19 research outputs found

    Improving public sector performance: the power of implementing corporate governance

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    The concept of corporate governance of public entities is evolving. Corporate governance in public institutions, as a method of management and control, requires clear rules and principles of integrity, transparency and accountability, well-defined risk management and control mechanisms, elements that are essential for achieving public entities’ goal, which means meeting public needs. Corporate governance is a process through which management monitors and maintains a corporation’s compliance with laws and regulations. Is it necessary to use corporate governance in public entities? Can it reduce expenditure or budget deficits, ensuring an efficient use of public funds? Can it eliminate corruption and improve the performance of public entities? The purpose of this study is to carry out an academic analysis of the evolution of the corporate governance in public entities and to highlight its effectiveness, through principles that encourage better decision-making and resource efficiency. The applied methodology involves focusing on the in-depth study of the subject using the analytical method. Moreover, the study draws comparisons of different models on the aspects researched, using comparative analysis. In conclusion, good corporate governance is essential for any organization to ensure the sustainability of its resources and operations, with a direct effect on the entity’s performance

    A note on the QFT randomness spectral test a new approach of DST

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    Quantum computers provide a new way of solving problems even in cryptography in which digital signature make an important role. In this paper, we describe a comparison between the spectral test in classical mode and quantum mode through Fourier Transform. A comparison of the results in the two cases was made. Applications of the proposed techniques are from the field of statistical testing of the pseudorandom bit generators used for cryptographic applications. The proposed statistical test is an extension of the Discrete Fourier Transform statistical test proposed in NIST SP 800-22

    Phytocompounds Targeting Cancer Angiogenesis Using the Chorioallantoic Membrane Assay

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    Cancer is the second cause of mortality worldwide. Angiogenesis is an important process involved in the growth of primary tumors and metastasis. New approaches for controlling the cancer progression and invasiveness can be addressed by limiting the angiogenesis process. An increasingly large number of natural compounds are evaluated as angiogenesis inhibitors. The chorioallantoic membrane (CAM) assay represents an in vivo attractive experimental model for cancer and angiogenesis studies as prescreening to the murine models. Since the discovery of tumor angiogenesis, the CAM has been intensively used in cancer research. The advantages of this in vivo technique are in terms of low time-consuming, costs, and a lower number of sacrificed animals. Currently, a great number of natural compounds are being investigated for their effectiveness in controlling tumor angiogenesis. Potential reducing of angiogenesis has been investigated by our group for pentacyclic triterpenes, in various formulations, and differences in their mechanism were registered. This chapter aims to give an overview on a number of phytocompounds investigated using in vitro, murine models and the chorioallantoic membrane assay as well as to emphasize the use of CAM assay in the study of natural compounds with potential effects in malignancies

    Carbamazepine-induced DRESS syndrome: a case report

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    Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening, idiosyncratic, acute adverse drug reaction. Fever, morbilliform cutaneous eruption, and eosinophilia are essential features for the diagnosis of this syndrome, along with significant multisystem involvement, hepatitis being the most common, followed by nephritis. The pathogenesis of DRESS syndrome is not yet fully understood. Several hypotheses have been proposed which support the involvement of an intricate interplay of multiple factors. We report a clinical case of DRESS syndrome with renal injury, induced by carbamazepine, in a patient with alcohol abstinence syndrome. In order to define the case, the RegiSCAR score and the Japanese Group score, used in the diagnosis of drug-induced hypersensitivity, were applied. DRESS syndrome is a potentially fatal disease, with a mortality that can reach up to 40% of cases. This condition endangers the patient\u27s life by affecting the internal organs, mainly the liver, kidneys, heart, and lungs. Our case attempts to increase awareness among physicians about this serious disease and the importance of early diagnosis, especially since carbamazepine is a commonly used anticonvulsant drug

    AFM Characterization of Temperature Effect on the SU-8 Mechanical and Tribological Properties

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    This study presents the effect of temperature on the mechanical and tribological properties of SU-8 polymer. The temperature of investigated samples increasing during testing and the variation of mechanical and tribological properties were monitored. The samples for tests were SU-8 hard baked at different temperatures. The hard bake temperature changes the mechanical and tribological properties of polymers. The aim of this research work is the reliability design improvement of SU-8 microstructures from electro-thermally actuated devices where a thermal gradient produces the softening and modification of SU-8 behavior. As a function of the hard baked temperature, different mechanical and tribological properties were experimentally determined using the atomic force microscopy (AFM) technique. The mechanical properties of interest are the modulus of elasticity and hardness. The investigated tribological properties involve the adhesion and friction forces. The modulus of elasticity and hardness decrease if the operating temperature increases based on the thermal relaxation of material and their viscoelastic behavior. The adhesion force between AFM tip and investigated samples increases if the operating temperature increases, respectively. The same evolution was experimentally observed in the case of friction force. Moreover, for the same testing temperature, the modulus of elasticity and hardness increase, and the adhesion and friction forces decrease if the SU-8 is hard baked at high temperature

    Humidity influence on the adhesion of SU-8 polymer from MEMS applications

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    In this paper, the adhesion behaviors of SU-8 polymer thin film from MEMS application were investigated as a function of relative humidity. The adhesion test between the AFM tip and SU-8 polymer have been extensively studied using the atomic force microscope (AFM), for a relative humidity (RH) varying between 20 and 90%. The samples for tests are SU-8 polymers hard baked at different temperatures. The hard bake temperature changes the tribo-mechanical properties of polymers. The paper reports the measurements and the modeling of adhesion forces versus humidity in controlled ranges between 20 to 90%RH. To investigate the effect of relative humidity on adhesion for SU-8 polymer hard baked we used an analytical method which encompasses the effect of capillarity as well as the solid-to-solid interaction. While the capillary force expression is considered to be the sum of the superficial tension and the Laplace force for the solid-solid interaction is expressed by the Derjagin, Muller and Toropov (DMT) model of solids adhesion. The analytical results obtained are in accordance with those obtained experimentally

    Humidity influence on the adhesion of SU-8 polymer from MEMS applications

    No full text
    In this paper, the adhesion behaviors of SU-8 polymer thin film from MEMS application were investigated as a function of relative humidity. The adhesion test between the AFM tip and SU-8 polymer have been extensively studied using the atomic force microscope (AFM), for a relative humidity (RH) varying between 20 and 90%. The samples for tests are SU-8 polymers hard baked at different temperatures. The hard bake temperature changes the tribo-mechanical properties of polymers. The paper reports the measurements and the modeling of adhesion forces versus humidity in controlled ranges between 20 to 90%RH. To investigate the effect of relative humidity on adhesion for SU-8 polymer hard baked we used an analytical method which encompasses the effect of capillarity as well as the solid-to-solid interaction. While the capillary force expression is considered to be the sum of the superficial tension and the Laplace force for the solid-solid interaction is expressed by the Derjagin, Muller and Toropov (DMT) model of solids adhesion. The analytical results obtained are in accordance with those obtained experimentally
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