225 research outputs found
Featural and configurational processes in the recognition of faces of different familiarity
Previous research suggests that face recognition may involve both configurational and piecemeal (featural) processing. To explore the relationship between these processing modes, we examined the patterns of recognition impairment produced by blurring, inversion, and scrambling, both singly and in various combinations. Two tasks were used: recognition of unfamiliar faces (seen once before) and recognition of highly familiar faces (celebrities). The results provide further support for a configurational - featural distinction. Recognition performance remained well above chance if faces were blurred, scrambled, inverted, or simultaneously inverted and scrambled: each of these manipulations disrupts either configurational or piecemeal processing, leaving the other mode available as a route to recognition. However, blurred/scrambled and blurred/inverted faces were recognised at or near chance levels, presumably because both configurational processing and featural processing were disrupted. Similar patterns of effects were found for both familiar and unfamiliar faces, suggesting that the relationship between configurational and featural processing is qualitatively similar in both cases
Pathways to suicide-related behavior in offspring of mothers with depression: the role of offspring psychopathology
Objective
Offspring of mothers with depression are a high-risk group for the development of suicide-related behavior. These offspring are therefore a priority for preventive interventions; however, pathways contributing to risk, including specific aspects of offspring psychopathology, remain unclear. The aim of this study was to examine whether offspring symptoms of major depressive disorder (MDD), generalized anxiety disorder (GAD), disruptive behavior disorder (DBD), attention-deficit/hyperactivity disorder (ADHD), and alcohol abuse independently mediate the association between maternal depression and offspring suicide-related behavior.
Method
Data were used from a population-based birth cohort, the Avon Longitudinal Study of Parents and Children (ALSPAC). Three distinct classes of depression symptoms across the mothers’ first 11 years of their child’s life were identified (minimal, moderate, chronic-severe). Offspring psychopathology was assessed at age 15 years and suicide-related behavior at age 16 years. Data were analyzed using structural equation modeling.
Results
There was evidence for increased risk of suicidal ideation in offspring of mothers with chronic-severe depression symptoms in comparison to offspring of mothers with minimal symptoms (odds ratio = 3.04, 95% CI = 2.19, 4.21). This association was independently mediated by offspring MDD, GAD, and DBD symptoms. The same mechanisms were found for offspring of mothers with moderate depression symptoms over time. Results were similar for offspring suicide attempt except for additional evidence of an indirect effect through offspring ADHD symptoms.
Conclusion
Findings highlight that suicide prevention efforts in offspring of mothers with depression should not only be targeted at offspring with MDD; it is also important to consider offspring with other forms of psychopathology
Explaining long-term trends in adolescent emotional problems: what we know from population-based studies
Over the past four decades, rates of emotional problems in adolescents have increased in many countries, and outcomes for those with mental health problems have worsened. In this review we explore existing population-based studies to evaluate possible explanations for these trends. We include population-based studies that examine both trends in adolescent emotional problems, as well as risk or protective factors previously hypothesised to be associated with trends in youth depression and anxiety. The available evidence on risk or protective factors trends related to family life, young people’s health behaviours and lifestyle, school environment, peer relationships, as well as poverty. Studies reviewed suggest that trends in emotional problems are associated with increases in parental emotional problems, youth weight-control behaviours and eating disorders, school-related stress, as well as a rise in family poverty and social inequality in the 21st Century. One of the biggest changes in young people’s lives over the last few decades has been the rise of digital media to access information and interact with others, but implications for trends in mental health remain unclear. Other trends are likely to have mitigated against even steeper increases in youth emotional problems, for example improvements in youth substance use and a possible long-term reduction in child maltreatment. Epidemiological studies of unselected cohorts testing explanations for secular trends in mental health are scarce and an urgent priority for future research. Such studies will need to prioritise collection of comparable data in repeated population cohorts. Improving young people’s mental health is a major societal challenge, but considerably more needs to be done to understand the connections between social change and trends in youth mental health
Predictors of suicidality across the life span: The Isle of Wight study
Background
Data from a representative community sample were used to explore predictors of lifetime suicidality and to examine associations between distal adolescent and more proximal adult risks.
Method
Data are from a midlife follow-up of the Isle of Wight study, an epidemiological sample of adolescents assessed in 1968. Ratings of psychiatric symptoms and disorder, relationships and family functioning and adversity were made in adolescence; adult assessments included lifetime psychiatric history and suicidality, neuroticism and retrospective reports of childhood sexual abuse and harsh parenting.
Results
A wide range of measures of childhood psychopathology, adverse experiences and interpersonal difficulties were associated with adult suicidality; associations were particularly strong for adolescent irritability, worry and depression. In multivariate analyses, substantial proportions of these effects could be explained by their association with adult psychopathology and neuroticism, but additional effects remained for adolescent irritability and worry.
