Measurement of a Structured Backflow in an Open Small Channel Induced by Surface-Tension Gradients

We present experiments in which the laterally confined flow of a surfactant film driven by controlled surface tension gradients causes the subtended liquid layer to self-organize into an inner upstream microduct surrounded by the downstream flow. The anomalous interfacial flow profiles and the concomitant backflow are a result of the feedback between two-dimensional and three-dimensional microfluidics realized during flow in open microchannels. Bulk and surface particle image velocimetry data combined with an interfacial hydrodynamics model explain the dependence of the observed phenomena on channel geometry

Stability of core/shell quantum dots-role of pH and small organic ligands

The improvement of knowledge about the toxicity and even processability, and stability of quantum dots (QD) requires the understanding of the relationship between the QD binding head group, surface structure, and interligand interaction. The scanned stripping chronopotentiometry and absence of gradients and Nernstian equilibrium stripping techniques were used to determine the concentration of Cd dissolved from a polyacrylate-stabilized CdTe/CdS QD. The effects of various concentrations of small organic ligands such as citric acid, glycine, and histidine and the roles of pH (4.5–8.5) and exposure time (0–48 h) were evaluated. The highest QD dissolution was obtained at the more acidic pH in absence of the ligands (52 %) a result of the CdS shell solubility. At pH 8.5 the largest PAA ability to complex the dissolved Cd leads to a further QD solubility until the equilibrium is reached (24 % of dissolved Cd vs.4 % at pH 6.0). The citric acid presence resulted in greater QD dissolution, whereas glycine, an amino acid, acts against QD dissolution. Surprisingly, the presence of histidine, an amino acid with an imidazole functional group, leads to the formation of much strong Cd complexes over time, which may be non-labile, inducing variations in the local environment of the QD surface

The search campaign to identify and Image the Philae Lander on the surface of comet 67P/Churyumov-Gerasimenko

On the 12th of November 2014, the Rosetta Philae Lander descended to make the first soft touchdown on the surface of a comet – comet 67P/Churyumov- Gerasimenko. That soft touchdown did occur but due to the failure in the firing of its two harpoons, Philae bounced and travelled across the comet making contact with the surface twice more before finally landing in a shaded rocky location somewhere on the southern hemisphere of the comet. The search campaign, led by ESA, involved multiple teams across Europe with a wide range of techniques used in support of it. This search campaign would continue through 2015 where a prime candidate on the surface was identified and on into 2016 to end on the 2nd of September 2016 when a definitive and conclusive image was taken of the lander on the surface of the comet, confirming the prime candidate to indeed be Philae

AOCS operations preparation for the BepiColombo mission to mercury

The 2018 ESA/JAXA BepiColombo mission to Mercury features a complex modular design, with two scientific Mercury orbiters and a cruise module. The spacecraft (S/C) and mission design lead to a number of challenges for the attitude and orbit control system (AOCS), including electric propulsion usage during cruise to Mercury, AOCS capability to deal with several S/C configurations, and strict attitude constraints owing to the harsh thermal environment. This paper presents the activities for AOCS operations preparation by ESA/ESOC, covering the current preparation status as well as an outlook on upcoming activities before launch

Crystal structure of avian carboxypeptidase D domain II: a prototype for the regulatory metallocarboxypeptidase subfamily.

The crystal structure of domain II of duck carboxypeptidase D, a prohormone/propeptide processing enzyme integrated in a three repeat tandem in the natural system, has been solved, constituting a prototype for members of the regulatory metallocarboxypeptidase subfamily. It displays a 300 residue N-terminal alpha/beta-hydrolase subdomain with overall topological similarity to and general coincidence of the key catalytic residues with the archetypal pancreatic carboxypeptidase A. However, numerous significant insertions/deletions in segments forming the funnel-like access to the active site explain differences in specificity towards larger protein substrates or inhibitors. This alpha/beta-hydrolase subdomain is followed by a C-terminal 80 residue beta-sandwich subdomain, unique for these regulatory metalloenzymes and topologically related to transthyretin and sugar-binding proteins. The structure described here establishes the fundamentals for a better understanding of the mechanism ruling events such as prohormone processing and will enable modelling of regulatory carboxypeptidases as well as a more rational design of inhibitors of carboxypeptidase D

Branch and win: OR tree search algorithms for solving combinatorial optimisation problems

Combinatorial optimization, branch and bound, artificial intelligence, 90C27, 90C57, 68T20,

Mars Express: 20 Years of Mission, Science Operations and Data Archiving

International audienceLaunched on 2 June 2003 and arriving at Mars on 25 December 2003 after a 7-month inter-planetary cruise, Mars Express was the European Space Agency’s first mission to arrive atanother planet. After more than 20 years in orbit, the spacecraft and science payload remainin good health and the mission has become the second oldest operational planetary orbiterafter Mars Odyssey.This contribution summarizes the Mars Express mission operations, science planningand data archiving systems, processes, and teams that are necessary to run the mission, planthe scientific observations, and execute all necessary commands. It also describes the datadownload, the ground processing and distribution to the scientific community for the studyand analysis of Mars sub-surface, surface, atmosphere, magnetosphere, and moons.This manuscript also describes the main challenges throughout the history of the mission,including several potentially mission-ending anomalies. We summarize the evolution of theground segment to provide new capabilities not envisaged before launch, whilst simultane-ously maintaining or even increasing the quality and quantity of scientific data generate

Mars Express investigations of Phobos and Deimos

International audienceThe Mars Express mission was launched in June 2003 and was inserted into orbit around Mars in December 2003. Its main objective is to study the Mars' subsurface, surface, atmosphere and interaction with the solar wind. A secondary objective is to study the martian moons, in particular the largest one Phobos, thanks to a near polar and elliptical orbit which allows the spacecraft to perform close flybys about every five months. The Mars Express data not only consist of high-resolution 3D color images, but also astrometric images, spectra from 0.18 to 20 μm, radar echoes, Doppler signals from gravity experiments, and ion data. A new view of the moons has emerged from this data set, favoring now the idea that they are not captured asteroids, but rather the result of a re-accretion following a major impact on Mars. This unique set of data is available in the ESA Planetary Science Archive (PSA) and mirror imaged in the NASA Planetary Data System (PDS). This paper presents an overview of the Mars Express Phobos flybys, the specificities of their operations and the scientific achievements