A new bursting X-ray transient: SAX J1750.8-2900

We have analysed in detail the discovery measurements of the X-ray burster SAX J1750.8-2900 by the Wide Field Cameras on board BeppoSAX in spring 1997, at a position ~1.2 degrees off the Galactic Centre. The source was in outburst on March 13th when the first observation started and showed X-ray emission for ~ 2 weeks. A total of 9 bursts were detected, with peak intensities varying from ~ 0.4 to 1.0 Crab in the 2-10 keV range. Most bursts showed a fast rise time (~ 1s), an exponential decay profile with e-folding time of ~ 5s, spectral softening during decay, and a spectrum which is consistent with few keV blackbody radiation. These features identify them as type-I X-ray bursts of thermonuclear origin. The presence of type-I bursts and the source position close to the Galactic Centre favours the classification of this object as a neutron star low mass X-ray binary. X-ray emission from SAX J1750.8-2900 was not detected in the previous and subsequent Galactic bulge monitoring, and the source was never seen bursting again.Comment: 13 pages, 3 Postscript figures, aaspp4 styl

Recurrent very-long type-I X-ray bursts in the low-mass X-ray binary 4U 1636-53

Two flares with a duration of several hours are reported for the low-mass X-ray binary 4U 1636-53. The characteristics of these flares (i.e., decay time scales, spectral softening, fluences) are very similar to the very long type-I X-ray bursts recently found in several other low-mass X-ray binaries, suggesting that the flares in 4U 1636-53 are also very long type-I X-ray bursts. This would make this source the fifth to exhibit this phenomenon and the first one for which multiple bursts have been found. Interestingly, all five sources accrete at approximately 10% of the Eddington mass accretion rate. Although a chance coincidence or a selection effect cannot be ruled-out at present, this correlation is suggestive and might indicate that only at a narrow range of mass accretion rate such very long type-I X-ray bursts can occur.Comment: Accepted for publication in ApJ Letter

Sedimentation and Type I X-ray Bursts at Low Accretion Rates

Neutron stars, with their strong surface gravity, have interestingly short timescales for the sedimentation of heavy elements. Motivated by observations of Type I X-ray bursts from sources with extremely low persistent accretion luminosities, L_X < 10^{36}\usp\ergspersecond (\simeq 0.01\ensuremath{L_{\mathrm{Edd}}}), we study how sedimentation affects the distribution of isotopes and the ignition of H and He in the envelope of an accreting neutron star. For local mass accretion rates \mdot \lesssim 10^{-2}\medd (for which the ignition of H is unstable), where \medd = 8.8\times 10^{4}\nsp\gpscps, the helium and CNO elements sediment out of the accreted fuel before reaching a temperature where H would ignite. Using one-zone calculations of the thermonuclear burning, we find a range of accretion rates for which the unstable H ignition does not trigger unstable He burning. This range depends on the emergent flux from reactions in the deep neutron star crust; for F = 0.1\nsp\MeV(\dot{m}/\mb), the range is 3\times 10^{-3}\medd\lesssim\mdot\lesssim 10^{-2}\medd. We speculate that sources accreting in this range will build up a massive He layer that later produces an energetic and long X-ray burst. At mass accretion rates lower than this range, we find that the H flash leads to a strong mixed H/He flash. Surprisingly, even at accretion rates \mdot \gtrsim 0.1\medd, although the H and He do not completely segregate, the H abundance at the base of the accumulated layer is still reduced. While following the evolution of the X-ray burst is beyond the scope of this introductory paper, we note that the reduced proton-to-seed ratio favors the production of \iso{12}{C}--an important ingredient for subsequent superbursts.Comment: 15 pages, 14 figures, submitted to ApJ, revised versio

Fast X-ray Transients and Their Connection to Gamma-Ray Bursts

Fast X-ray transients (FXTs) with timescales from seconds to hours have been seen by numerous space instruments. We have assembled archival data from Ariel-5, HEAO-1 (A-1 and A-2), WATCH, ROSAT, and Einstein to produce a global fluence-frequency relationship for these events. Fitting the log N-log S distribution over several orders of magnitude to simple power law we find a slope of -1.0. The sources of FXTs are undoubtedly heterogeneous, the -1 power law is an approximate result of the summation of these multiple sources. Two major contributions come from gamma-ray bursts and stellar flares. Extrapolating from the BATSE catalog of GRBs, we find that the fraction of X-ray flashes that can be the X-ray counterparts of gamma-ray bursts is a function of fluence. Certainly most FXTs are not counterparts of standard gamma-ray bursts. The fraction of FXTs from non-GRB sources, such as magnetic stars, is greatest for the faintest FXTs. Our understanding of the FXT phenomenon remains limited and would greatly benefit from a large, homogeneous data set, which requires a wide-field, sensitive instrument.Comment: 36 pages, 8 figure

