The suppression of DNA repair induced by PARP-1 inhibitors rucaparib and olaparib in combination with the radiopharmaceutical 131I-MIBG in noradrenaline transporter-expressing xenograft tumors

No abstract available

Computation of topside ionograms from N/h/ profiles

Computation of topside ionograms from electron concentration profile

Vibronic interactions in the visible and near-infrared spectra of C60− anions

Electron-phonon coupling is an important factor in understanding many properties of the C60 fullerides. However, there has been little success in quantifying the strength of the vibronic coupling in C60 ions, with considerable disagreement between experimental and theoretical results. We will show that neglect of quadratic coupling in previous models for C60- ions results in a significant overestimate of the linear coupling constants. Including quadratic coupling allows a coherent interpretation to be made of earlier experimental and theoretical results which at first sight are incompatible

The Rayleigh-Brillouin Spectrum in Special Relativistic Hydrodynamics

In this paper we calculate the Rayleigh-Brillouin spectrum for a relativistic simple fluid according to three different versions available for a relativistic approach to non-equilibrium thermodynamics. An outcome of these calculations is that Eckart's version predicts that such spectrum does not exist. This provides an argument to question its validity. The remaining two results, which differ one from another, do provide a finite form for such spectrum. This raises the rather intriguing question as to which of the two theories is a better candidate to be taken as a possible version of relativistic non-equilibrium thermodynamics. The answer will clearly require deeper examination of this problem.Comment: 13 pages, no figures. Accepted for publication in Phys. Rev.

Gamma-ray emission from dark matter wakes of recoiled black holes

A new scenario for the emission of high-energy gamma-rays from dark matter annihilation around massive black holes is presented. A black hole can leave its parent halo, by means of gravitational radiation recoil, in a merger event or in the asymmetric collapse of its progenitor star. A recoiled black hole which moves on an almost-radial orbit outside the virial radius of its central halo, in the cold dark matter background, reaches its apapsis in a finite time. Near or at the apapsis passage, a high-density wake extending over a large radius of influence, forms around the black hole. It is shown that significant gamma-ray emission can result from the enhancement of neutralino annihilation in these wakes. At its apapsis passage, a black hole is shown to produce a flash of high-energy gamma-rays whose duration is determined by the mass of the black hole and the redshift at which it is ejected. The ensemble of such black holes in the Hubble volume is shown to produce a diffuse high-energy gamma-ray background whose magnitude is compared to the diffuse emission from dark matter haloes alone.Comment: version to appear in Astrophysical Journal letters (labels on Fig. 3 corrected

Derivation of the Zakharov equations

This paper continues the study of the validity of the Zakharov model describing Langmuir turbulence. We give an existence theorem for a class of singular quasilinear equations. This theorem is valid for well-prepared initial data. We apply this result to the Euler-Maxwell equations describing laser-plasma interactions, to obtain, in a high-frequency limit, an asymptotic estimate that describes solutions of the Euler-Maxwell equations in terms of WKB approximate solutions which leading terms are solutions of the Zakharov equations. Because of transparency properties of the Euler-Maxwell equations, this study is led in a supercritical (highly nonlinear) regime. In such a regime, resonances between plasma waves, electromagnetric waves and acoustic waves could create instabilities in small time. The key of this work is the control of these resonances. The proof involves the techniques of geometric optics of Joly, M\'etivier and Rauch, recent results of Lannes on norms of pseudodifferential operators, and a semiclassical, paradifferential calculus