187 research outputs found
Adaptive Governance: An Introduction and Implications for Public Policy
Adaptive governance is a concept from institutional theory that deals with the evolution of institutions for the management of shared assets, particularly common pool resources and other forms of natural capital. This paper is the first of a set of four papers on adaptive governance, providing a brief overview of the history of the concept, the distinguishing features of the literature, and key insights provided for economists and policy advisors. We argue that adaptive governance provides an interesting lens for examining the political economy of policy responses akin to the concept of market failure within economics, but applied to wider processes of social learning and collective choice, including collective choices about the scope and structure of institutions that govern lower level choices by individuals and organizations.adaptive governance, public policy, common pool resources, natural resource management, wicked problems, Institutional and Behavioral Economics,
Exploration of community neuropsychological rehabilitation following acquired brain injury: psychosocial outcomes and narratives of identity
Introduction: High intensity holistic neuropsychological rehabilitation is the most
evidenced-based intervention for post-acute ABI rehabilitation. However, the
majority of the current evidence has examined inpatient or residential treatment
contexts. Little is known about the efficacy of community neuropsychological
rehabilitation interventions or the clinical validity of both high and low intensity forms
of rehabilitation in a community rehabilitation setting. The systematic review
synthesises the existing evidence for community-based holistic neuropsychological
rehabilitation and its psycho-social outcomes.
Changes in self and group identity have been suggested to underpin evidence-based
neuropsychological rehabilitation. However, little is known about how these
processes of identity change following ABI and throughout the rehabilitation process.
The empirical study explores key turning points in the self-narratives of individuals
with ABI in order to better understand the clinical and contextual factors which
influence their rehabilitation.
Methods: A search was conducted of Embase, Embase classic, Medline and PsycInfo.
Studies were assessed for risk of bias and outcomes were synthesised following the
PRISMA guidelines for systematic reviews.
A ‘holistic-content’ narrative methodology was then employed to explore the post-acute
adjustment and rehabilitation narratives of 11 individuals following ABI. Three-dimensional
analysis of interaction, continuity and situation was used to examine
individuals’ personal reflections of identity changes across their illness experience;
and cross-case comparisons identified common transformational themes.
Results: 15 studies were included in the review. Two distinct levels of intervention
intensity were identified: high intensity interventions delivered multiple days per
week, and low intensity interventions delivered only once a week. A synthesis of nine
studies examining high intensity neuropsychological rehabilitation found evidence
that these interventions can improve psychological wellbeing and enhance
community integration following ABI when delivered on an outpatient basis. A
synthesis of six low intensity interventions found limited evidence that they can lead
to improved psycho-social outcomes when structure to target specific difficulties, and
evidence that they can effectively support the achievement of individual patient
goals.
Following the analysis of ABI survivor narratives, themes of ‘Rehabilitation focus and
psychological distress’, ‘Reclaiming efficacy in valued life domains’, and ‘Social comparisons:
inclusion and exclusion’ were identified; each representing a continuum of personal and
social understanding along which people moved during their rehabilitation.
Conclusions: The systematic review suggested that high intensity forms of outpatient
neuropsychological rehabilitation are effective at improving psycho-social outcomes. Low
intensity forms of outpatient neuropsychological rehabilitation appear to offer a less
favourable alternative to supporting psycho-social adjustment in the community at present.