Conclusions
Factors of importance for long-term suicidality risk are evident in adolescence. These include family and experiential adversities as well as psychopathology. In particular, markers of adolescent worry and irritability appeared both potent risks and ones with additional effects beyond associations with adult disorder and adult neuroticism
Variable emergence of Autism Spectrum Disorder symptoms from childhood to early adulthood
OBJECTIVE: Autism spectrum disorder (ASD) is currently considered an early-onset, neurodevelopmental condition. Follow-up studies of clinic-ascertained autism suggest that autistic symptoms typically decline with age, although symptom improvement is limited for some. To date there have been no population-based prospective studies investigating the natural history of autistic symptoms from childhood to adulthood. This study aimed to characterize the development and heterogeneity of autistic symptoms in a UK population-based cohort from childhood to age 25 years. METHOD: Data were analyzed in a prospective UK population-based cohort (ALSPAC). Trajectories were derived using five-assessments of parentrated Social Communication Disorders Checklist (SCDC) spanning ages 7-25 years. Additional measures were used to validate symptom trajectories. RESULTS: We identified three distinct SCDC trajectory classes: low (88.5%), declining (5.0%) and late‐emerging (6.5%). Both the declining and late-emerging classes were associated with child and adult ASD measures, low IQ, communication problems, peer problems and worse adult functioning, compared to the low class. Male sex was associated with an increased likelihood of being in the declining trajectory class (OR=2.84, 95% CI=2.19-3.69). This sex difference was not observed in the late-emerging group (OR=1.00, 95% CI=0.80-1.24) compared to the low class. CONCLUSIONS: ASD symptom levels emerged early and tended to decline across development although impairment was still present in adulthood for some. For others, autistic symptoms emerged across adolescence and adulthood. This challenges our current understanding that ASD symptoms inevitably first manifest early in development
Considerations in Selecting Venues for the American Thoracic Society International Conference: Balancing Competing Priorities of the Society\u27s Diverse Membership
Is there a linear or a nonlinear relationship between rotation and configural processing of faces?
Research suggests that inverted faces are harder to recognise than upright faces because of a disruption in processing their configural properties. Reasons for this difficulty were explored by investigating people's ability to identify faces at intermediate angles of rotation. Participants were asked to discriminate blurred famous and unfamiliar faces presented at nine angles. Blurred faces were used to minimise featural processing strategies, and to assess the effects of rotation that are specific to configural processing. The results indicate a linear relationship between angle of rotation and recognition accuracy. It appears that configural processing becomes gradually more disrupted the further a face is oriented away from the upright. The implications of these findings for competing explanations of the face-inversion effect are discussed
“Late-onset” ADHD symptoms in young adulthood:is this the same as child-onset ADHD?
Objective: We investigated whether “late-onset” ADHD that emerges in adolescence/adulthood is similar in risk factor profile to: (1) child-onset ADHD, but emerges later because of scaffolding/compensation from childhood resources; and (2) depression, because it typically onsets in adolescence/adulthood and shows symptom and genetic overlaps with ADHD. Methods: We examined associations between late-onset ADHD and ADHD risk factors, cognitive tasks, childhood resources and depression risk factors in a population-based cohort followed-up to age 25 years (N=4224–9764). Results: Parent-rated late-onset ADHD was like child-onset persistent ADHD in associations with ADHD polygenic risk scores and cognitive task performance, although self-rated late-onset ADHD was not. Late-onset ADHD was associated with higher levels of childhood resources than child-onset ADHD and did not show strong evidence of association with depression risk factors. Conclusions: Late-onset ADHD shares characteristics with child-onset ADHD when parent-rated, but differences for self-reports require investigation. Childhood resources may delay the onset of ADHD
Cross-cohort change in parent-reported emotional problem trajectories across childhood and adolescence in the UK
Background
Over the past three decades, the prevalence of adolescent emotional problems (ie, anxiety and depression) has risen. Although the onset and developmental course of emotional symptoms shows high variability, no study has directly tested secular differences across development. Our aim was to investigate whether and how developmental trajectories of emotional problems have changed across generations.
Methods
We used data from two UK prospective cohorts assessed 10 years apart: the Avon Longitudinal Study of Parents and Children (ALSPAC) including individuals born in 1991–92, and the Millennium Cohort Study (MCS) with individuals born in 2000–02. Our outcome was emotional problems, assessed using the parent-rated emotional subscale of the Strengths and Difficulties Questionnaire (SDQ-E) at approximate ages 4, 7, 8, 10, 11, 13, and 17 years in ALSPAC and ages 3, 5, 7, 11, 14, and 17 years in MCS. Participants were included if the SDQ-E was completed at least once in childhood and at least once in adolescence. Trajectories were generated using multilevel growth curve models using the repeated assessments of the SDQ-E in children aged 3–17 years.
Findings
Data were available for 19 418 participants (7012 from ALSPAC and 12 406 from the MCS), of whom 9678 (49·8%) were female and 9740 (50·2%) were male, and 17 572 (90·5%) had White mothers. Individuals born between 2000 and 2002 had higher emotional problem scores from around 9 years (intercept statistic β 1·75, 95% CI 1·71–1·79) than did individuals born in 1991–92 (1·55, 1·51–1·59). The later cohort had an earlier onset of problems than the earlier cohort, and sustained higher average trajectories from around 11 years, with female adolescents showing the steepest trajectories of emotional problems. Differences between cohorts peaked overall at age 14 years.
Interpretation
Our comparison of two cohorts of young people provides evidence that compared with a cohort assessed 10 years prior, emotional problems emerge earlier in development in the more recent cohort, and these are especially pronounced for females during mid-adolescence. Such findings have implications for public health planning and service provision
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