346 research outputs found
O PROCESSO ELETRÔNICO COMO EFETIVAÇÃO DO DIREITO FUNDAMENTAL DE ACESSO À JUSTIÇA
O propósito deste artigo é apontar o processo eletrônico como instrumento na realização do direito fundamental de acesso à justiça. Não basta a garantia formal. O Estado democrático de direito há de buscar meios de superação dos muitos e variados entraves em seu sistema judicial, para concretizar o ideal de |Justiça acessível para todos. O uso dos recursos eletrônico, de modo a afastar as mazelas do sistema onde “o processo é lento e os procedimentos demasiadamente complexos sem falarmos do, no mínimo, exagerado sistema recursal e impugnativo nacional.” (Gajardoni, Fernando da Fonseca. Técnicas de aceleração do processo/Fernando da Fonseca Gajardoni.- São Paulo: Lemos & Cruz, 2003, pp.15/16)
Food prospects of selenium enriched-Lactobacillus acidophilus CRL 636 and Lactobacillus reuteri CRL 1101
Selenium, which is present as SeCys in selenoproteins, is involved in cancer prevention, thyroid functioning, and pathogen inhibition. Lactobacilli can biotransform inorganic Se into seleno-amino acids. Growth, Se accumulation and seleno-amino acid formation by Lactobacillus acidophilus CRL636 and L. reuteri CRL1101 in a Se-supplemented medium were studied. Moreover, survival of Se-enriched strains to different pH values and bile salts was analyzed. L. acidophilus CRL636 showed low growth rate in the presence of Se while differences were less evident for L. reuteri CRL1101, which displayed higher amounts of intracellular SeCys and SeMet than the CRL636 strain. Interestingly, both lactobacilli could produce Se-nanoparticles. Se-enriched lactobacilli showed lower growth rates than non-Se exposed cells. The adverse effect of bile salts and the ability to survive at pH 4.0 diminished for the Se-enriched L. reuteri strain. The studied lactobacilli could be used as Se-enriched probiotics or as a vehicle for manufacturing Se-containing fermented foods.Fil: Pescuma, Micaela. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; Argentina. Universidad Complutense de Madrid; EspañaFil: Gomez Gomez, Beatríz. Universidad Complutense de Madrid; EspañaFil: Perez Corona, Teresa. Universidad Complutense de Madrid; EspañaFil: Font, Graciela Maria. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; ArgentinaFil: Madrid Albarrn, Yolanda. Universidad Complutense de Madrid; EspañaFil: Mozzi, Fernanda Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucuman. Centro de Referencia Para Lactobacilos; Argentin
Group key exchange protocols withstanding ephemeral-key reveals
When a group key exchange protocol is executed, the session key is typically extracted from two types of secrets; long-term keys (for authentication) and freshly generated (often random) values. The leakage of this latter so-called ephemeral keys has been extensively analyzed in the 2-party case, yet very few works are concerned with it in the group setting. We provide a generic {group key exchange} construction that is strongly secure, meaning that the attacker is allowed to learn both long-term and ephemeral keys (but not both from the same participant, as this would trivially disclose the session key). Our design can be seen as a compiler, in the sense that it builds on a 2-party key exchange protocol which is strongly secure and transforms it into a strongly secure group key exchange protocol by adding only one extra round of communication. When applied to an existing 2-party protocol from Bergsma et al., the result is a 2-round group key exchange protocol which is strongly secure in the standard model, thus yielding the first construction with this property
La planeación urbana y los juegos olímpicos de la Ciudad de México, 1968
Los juegos olímpicos modernos son el evento deportivo más grande e importante a nivel mundial. Las ciudades que han albergado este evento se han enfrentado a diversos retos para brindar una experiencia única, en el que se deben contemplar los espacios requeridos para la infraestructura deportiva y equipamiento necesario.
Los juegos olímpicos de México 1968 marcaron la historia de las olimpiadas al ser el primer país en vías de desarrollo y el primero de Latinoamérica en albergar el evento, así como la primera transmisión a color de los juegos olímpicos en la televisión mundial, por lo que la planeación urbana de la ciudad y la organización de los juegos olímpicos se integraron para dar forma a los proyectos de infraestructura que quedarían para marcar la imagen de la ciudad.
El tema de los juegos olímpicos y la planeación urbana se aborda en este articulo para descubrir parte de los retos que se presentaron en la edición de la olimpiada de México 1968. Se explora cómo es que la preparación y organización de estos eventos masivos impactan en la infraestructura, equipamiento, movilidad y desarrollo urbano de la ciudad sede, y se analiza cómo una planeación adecuada puede tener un efecto positivo en la experiencia del evento y legado que deja en la ciudad a largo plazo.