Findings from the empirical paper suggest that illness identity may be co-constructed in the
context of early treatment experiences, and appears to influence post-acute rehabilitation
focus; and that pre-injury values and self-identity guided participant approaches to re-establishing
self-efficacy. These processes were supported by clinical, social and group
interactions
Improving Family Engagement in an Adult Inpatient Mental Health Service using an Action Research Framework
Family involvement in mental health treatment has been shown to improve outcomes for service users. This project used a whole system-focused action research framework and involved service users, family members and healthcare professionals to develop ways to improve family engagement in an adult inpatient mental health service. Focus groups were conducted with two service users, two family members and four healthcare professionals to discuss their experiences of family involvement and develop initial ideas. A problem-solving group, involving service users, family members and professionals, was used to develop the solutions. The project identified context-specific solutions to improve family engagement, which included specific training for professionals working on the inpatient wards, questionnaires to facilitate conversations with families, and sharing information about mental health and the inpatient mental health service with families. These may be helpful for other adult inpatient services.</p
Apathy and its response to antipsychotic review and non-pharmacological interventions in people with dementia living in nursing homes : WHELD, A factorial cluster randomised controlled trial
Objectives: Apathy is common, impactful, and difficult to manage in people with dementia. We evaluated the efficacy of non-pharmacological interventions, exercise and social interaction, in combination with antipsychotic review, to reduce apathy in people with dementia living in nursing homes in a cluster randomised controlled trial (RCT). Methods: Well-being and health for people with dementia (WHELD) programme included a 2X2X2 factorial cluster RCT involving people with dementia living in 16 nursing homes in UK. All homes received training in person-centred care, and were randomised to receive antipsychotic review, social interaction, and exercise, either alone or in combinations. Apathy was one of the secondary outcomes of the WHELD trial, and it was measured by the Neuropsychiatric Inventory-nursing home version at baseline and nine months (N=273). We employed multilevel mixed effects linear regression models to assess the impact of the interventions on apathy. Results: Prevalence of apathy was 44.0% (n=120; 95% CI 38.1-49.9%) at baseline. Severity of apathy had significant positive correlations with dementia severity, neuropsychiatric symptoms, depressive symptoms, agitation, and the needs of the people with dementia (p<0.001). Antipsychotic review reduced antipsychotic use, but it significantly increased apathy (β=5.37; SE=0.91; p<0.001). However, antipsychotic review in combination with either social interaction (β=-5.84; SE=1.15; p<0.001) or exercise (β=-7.54; SE=0.93; p<0.001) significantly reduced apathy. Conclusions: Antipsychotic review can play a significant role in improving apathy in people with dementia living in nursing homes, when combined with psychosocial interventions such as social interaction and exercise. Guidance must be adapted to reflect this subtlety in care
Coronary artery height differences and their effect on fractional flow reserve
Background: Fractional flow reserve (FFR) uses pressure-based measurements to assess the severityof a coronary stenosis. Distal pressure (Pd) is often at a different vertical height to that of the proximalaortic pressure (Pa). The difference in pressure between Pd and Pa due to hydrostatic pressure, mayimpact FFR calculation.Methods: One hundred computed tomography coronary angiographies were used to measure heightdifferences between the coronary ostia and points in the coronary tree. Mean heights were used to calculate the hydrostatic pressure effect in each artery, using a correction factor of 0.8 mmHg/cm. Thiswas tested in a simulation of intermediate coronary stenosis to give the “corrected FFR” (cFFR) andpercentage of values, which crossed a threshold of 0.8.Results: The mean height from coronary ostium to distal left anterior descending (LAD) was +5.26 cm,distal circumflex (Cx) –3.35 cm, distal right coronary artery-posterior left ventricular artery (RCA-PLV)–5.74 cm and distal RCA-posterior descending artery (PDA) +1.83 cm. For LAD, correction resulted in a mean change in FFR of +0.042, –0.027 in the Cx, –0.046 in the PLV and +0.015 in the PDA. Using 200 random FFR values between 0.75 and 0.85, the resulting cFFR crossed the clinical treatmentthreshold of 0.8 in 43% of LAD, 27% of Cx, 47% of PLV and 15% of PDA cases.Conclusions: There are significant vertical height differences between the distal artery (Pd) and its point of normalization (Pa). This is likely to have a modest effect on FFR, and correcting for this results in a proportion of values crossing treatment thresholds. Operators should be mindful of this phenomenon when interpreting FFR values
Mechanisms of Esophago-Pharyngeal Acid Regurgitation in Human Subjects
Esophago-pharyngeal regurgitation is implicated in various otolaryngologic and respiratory disorders. The pathophysiological mechanisms causing regurgitation are still largely unknown
The Astropy Problem
The Astropy Project (http://astropy.org) is, in its own words, "a community
effort to develop a single core package for Astronomy in Python and foster
interoperability between Python astronomy packages." For five years this
project has been managed, written, and operated as a grassroots,
self-organized, almost entirely volunteer effort while the software is used by
the majority of the astronomical community. Despite this, the project has
always been and remains to this day effectively unfunded. Further, contributors
receive little or no formal recognition for creating and supporting what is now
critical software. This paper explores the problem in detail, outlines possible
solutions to correct this, and presents a few suggestions on how to address the
sustainability of general purpose astronomical software
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