9 research outputs found
Training Interior Designers To Project Feasibility Studies
The proactive economic and financial sustainability estimation for the Interior design has to be centered on an organized structure of knowledge in the project planning and development. This need arises, on one side, in the light of the consciousness that the Project assessment science works in the hard field of the ex-ante calculation of prices. On the other hand, it is linked to the necessity for a shift to a practical estimation approach, that should be effectively integrated even in the teaching activities, to be better prepared to the challenges they will meet in their future professional field. The paper will revolve around the need of introducing a structured system of principles in this field, as the valuation process is a key element for the risk management and it is important to apply internationally recognized valuation standards
Doing Something Scenario: Teaching Students an Incremental Approach to Design Strategies for Developing Countries
The 90% of the global population growth in the next 30 years will happen in developing countries, where the urban population rise will create increasing issues related to informal settlements and growing inequality. Improving the health conditions of the built environment and reducing the related risks will be a crucial challenge for future urban professionals. This paper is aimed at describing a learning experience built as a workshop for students, in which they designed a social facility modular system for developing countries, inspired by the organic and hypogeum architecture principles. The result is a list of guidelines for the design of similar functions, that should help a conscious construction process to reach some fundamental sustainability goals
Design and manufacturing of a compact two-mirror system for multispectral imaging applications
Spectral imaging systems drive the development of remote sensing applications. The possibility to combine integrated multispectral sensors to compact, broadband and wide field optical systems is highly advantageous in terms of reliability, portability, and cost reduction. On the other hand, such optical systems often rely on the
feasibility of demanding optical components, as of strongly aspheric optics. The activity of manufacturing and
metrological testing of such optics is crucial for the achievement of the whole project. In this paper, we present the design of a compact two-mirror system and the manufacturing of the strongly aspheric primary mirror
Sustained release from injectable composite gels loaded with silver nanowires designed to combat bacterial resistance in bone regeneration applications
One-dimensional nanostructures, such as silver nanowires (AgNWs), have attracted considerable attention owing to their outstanding electrical, thermal and antimicrobial properties. However, their application in the prevention of infections linked to bone tissue regeneration intervention has not yet been explored. Here we report on the development of an innovative scaffold prepared from chitosan, composite hydroxyapatite and AgNWs (CS-HACS-AgNWs) having both bioactive and antibacterial properties. In vitro results highlighted the antibacterial potential of AgNWs against both gram-positive and gram-negative bacteria. The CS-HACS-AgNWs composite scaffold demonstrated suitable Ca/P deposition, improved gel strength, reduced gelation time, and sustained Ag+ release within therapeutic concentrations. Antibacterial studies showed that the composite formulation was capable of inhibiting bacterial growth in suspension, and able to completely prevent biofilm formation on the scaffold in the presence of resistant strains. The hydrogels were also shown to be biocompatible, allowing cell proliferation. In summary, the developed CS-HACS-AgNWs composite hydrogels demonstrated significant potential as a scaffold material to be employed in bone regenerative medicine, as they present enhanced mechanical strength combined with the ability to allow calcium salts deposition, while efficiently decreasing the risk of infections. The results presented justify further investigations into the potential clinical applications of these materials
Silicon pore optics mirror modules for inner and outer radii
Athena (Advanced Telescope for High Energy Astrophysics) is an x-ray observatory using a Silicon Pore Optics telescope and was selected as ESA's second L-class science mission for a launch in 2028. The x-ray telescope consists of several hundreds of mirror modules distributed over about 15-20 radial rings. The radius of curvature and the module sizes vary among the different radial positions of the rings resulting in different technical challenges for mirror modules for inner and outer radii. We present first results of demonstrating Silicon Pore Optics for the extreme radial positions of the Athena telescope. For the inner most radii (0.25 m) a new mirror plate design is shown which overcomes the challenges of larger curvatures, higher stress values and bigger plates. Preliminary designs for the mounting system and its mechanical properties are discussed for mirror modules covering all other radial positions up to the most outer radius of the Athena telescope
Project assessment and economic and financial sustainability determination for the Interior design
The proactive economic and financial sustainability estimation for the Interior design has to be centered on an organized structure of knowledge in the project planning and development, in the light of the consciousness that the Project assessment science works in the hard field of the ex-ante calculation of prices. The paper will revolve around the need of introducing a structured system of principles in this field, as the valuation process is a key element for the risk management and it is important to apply internationally recognized valuation standards
TEACHING ITALIAN STYLE TO INTERNATIONAL INTERIOR DESIGNERS
Can you teach Interior Designers how their creative process can benefit from being contaminated by the quality and excellence of the Italian Style attitude? The course “Where Interior Design meets Fashion. Italian Style” is meant to teach learners (students and professionals from all over the world) the distinguishing features of the charming and classy mood that defines one of the most famous stylishness examples in the world. At first glance, Fashion and Interior Design might not seem to have much in common. However, the boundaries blur when the two industries cooperate – and this is happening more and more. People that appreciate a cultured style, that goes beyond the typical fashion items, can also find fully structured lines and collections of home products from the main Fashion Brands. This is not a new experience, since Fashion and Interior Design have been mutually influencing each other for centuries. The basic idea is, then, that innovative teaching techniques, in this field, can help designers to learn and implement the main characters of a stylistic feel, and apply them into their professional layouts. The main approach is, then, teaching learners through a learning by doing/thinking/loving technique, in a proactive design exercise of role playing, in which they will be Interior Designers for a famous Italian Fashion Brand of their choice
Impact of treatment in long-term survival patients with follicular lymphoma: A Spanish Lymphoma Oncology Group registry
Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCORD-3): analysis of individual data from 258 cancer registries in 61 countries
Background:
Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0–14 years) and adults (aged 15–99 years) diagnosed with a haematological malignancy during 2000–14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0–24 years).
Methods:
We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3 that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0–14 years), adolescents (15–19 years), and young adults (20–24 years). We categorised leukaemia subtypes according to the International Classification of Childhood Cancer (ICCC-3), updated with International Classification of Diseases for Oncology, third edition (ICD-O-3) codes. We estimated 5-year net survival by age and morphology, with 95% CIs, using the non-parametric Pohar-Perme estimator. To control for background mortality, we used life tables by country or region, single year of age, single calendar year and sex, and, where possible, by race or ethnicity. All-age survival estimates were standardised to the marginal distribution of young people with leukaemia included in the analysis.
Findings:
164 563 young people were included in this analysis: 121 328 (73·7%) children, 22 963 (14·0%) adolescents, and 20 272 (12·3%) young adults. In 2010–14, the most common subtypes were lymphoid leukaemia (28 205 [68·2%] patients) and acute myeloid leukaemia (7863 [19·0%] patients). Age-standardised 5-year net survival in children, adolescents, and young adults for all leukaemias combined during 2010–14 varied widely, ranging from 46% in Mexico to more than 85% in Canada, Cyprus, Belgium, Denmark, Finland, and Australia. Individuals with lymphoid leukaemia had better age-standardised survival (from 43% in Ecuador to ≥80% in parts of Europe, North America, Oceania, and Asia) than those with acute myeloid leukaemia (from 32% in Peru to ≥70% in most high-income countries in Europe, North America, and Oceania). Throughout 2000–14, survival from all leukaemias combined remained consistently higher for children than adolescents and young adults, and minimal improvement was seen for adolescents and young adults in most countries.
Interpretation:
This study offers the first worldwide picture of population-based survival from leukaemia in children, adolescents, and young adults. Adolescents and young adults diagnosed with leukaemia continue to have lower survival than children. Trends in survival from leukaemia for adolescents and young adults are important indicators of the quality of cancer management in this age group