86 research outputs found
Stripe phases in the two-dimensional Falicov-Kimball model
The observation of charge stripe order in the doped nickelate and cuprate
materials has motivated much theoretical effort to understand the underlying
mechanism of the stripe phase. Numerical studies of the Hubbard model show two
possibilities: (i) stripe order arises from a tendency toward phase separation
and its competition with the long-range Coulomb interaction or (ii) stripe
order inherently arises as a compromise between itinerancy and magnetic
interactions. Here we determine the restricted phase diagrams of the
two-dimensional Falicov-Kimball model and see that it displays rich behavior
illustrating both possibilities in different regions of the phase diagram.Comment: (5 pages, 3 figures
Limits on Phase Separation for Two-Dimensional Strongly Correlated Electrons
From calculations of the high temperature series for the free energy of the
two-dimensional t-J model we construct series for ratios of the free energy per
hole. The ratios can be extrapolated very accurately to low temperatures and
used to investigate phase separation. Our results confirm that phase separation
occurs only for J/t greater than 1.2. Also, the phase transition into the phase
separated state has Tc of approximately 0.25J for large J/t.Comment: 4 pages, 6 figure
Phase Separation Based on U(1) Slave-boson Functional Integral Approach to the t-J Model
We investigate the phase diagram of phase separation for the hole-doped two
dimensional system of antiferromagnetically correlated electrons based on the
U(1) slave-boson functional integral approach to the t-J model. We show that
the phase separation occurs for all values of J/t, that is, whether or with J, the Heisenberg coupling constant and t, the hopping
strength. This is consistent with other numerical studies of hole-doped two
dimensional antiferromagnets. The phase separation in the physically
interesting J region, is examined by introducing
hole-hole (holon-holon) repulsive interaction. We find from this study that
with high repulsive interaction between holes the phase separation boundary
tends to remain robust in this low region, while in the high J region, J/t
> 0.4, the phase separation boundary tends to disappear.Comment: 4 pages, 2 figures, submitted to Phys. Rev.
Estimation of the hydraulic parameters of unsaturated samples by electrical resistivity tomography
In situ and laboratory experiments have shown that electrical resistivity tomography (ERT) is an effective tool to image transient phenomena in soils. However, its application in quantifying soil hydraulic parameters has been limited. In this study, experiments of water inflow in unsaturated soil samples were conducted in an oedometer equipped to perform three-dimensional electrical measurements. Reconstructions of the electrical conductivity at different times confirmed the usefulness of ERT for monitoring the evolution of water content. The tomographic reconstructions were subsequently used in conjunction with a finite-element simulation to infer the water retention curve and the unsaturated hydraulic conductivity. The parameters estimated with ERT agree satisfactorily with those determined using established techniques, hence the proposed approach shows good potential for relatively fast characterisations. Similar experiments could be carried out on site to study the hydraulic behaviour of the entire soil deposi
Screening, Coulomb pseudopotential, and superconductivity in alkali-doped Fullerenes
We study the static screening in a Hubbard-like model using quantum Monte
Carlo. We find that the random phase approximation is surprisingly accurate
almost up to the Mott transition. We argue that in alkali-doped Fullerenes the
Coulomb pseudopotential is not very much reduced by retardation
effects. Therefore efficient screening is important in reducing
sufficiently to allow for an electron-phonon driven superconductivity. In this
way the Fullerides differ from the conventional picture, where retardation
effects play a major role in reducing the electron-electron repulsion.Comment: 4 pages RevTeX with 2 eps figures, additional material available at
http://www.mpi-stuttgart.mpg.de/docs/ANDERSEN/fullerene
Phase separation in the 2D Hubbard model: a fixed-node quantum Monte Carlo study
Fixed-node Green's function Monte Carlo calculations have been performed for
very large 16x6 2D Hubbard lattices, large interaction strengths U=10,20, and
40, and many (15-20) densities between empty and half filling. The nodes were
fixed by a simple Slater-Gutzwiller trial wavefunction. For each value of U we
obtained a sequence of ground-state energies which is consistent with the
possibility of a phase separation close to half-filling, with a hole density in
the hole-rich phase which is a decreasing function of U. The energies suffer,
however, from a fixed-node bias: more accurate nodes are needed to confirm this
