Going from A to B : the safety of incompatible group A plasma for emergency release in trauma and massive transfusion patients

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108097/1/trf12730.pd

A hot option for a cold subject

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91340/1/j.1537-2995.2011.03474.x.pd

Inverse expression of P k and Luke blood group antigens on human RBCs

Luke (LKE) is a high-frequency RBC antigen, related to the P blood group system. A LKE-negative phenotype is found in 1 to 2 percent of donors and may be associated with increased P k . Because P k and similar glycolipids are receptors for shiga toxin on cell membranes, a LKE-negative phenotype could have implications for infections by Shigella dysenteriae and enterohemorrhagic Escherichia coli . STUDY DESIGN AND METHODS: Volunteer donors (n = 257) were serologically typed for LKE with a LKE MoAb, MC813-70. LKE-strong-positive, LKE-weak-positive and LKE-negative RBCs were analyzed for P k , P, LKE, and shiga toxin binding by immunofluorescence flow cytometry, high-performance thin-layer chromatography, scanning densitometry, and high-performance thin-layer chromatography immunostaining. RESULTS: Among Iowa donors, 78.6 percent were LKE-strong-positive, 20.2 percent were LKE-weak-positive, and 1.2 percent were LKE-negative. There was an inverse expression of P k and LKE on RBCs. P k expression was increased on LKE-negative RBCs and was associated with increased shiga toxin binding. A LKE-active glycolipid was identified in the ganglioside fraction of LKE-strong-positive RBCs. CONCLUSION: A LKE-negative phenotype is associated with increased expression of P k on RBCs. Differences in P k and LKE expression may play a role in host susceptibility to infection with S. dysenteriae and E. coli .Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73915/1/j.1537-2995.2001.41070898.x.pd

Another case of acute cardiopulmonary toxicity with cord blood infusion: is dextran the culprit?

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/89502/1/j.1537-2995.2011.03424.x.pd

Red blood cell transfusion in palliative care: what are we doing and why are we doing it?

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141052/1/trf14437.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141052/2/trf14437_am.pd

Development of trauma informed mental health assessment guidelines for use in a local Single Point of Access Service (SPoA)

Special Edition #400WORDS: CHIEF NURSE RESEARCH FELLOWSHIP EVIDENCE IMPLEMENTATION PROJECT

ABO‐associated antibody‐mediated rejection following A2B‐to‐B renal transplantation and successful treatment with therapeutic plasma exchange

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/149287/1/trf15201_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/149287/2/trf15201.pd

An imPRESsive mimic

Received for publication April 22, 2009; revision received June 18, 2009; and accepted June 19, 2009.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/78628/1/j.1537-2995.2009.02362.x.pd

An evaluation of storage time for dithiothreitol‐treated reagent cells

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138313/1/trf14244.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/138313/2/trf14244_am.pd