A Remarkable Three Hour Thermonuclear Burst From 4U 1820-30

We present a detailed observational and theoretical study of a ~3 hr long X-ray burst (the ``super burst'') observed by the Rossi X-ray Timing Explorer (RXTE) from the low mass X-ray binary (LMXB) 4U 1820-30. This is the longest X-ray burst ever observed from this source, and perhaps one of the longest ever observed in great detail from any source. We show that the super burst is thermonuclear in origin. The level of the accretion driven flux as well as the total energy release of ~1.5 x 10^{42} ergs indicate that helium could not be the energy source for the super burst. We outline the physics relevant to carbon production and burning on helium accreting neutron stars and present calculations of the thermal evolution and stability of a carbon layer and show that this process is the most likely explanation for the super burst. We show that for large columns of accreted carbon fuel, a substantial fraction of the energy released in the carbon burning layer is radiated away as neutrinos, and the heat that is conducted from the burning layer in large part flows inward, only to be released on timescales longer than the observed burst. Thus the energy released possibly exceeds that observed in X-rays by more than a factor of ten. Spectral analysis during the super burst reveals the presence of a broad emission line between 5.8 - 6.4 keV and an edge at 8 - 9 keV likely due to reflection of the burst flux from the inner accretion disk in 4U 1820-30. We believe this is the first time such a signature has been unambiguously detected in the spectrum of an X-ray burst.Comment: AASTEX, 44 pages, 14 figures. Accepted for publication in the Astrophysical Journa

Evidence for a Millisecond Pulsar in 4U 1636-53 During a Superburst

We report the discovery with the Proportional Counter Array on board the Rossi X-ray Timing Explorer of highly coherent 582 Hz pulsations during the February 22, 2001 (UT) ``superburst'' from 4U 1636-53. The pulsations are detected during an 800 s interval spanning the flux maximum of the burst. Within this interval the barycentric oscillation frequency increases in a monotonic fashion from 581.89 to 581.93 Hz. The predicted orbital motion of the neutron star during this interval is consistent with such an increase as long as optical maximum corresponds roughly with superior conjunction of V801 Arae, the optical companion to the neutron star in 4U 1636-53. We show that a range of circular orbits with velocity 90 < v sin i < 175 km/s and fractional phase 0.336 > p > 0.277 for the neutron star can provide an excellent description of the frequency and phase evolution. The average pulse profile is sinusoidal and the time averaged pulsation amplitude, as inferred from the half amplitude of the sinusoid is 1%, smaller than typical for burst oscillations observed in normal thermonuclear bursts. We do not detect any higher harmonics nor the putative subharmonic near 290 Hz. The 90% upper limits on signal amplitude at the subharmonic and first harmonic are 0.1% and 0.06%, respectively. The coherent pulsation provides compelling evidence for a rapidly rotating neutron star in 4U 1636-53, and further supports the connection of burst oscillation frequencies with the spin frequencies of neutron stars. Our results provide further evidence that some millisecond pulsars are spun up via accretion in LMXBs. We also discuss the implications of our orbital velocity constraint for the masses of the components of 4U 1636-53.Comment: 27 pages, 9 figures, AASTeX, accepted for publication in the Astrophysical Journa

E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis.

In breast cancer, inactivating point mutations in the E-cadherin gene are frequently found in invasive lobular carcinoma (ILC) but never in invasive ductal carcinoma (IDC). Lobular carcinoma in situ (LCIS) adjacent to ILC has previously been shown to lack E-cadherin expression, but whether LCIS without adjacent invasive carcinoma also lacks E-cadherin expression and whether the gene mutations present in ILC are already present in LCIS is not known. We report here that E-cadherin expression is absent in six cases of LCIS and present in 150 cases of ductal carcinoma in situ (DCIS), both without an adjacent invasive component. Furthermore, using mutation analysis, we could demonstrate the presence of the same truncating mutations and loss of heterozygosity (LOH) of the wild-type E-cadherin in the LCIS component and in the adjacent ILC. Our results indicate that E-cadherin is a very early target gene in lobular breast carcinogenesis and plays a tumour-suppressive role, additional to the previously suggested invasion-suppressive role