picture. Our extensive numerical results and their test against size, shell,
shape and boundary condition effects also suggest that phase separation is
quite a delicate issue, on which simulations based on smaller lattices than
considered here are unlikely to give reliable predictions.Comment: 4 pages, 1 figure; revised version, more data point
Non-invasive mechanical ventilation in patients with diffuse interstitial lung diseases
Phase Separation Models for Cuprate Stripe Arrays
An electronic phase separation model provides a natural explanation for a
large variety of experimental results in the cuprates, including evidence for
both stripes and larger domains, and a termination of the phase separation in
the slightly overdoped regime, when the average hole density equals that on the
charged stripes. Several models are presented for charged stripes, showing how
density waves, superconductivity, and strong correlations compete with quantum
size effects (QSEs) in narrow stripes. The energy bands associated with the
charged stripes develop in the middle of the Mott gap, and the splitting of
these bands can be understood by considering the QSE on a single ladder.Comment: significant revisions: includes island phase, 16 eps figures, revte
Adjuvant mitotane versus surveillance in low-grade, localised adrenocortical carcinoma (ADIUVO): an international, multicentre, open-label, randomised, phase 3 trial and observational study
BACKGROUND: Adjuvant treatment with mitotane is commonly used after resection of adrenocortical carcinoma; however, treatment remains controversial, particularly if risk of recurrence is not high. We aimed to assess the efficacy and safety of adjuvant mitotane compared with surveillance alone following complete tumour resection in patients with adrenocortical carcinoma considered to be at low to intermediate risk of recurrence. METHODS: ADIUVO was a multicentre, open-label, parallel, randomised, phase 3 trial done in 23 centres across seven countries. Patients aged 18 years or older with adrenocortical carcinoma and low to intermediate risk of recurrence (R0, stage I-III, and Ki67 ≤10%) were randomly assigned to adjuvant oral mitotane two or three times daily (the dose was adjusted by the local investigator with the target of reaching and maintaining plasma mitotane concentrations of 14-20 mg/L) for 2 years or surveillance alone. All consecutive patients at 14 study centres fulfilling the eligibility criteria of the ADIUVO trial who refused randomisation and agreed on data collection via the European Network for the Study of Adrenal Tumors adrenocortical carcinoma registry were included prospectively in the ADIUVO Observational study. The primary endpoint was recurrence-free survival, defined as the time from randomisation to the first radiological evidence of recurrence or death from any cause (whichever occurred first), assessed in all randomly assigned patients by intention to treat. Overall survival, defined as time from the date of randomisation to the date of death from any cause, was a secondary endpoint analysed by intention to treat in all randomly assigned patients. Safety was assessed in all patients who adhered to the assigned regimen, which was defined by taking at least one tablet of mitotane in the mitotane group and no mitotane at all in the surveillance group. The ADIUVO trial is registered with ClinicalTrials.gov, NCT00777244, and is now complete. FINDINGS: Between Oct 23, 2008, and Dec 27, 2018, 45 patients were randomly assigned to mitotane and 46 to surveillance alone. Because the study was discontinued prematurely, 5-year recurrence-free and overall survival are reported instead of recurrence-free and overall survival as defined in the protocol. 5-year recurrence-free survival was 79% (95% CI 67-94) in the mitotane group and 75% (63-90) in the surveillance group (hazard ratio 0·74 [95% CI 0·30-1·85]). Two people in the mitotane group and five people in the surveillance group died, and 5-year overall survival was not significantly different (95% [95% CI 89-100] in the mitotane group and 86% [74-100] in the surveillance group). All 42 patients who received mitotane had adverse events, and eight (19%) discontinued treatment. There were no grade 4 adverse events or treatment-related deaths. INTERPRETATION: Adjuvant mitotane might not be indicated in patients with low-grade, localised adrenocortical carcinoma considering the relatively good prognosis of these patients, and no significant improvement in recurrence-free survival and treatment-associated toxicity in the mitotane group. However, the study was discontinued prematurely due to slow recruitment and cannot rule out an efficacy of treatment. FUNDING: AIFA, ENSAT Cancer Health F2-2010-259735 programme, Deutsche Forschungsgemeinschaft, Cancer Research UK, and the French Ministry of Health
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