2 research outputs found
Π‘ΠΈΠ½ΡΠ΅Π· ΠΈ ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΠΈΠ·Π°ΡΠΈΡ Π½Π°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»ΠΎΠ² Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ ΠΈΠ· ΡΠ°ΠΉΠ½ΠΎΠ³ΠΎ Π³ΡΠΈΠ±Π° Π΄Π»Ρ ΡΠ°Π½Π΅Π²ΡΡ ΠΏΠΎΠ²ΡΠ·ΠΎΠΊ
In this study, bacterial cellulose nanocrystals and aldehyde functionalized bacterial cellulose nanocrystals were synthesized from kombucha tea. Bacterial cellulose derived from kombucha tea is a biopolymer synthesized by a symbiotic consortium of bacteria and yeast (SCOBY). The main goal of this work was the synthesis and chemical modification of cellulose nanocrystals from bacterial cellulose isolated from kombucha tea. The hydrolysis of bacterial cellulose using sulfuric acid resulted in bacterial cellulose nanocrystals. Aldehyde modified bacterial cellulose nanocrystals were synthesized using periodate oxidation in order to acquire new properties such as a non-toxic crosslinking agent with other biopolymers. The bacterial cellulose nanocrystals and dialdehyde bacterial cellulose nanocrystals were characterized by FT-IR spectroscopy, Xβray diffraction, thermal analysis and particle size distribution. The synthesized bacterial cellulose nanocrystals and the dialdehyde derivative are excellent materials that could be used as potent wound dressing materials and scaffolds for tissue engineering applicationsΠ ΡΡΠΎΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠΈ Π½Π°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»Ρ Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ ΠΈ Π½Π°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»Ρ
Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ, ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ Π°Π»ΡΠ΄Π΅Π³ΠΈΠ΄Π½ΡΠΌΠΈ Π³ΡΡΠΏΠΏΠ°ΠΌΠΈ, Π±ΡΠ»ΠΈ ΡΠΈΠ½ΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½Ρ
ΠΈΠ· ΡΠ°ΠΉΠ½ΠΎΠ³ΠΎ Π³ΡΠΈΠ±Π°. ΠΠ°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½Π°Ρ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Π°, ΠΏΠΎΠ»ΡΡΠ΅Π½Π½Π°Ρ ΠΈΠ· ΡΠ°ΠΉΠ½ΠΎΠ³ΠΎ Π³ΡΠΈΠ±Π°, ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»ΡΠ΅Ρ ΡΠΎΠ±ΠΎΠΉ
Π±ΠΈΠΎΠΏΠΎΠ»ΠΈΠΌΠ΅Ρ, ΡΠΈΠ½ΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½Π½ΡΠΉ ΡΠΈΠΌΠ±ΠΈΠΎΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΊΠΎΠ½ΡΠΎΡΡΠΈΡΠΌΠΎΠΌ Π±Π°ΠΊΡΠ΅ΡΠΈΠΉ ΠΈ Π΄ΡΠΎΠΆΠΆΠ΅ΠΉ (SCOBY).
ΠΡΠ½ΠΎΠ²Π½ΠΎΠΉ ΡΠ΅Π»ΡΡ Π΄Π°Π½Π½ΠΎΠΉ ΡΠ°Π±ΠΎΡΡ Π±ΡΠ» ΡΠΈΠ½ΡΠ΅Π· ΠΈ Ρ
ΠΈΠΌΠΈΡΠ΅ΡΠΊΠ°Ρ ΠΌΠΎΠ΄ΠΈΡΠΈΠΊΠ°ΡΠΈΡ Π½Π°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»ΠΎΠ²
ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ ΠΈΠ· Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ, Π²ΡΠ΄Π΅Π»Π΅Π½Π½ΠΎΠΉ ΠΈΠ· ΡΠ°ΠΉΠ½ΠΎΠ³ΠΎ Π³ΡΠΈΠ±Π°. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ Π³ΠΈΠ΄ΡΠΎΠ»ΠΈΠ·Π°
Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ ΡΠ΅ΡΠ½ΠΎΠΉ ΠΊΠΈΡΠ»ΠΎΡΠΎΠΉ Π±ΡΠ»ΠΈ ΠΏΠΎΠ»ΡΡΠ΅Π½Ρ Π½Π°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»Ρ Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ
ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ. ΠΠ°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»Ρ Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ, ΠΌΠΎΠ΄ΠΈΡΠΈΡΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ Π°Π»ΡΠ΄Π΅Π³ΠΈΠ΄Π½ΡΠΌΠΈ
