Install America (or wherever you are)

The following project was developed as a requirement in an Art Education preparation course at the University of Northern Colorado. The program is strong in traditional academic skill building as are many of the k-12 art programs in the area. Teacher candidates must take courses in drawing, painting, ceramics, sculpture etc.https://scholarscompass.vcu.edu/cstae_resource_higher_education/1001/thumbnail.jp

The α\alpha-kk-NNNN regression for compositional data

Compositional data arise in many real-life applications and versatile methods for properly analyzing this type of data in the regression context are needed. This paper, through use of the $\alpha$-transformation, extends the classical $k$-$NN$ regression to what is termed $\alpha$-$k$-$NN$ regression, yielding a highly flexible non-parametric regression model for compositional data. Unlike many of the recommended regression models for compositional data, zeros values (which commonly occur in practice) are not problematic and they can be incorporated into the proposed model without modification. Extensive simulation studies and real-life data analyses highlight the advantage of using $\alpha$-$k$-$NN$ regression for complex relationships between the compositional response data and Euclidean predictor variables. Both suggest that $\alpha$-$k$-$NN$ regression can lead to more accurate predictions compared to current regression models which assume a, sometimes restrictive, parametric relationship with the predictor variables. In addition, the proposed regression enjoys a high computational efficiency rendering it highly attractive for use with large scale, massive, or big data.Comment: This is a preprin

The Health Status and Unique Health Challenges of Rural Older Adults in California

Examines the demographics, health, and levels of physical activity and food insecurity of rural seniors compared with those of urban and suburban seniors. Outlines environmental and social risk factors that require context-specific policies and programs

Plasma ATP concentration and venous oxygen content in the forearm during dynamic handgrip exercise

Background It has been proposed that adenosine triphosphate (ATP) released from red blood cells (RBCs) may contribute to the tight coupling between blood flow and oxygen demand in contracting skeletal muscle. To determine whether ATP may contribute to the vasodilatory response to exercise in the forearm, we measured arterialised and venous plasma ATP concentration and venous oxygen content in 10 healthy young males at rest, and at 30 and 180 seconds during dynamic handgrip exercise at 45% of maximum voluntary contraction (MVC). Results Venous plasma ATP concentration was elevated above rest after 30 seconds of exercise (P < 0.05), and remained at this higher level 180 seconds into exercise (P < 0.05 versus rest). The increase in ATP was mirrored by a decrease in venous oxygen content. While there was no significant relationship between ATP concentration and venous oxygen content at 30 seconds of exercise, they were moderately and inversely correlated at 180 seconds of exercise (r = -0.651, P = 0.021). Arterial ATP concentration remained unchanged throughout exercise, resulting in an increase in the venous-arterial ATP difference. Conclusions Collectively these results indicate that ATP in the plasma originated from the muscle microcirculation, and are consistent with the notion that deoxygenation of the blood perfusing the muscle acts as a stimulus for ATP release. That ATP concentration was elevated just 30 seconds after the onset of exercise also suggests that ATP may be a contributing factor to the blood flow response in the transition from rest to steady state exercise

Clinical and virologic efficacy of herpes simplex virus type 2 suppression by acyclovir in a multicontinent clinical trial.

Acyclovir suppressive therapy (400 mg twice daily) reduces herpes simplex virus (HSV) type 2-associated genital ulcer disease and lesional HSV shedding. In an international trial of acyclovir for suppression of HSV type 2 to prevent human immunodeficiency virus (HIV) acquisition (HIV Prevention Trials Network 039), acyclovir had a smaller effect on the frequency of genital ulcer disease as well as a smaller effect on the frequency and quantity of lesional HSV DNA in African women and Peruvian men, compared with its effects in men in the United States. The observed regional variation in the clinical and virologic efficacy of acyclovir for HSV suppression warrants further evaluation of determinants of responses to acyclovir. (ClinicalTrials.gov identifier: NCT00076232.)

The Ursinus Weekly, February 26, 1951

Senior musical to revive era of flapper, prohibition • IRC to discuss U.S. foreign policy • Food council conducts review of situation here • Big top chosen theme of freshman dance, March 2 • Book review given • Quartet sings to bank cashier, endorses faulty check vocally • Time features successful industrialist, E. D. Bransome, former student here • Play books in Library • 1936 Ursinus graduate attains USAF honors • Campus March of dimes nets $34 total; Maples heads list • Board discloses interest in armed service units • Audience to enter mood of Tuesday\u27s suspenseful drama • Summer students asked to sign up • 29 delegates attend Philadelphia debate • Hess enumerates ways of using law training • WAA abandons plans for annual minstrel show; To sell socks • FTA considers courses • Editorial: An Ursinus community chest? • Reflections on mealtime • Weekly asks: What do you think of having an ROTC unit at a church-related college? • Canine King Henry lounges on campus, carries schedule of dog-ology, barking • Dr. J. H. A. Bomberger, first Ursinus president, led college through difficulties of early years • Juniata, too, has mystery balls • Campus agents promote local sale of cigarettes • Glenwood Memorial recalls dim past, puzzles over current popular usage • George Gay, Ursinus immortal, had brilliant grid career • Bucknell Bisons trounce matmen 29-5 as Helfferich posts lone win for locals • Battling Bruins rebound to edge Dragons 74-70 • Bryn Mawr bests swimmers, 19-18 • Belles post second victory of season • Bears rout cadets 85-71 as league race tightens • Brodbeck I clinches tie in intramurals • Y activities to center around Wednesday night fireside chats • Lintner heads Red Cross • 3 French Club members attend dinner in Philadelphia church • Dr. Allan Rice to address Lions on Atlantic Union • Juniors name committee heads • Dolman reads humorous work on Education of Hyman Kaplanhttps://digitalcommons.ursinus.edu/weekly/1560/thumbnail.jp

Estimating PMTCT's Impact on Heterosexual HIV Transmission: A Mathematical Modeling Analysis

Introduction Prevention of mother-to-child HIV transmission (PMTCT) strategies include combined short-course antiretrovirals during pregnancy (Option A), triple-drug antiretroviral treament (ART) during pregnancy and breastfeeding (Option B), or lifelong ART (Option B+). The WHO also recommends ART for HIV treatment and prevention of sexual transmission of HIV. The impact of PMTCT strategies on prevention of sexual HIV transmission of HIV is not known. We estimated the population-level impact of PMTCT interventions on heterosexual HIV transmission in southwestern Uganda and KwaZulu-Natal, South Africa, two regions with different HIV prevalence and fertility rates. Materials and Methods We constructed and validated dynamic, stochastic, network-based HIV transmission models for each region. PMTCT Options A, B, and B+ were simulated over ten years under three scenarios: 1) current ART and PMTCT coverage, 2) current ART and high PMTCT coverage, and 3) high ART and PMTCT coverage. We compared adult HIV incidence after ten years of each intervention to Option A (and current ART) at current coverage. Results At current coverage, Options B and B+ reduced heterosexual HIV incidence by about 5% and 15%, respectively, in both countries. With current ART and high PMTCT coverage, Option B+ reduced HIV incidence by 35% in Uganda and 19% in South Africa, while Option B had smaller, but meaningful, reductions. The greatest reductions in HIV incidence were achieved with high ART and PMTCT coverage. In this scenario, all PMTCT strategies yielded similar results. Discussion Implementation of Options B/B+ reduces adult HIV incidence, with greater effect (relative to Option A at current levels) in Uganda than South Africa. These results are likely driven by Uganda’s higher fertility rates