deduce the gluino contribution to the three-loop QCD \beta function within the minimal supersymmetric Standard Model (MSSM) from its standard QCD expression. The result is a first step in the computation of the full MSSM three-loop \beta function. In addition, in the case of a light gluino it provides the strong three-loop SUSY correction to the extrapolation of the strong coupling constant from the low energy regime to the Z region and up to the squark threshold.Comment: 11 pages, RevTex, 4 Postscript figur

    Measuring organisational readiness for patient engagement (MORE) : an international online Delphi consensus study

    Get PDF
    Date of Acceptance: 28/01/2015. © 2015 Oostendorp et al.; licensee BioMed Central. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise statedWidespread implementation of patient engagement by organisations and clinical teams is not a reality yet. The aim of this study is to develop a measure of organisational readiness for patient engagement designed to monitor and facilitate a healthcare organisation’s willingness and ability to effectively implement patient engagement in healthcarePeer reviewedFinal Published versio

    Stray-light restoration of full-disk CaII K solar observations: a case study

    Full text link
    AIMS: We investigate whether restoration techniques, such as those developed for application to current observations, can be used to remove stray-light degradation effects on archive CaII K full-disk observations. We analyze to what extent these techniques can recover homogeneous time series of data. METHODS:We develop a restoration algorithm based on a method presented by Walton & Preminger (1999). We apply this algorithm to data for both present-day and archive CaII K full-disk observations, which were acquired using the PSPT mounted at the Rome Observatory, or obtained by digitization of Mt Wilson photographic-archive spectroheliograms. RESULTS:We show that the restoring algorithm improves both spatial resolution and photometric contrast of the analyzed solar observations. We find that the improvement in spatial resolution is similar for analyzed recent and archive data. On the other hand, the improvement of photometric contrast is quite poor for the archive data, with respect to the one obtained for the present-day images. We show that the quality of restored archive data depends on the photographic calibration applied to the original observations. In particular, photometry can be recovered with a restoring algorithm if the photographic-calibration preserves the intensity information stored in the original data, principally outside the solar-disk observations.Comment: 10 pages; 9 figure

    Who wants to be involved in health care decisions? Comparing preferences for individual and collective involvement in England and Sweden

    Get PDF
    Background: Patient and public involvement (PPI) is framed as positive for individuals, the health system, public health, as well as for communities and society as a whole. We investigated whether preferences for PPI differed between two countries with Beveridge type health systems-Sweden and England. We measured willingness to be involved in individual treatment decisions and in decisions about the organization and provision of local health and social care services. Methods: This was a comparative cross-sectional study of the general population's preferences. Together, the two samples included 3125 respondents; 1625 in England and 1500 in Sweden. Country differences were analysed in a multinomial regression model controlling for gender, age and educational attainment. Results: Overall, 68% of respondents wanted a passive patient role and 44% wanted to be involved in local decisions about organization and provision of services. In comparison with in Sweden, they were in England less likely to want a health professional such as a GP or consultant to make decisions about their treatment and also more likely to want to make their own decisions. They were also less likely to want to be involved in local service development decisions. An increased likelihood of wanting to be involved in organizational decision-making was associated with individuals wanting to make their own treatment decisions. Women were less likely to want health professionals to make decisions and more likely to want to be involved in organizational decisions. Conclusions: An effective health system that ensures public health must integrate an effective approach to PPI both in individual treatment decisions and shaping local health and social care priorities. To be effective, involvement activities must take in to account the variation in the desire for involvement and the implications that this has for equity. More work is needed to understand the relationship between the desire to be involved and actually being involved, but both appear related to judgements of the impact of involvement on health care decisions
    • …
    corecore