Π³ΡΡΠΏΠΏΠ°ΠΌΠΈ, Π±ΡΠ»ΠΈ ΡΠΈΠ½ΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½Ρ Ρ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°Π½ΠΈΠ΅ΠΌ ΠΏΠ΅ΡΠΈΠΉΠΎΠ΄Π°ΡΠ° Π΄Π»Ρ ΠΏΡΠΈΠΎΠ±ΡΠ΅ΡΠ΅Π½ΠΈΡ Π½ΠΎΠ²ΡΡ
ΡΠ²ΠΎΠΉΡΡΠ²,
ΡΠ°ΠΊΠΈΡ
ΠΊΠ°ΠΊ Π½Π΅ΡΠΎΠΊΡΠΈΡΠ½ΡΠΉ ΡΡΠΈΠ²Π°ΡΡΠΈΠΉ Π°Π³Π΅Π½Ρ Ρ Π΄ΡΡΠ³ΠΈΠΌΠΈ Π±ΠΈΠΎΠΏΠΎΠ»ΠΈΠΌΠ΅ΡΠ°ΠΌΠΈ. ΠΠ°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»Ρ
Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ ΠΈ Π½Π°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»Ρ Π΄ΠΈΠ°Π»ΡΠ΄Π΅Π³ΠΈΠ΄Π½ΠΎΠΉ Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ Π±ΡΠ»ΠΈ
ΠΎΡ
Π°ΡΠ°ΠΊΡΠ΅ΡΠΈΠ·ΠΎΠ²Π°Π½Ρ Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΠ-Π€ΡΡΡΠ΅-ΡΠΏΠ΅ΠΊΡΡΠΎΡΠΊΠΎΠΏΠΈΠΈ,
ΡΠ΅Π½ΡΠ³Π΅Π½ΠΎΠ²ΡΠΊΠΎΠΉ Π΄ΠΈΡΡΠ°ΠΊΡΠΈΠΈ, ΡΠ΅ΡΠΌΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ
Π°Π½Π°Π»ΠΈΠ·Π°, ΠΈ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Ρ ΡΠ°ΡΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΡ ΡΠ°ΡΡΠΈΡ ΠΏΠΎ ΡΠ°Π·ΠΌΠ΅ΡΠ°ΠΌ. Π‘ΠΈΠ½ΡΠ΅Π·ΠΈΡΠΎΠ²Π°Π½Π½ΡΠ΅ Π½Π°Π½ΠΎΠΊΡΠΈΡΡΠ°Π»Π»Ρ
Π±Π°ΠΊΡΠ΅ΡΠΈΠ°Π»ΡΠ½ΠΎΠΉ ΡΠ΅Π»Π»ΡΠ»ΠΎΠ·Ρ ΠΈ Π΅Π΅ ΡΡΠ½ΠΊΡΠΈΠΎΠ½Π°Π»ΠΈΠ·ΠΈΡΠΎΠ²Π°Π½Π½ΠΎΠ΅ Π°Π»ΡΠ΄Π΅Π³ΠΈΠ΄Π½ΡΠΌΠΈ Π³ΡΡΠΏΠΏΠ°ΠΌΠΈ ΠΏΡΠΎΠΈΠ·Π²ΠΎΠ΄Π½ΠΎΠ΅
ΡΠ²Π»ΡΡΡΡΡ ΠΏΡΠ΅Π²ΠΎΡΡ
ΠΎΠ΄Π½ΡΠΌΠΈ ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»Π°ΠΌΠΈ, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΌΠΎΠΆΠ½ΠΎ ΠΈΡΠΏΠΎΠ»ΡΠ·ΠΎΠ²Π°ΡΡ Π² ΠΊΠ°ΡΠ΅ΡΡΠ²Π΅ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΡΡ
ΠΏΠ΅ΡΠ΅Π²ΡΠ·ΠΎΡΠ½ΡΡ
ΠΌΠ°ΡΠ΅ΡΠΈΠ°Π»ΠΎΠ² Π΄Π»Ρ ΡΠ°Π½ ΠΈ ΠΊΠ°ΡΠΊΠ°ΡΠΎΠ² Π΄Π»Ρ ΠΏΡΠΈΠ»ΠΎΠΆΠ΅Π½ΠΈΠΉ ΡΠΊΠ°Π½Π΅Π²ΠΎΠΉ ΠΈΠ½ΠΆΠ΅Π½Π΅ΡΠΈ
A Review on Chitosan and Cellulose Hydrogels for Wound Dressings
Wound management remains a challenging issue around the world, although a lot of wound dressing materials have been produced for the treatment of chronic and acute wounds. Wound healing is a highly dynamic and complex regulatory process that involves four principal integrated phases, including hemostasis, inflammation, proliferation, and remodeling. Chronic non-healing wounds are wounds that heal significantly more slowly, fail to progress to all the phases of the normal wound healing process, and are usually stalled at the inflammatory phase. These wounds cause a lot of challenges to patients, such as severe emotional and physical stress and generate a considerable financial burden on patients and the general public healthcare system. It has been reported that about 1β2% of the global population suffers from chronic non-healing wounds during their lifetime in developed nations. Traditional wound dressings are dry, and therefore cannot provide moist environment for wound healing and do not possess antibacterial properties. Wound dressings that are currently used consist of bandages, films, foams, patches and hydrogels. Currently, hydrogels are gaining much attention as a result of their water-holding capacity, providing a moist wound-healing milieu. Chitosan is a biopolymer that has gained a lot of attention recently in the pharmaceutical industry due to its unique chemical and antibacterial nature. However, with its poor mechanical properties, chitosan is incorporated with other biopolymers, such as the cellulose of desirable biocompatibility, at the same time having the improved mechanical and physical properties of the hydrogels. This review focuses on the study of biopolymers, such as cellulose and chitosan hydrogels, for wound treatment