Este trabajo es un avance en la investigación sobre el tema de la planeación urbana y los juegos olímpicos en las ciudades sede, que se ha logrado a través de la revisión bibliográfica y hemerográfica de temas sobre la ciudad, eventos masivos y juegos olímpicos
Visual thinking como habilidad potenciadora de la gerencia creativa en equipos innovadores
The research focused on designing a visual thinking-based competency model as an enhancer skill of creative management in innovative teams. It can be classified as part of the positivist paradigm with a quantitative focus; it is also explanatory with a non-experimental, cross-cutting, field design. The population was integrated by twelve (12) innovative team members. An 87-item survey was applied, with scale-like response alternatives. This instrument was validated by experts, reliability was determined by a pilot test applied to a fraction of reporting units. The results were analyzed with descriptive statistics building frequency tables, including arithmetic mean and standard deviation, as well as inferential statistics for calculating variance. To establish the degree of association between variables, the Pearson correlation coefficient was used. The results showed that there is an association between visual thinking and creative management, reflecting a considerable correlative coefficient. A management skills model was established based on an emerging theory, which is why we propose that innovative teams must La investigación se orientó a diseñar un modelo de competencias basado en el visual thinking como habilidad potenciadora de la gerencia creativa en equipos innovadores. La investigación se enmarca dentro del paradigma positivista con enfoque cuantitativo. Asimismo, es explicativa con un diseño no experimental, transversal, de campo. La población se integró con doce (12) miembros de equipos innovadores. Se aplicó una encuesta de 87 ítems, con alternativas de respuestas tipo escala. Dicho instrumento fue validado por expertos, la confiabilidad se determinó con una prueba piloto aplicada a una fracción de unidades informantes. Los resultados fueron analizados con estadística descriptiva construyendo tablas de frecuencia, incluyendo media aritmética y desviación estándar, asi como estadística inferencial para calcular la varianza. Para establecer el grado de asociación entre las variables, se utilizó el Coeficiente de Correlación de Pearson. Los resultados arrojaron que existe asociación entre el visual thinking y la gerencia creativa, reflejando un coeficiente correlativo considerable. Se estableció un modelo de competencias gerenciales en base a una teoría emergente, motivo por el cual los equipos innovadores deben trabajar en el fortalecimiento de ambas variables a fin de optimizar la toma de decisiones en los distintos niveles jerárquicos promoviendo la solución de problemas
Variability of blood eosinophil count and prognosis of COPD exacerbations
MPOC; Eosinofília; ExacerbacióEPOC; Eosinofilia; ExacerbaciónCOPD; Eosinophilia; ExacerbationBackground
Eosinophils in peripheral blood are one of the emerging biomarkers in chronic obstructive pulmonary disease (COPD) patients. However, when analysing the relationship between peripheral eosinophilia and COPD prognosis, highly variable results are obtained. The aim of our study is to describe the serum eosinophilia levels in COPD patients and to analyse their relationship to prognosis following hospital admission.
Methods
A prospective observational study was conducted from 1 October 2016 to 1 October 2018 in the following Spanish centres: Salnés County Hospital in Vilagarcía de Arousa, Arquitecto Marcide Hospital in Ferrol and the University Hospital Complex in Santiago de Compostela. The patients were classified using three cut-off points of blood eosinophil count (BEC): 150 cells/µL, 300 cells/µL, and 400 cells/µL; in addition, the peripheral BEC was analysed on admission.
Results
615 patients were included in the study, 86.2% male, mean age 73.9 years, and mean FEV1 52.7%. The mean stay was 8.4 days, and 6% of all patients were readmitted early. No significant relationship was observed between the BEC, neither in the stable phase nor in the acute phase, and hospital stay, readmissions, deaths during admission, the need for intensive care, or the condition of frequent exacerbator.
Conclusion
The results of our study do not seem to support the usefulness of BEC as a COPD biomarker.This paper has not been funded by any project or scholarship
An Innovative AI-based primer design tool for precise and accurate detection of SARS-CoV-2 variants of concern
As the COVID-19 pandemic winds down, it leaves behind the serious concern that future, even more disruptive pandemics may eventually surface. One of the crucial steps in handling the SARS-CoV-2 pandemic was being able to detect the presence of the virus in an accurate and timely manner, to then develop policies counteracting the spread. Nevertheless, as the pandemic evolved, new variants with potentially dangerous mutations appeared. Faced by these developments, it becomes clear that there is a need for fast and reliable techniques to create highly specific molecular tests, able to uniquely identify VOCs. Using an automated pipeline built around evolutionary algorithms, we designed primer sets for SARS-CoV-2 (main lineage) and for VOC, B.1.1.7 (Alpha) and B.1.1.529 (Omicron). Starting from sequences openly available in the GISAID repository, our pipeline was able to deliver the primer sets for the main lineage and each variant in a matter of hours. Preliminary in-silico validation showed that the sequences in the primer sets featured high accuracy. A pilot test in a laboratory setting confirmed the results: the developed primers were favorably compared against existing commercial versions for the main lineage, and the specific versions for the VOCs B.1.1.7 and B.1.1.529 were clinically tested successfully
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