What Is in Your Beet Juice? Nitrate and Nitrite Content of Beet Juice Products Marketed to Athletes

Consumption of beetroot juice (BRJ) supplements has become popular among athletes because beets tend to be rich in nitrate (NO3 − ), which can enhance exercise performance by increasing nitric oxide production. The NO3 − content of beets can vary significantly, however, making it difficult to know how much NO3 − any product actually contains. Samples from 45 different lots of 24 different BRJ products from 21 different companies were therefore analyzed for NO3 − (and nitrite [NO2 − ]) concentration using high-performance liquid chromatography. The NO3 − and NO2 − content (i.e., amount per serving) was then calculated based on either (a) the manufacturer’s recommended serving size (for prepackaged/single dose products) or (b) as used in previous studies, a volume of 500 ml (for BRJ sold in bulk containers). There was moderate-to-large variability in NO3 − content between samples of the same product, with a mean coefficient of variation of 30% ± 26% (range 2–83%). There was even greater variability between products, with a ∼50-fold range in NO3 − content between the lowest and highest. Only five products consistently provided ≥5 mmol of NO3 − /serving, which seems to be the minimal dose required to enhance exercise performance in most individuals. NO2 − contents were generally low (i.e., ≤0.5% compared with NO3 − ), although two products contained 10% and 14%. The results of this study may be useful to athletes and their support staff contemplating which (if any) BRJ product to utilize. These data may also offer insight into variability in the literature with respect to the effects of BRJ on exercise performance

Bringing Lunar LiDAR Back Down to Earth: Mapping Our Industrial Heritage through Deep Transfer Learning

This is the final version. Available on open access from MDPI via the DOI in this recordThis article presents a novel deep learning method for semi-automated detection of historic mining pits using aerial LiDAR data. The recent emergence of national scale remotely sensed datasets has created the potential to greatly increase the rate of analysis and recording of cultural heritage sites. However, the time and resources required to process these datasets in traditional desktop surveys presents a near insurmountable challenge. The use of artificial intelligence to carry out preliminary processing of vast areas could enable experts to prioritize their prospection focus; however, success so far has been hindered by the lack of large training datasets in this field. This study develops an innovative transfer learning approach, utilizing a deep convolutional neural network initially trained on Lunar LiDAR datasets and reapplied here in an archaeological context. Recall rates of 80% and 83% were obtained on the 0.5 m and 0.25 m resolution datasets respectively, with false positive rates maintained below 20%. These results are state of the art and demonstrate that this model is an efficient, effective tool for semi-automated object detection for this type of archaeological objects. Further tests indicated strong potential for detection of other types of archaeological objects when trained accordingly

The Use of Remote Sensing Techniques for Monitoring and Characterization of Slope Instability

This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Understanding changes in slope geometry and knowledge of underlying engineering properties of the rock mass are essential for the safe design of man-made slopes and to reduce the significant risks associated with slope failure. Recent advances in the geomatics industry have provided the capability to obtain accurate, fully geo-referenced three-dimensional datasets that can be subsequently interrogated to provide engineering-based solutions for monitoring of deformation processes, rock mass characterization and additional insight into any underlying failure mechanisms. Importantly, data can also be used to spatially locate and map geological features and provide displacement or deformation rate information relating to movement of critical sections or regions of a slope. This paper explores the benefits that can be obtained by incorporating different remote sensing techniques and conventional measurement devices to provide a comprehensive database required for development of an effective slope monitoring and risk management program. The integration of different techniques, such as high accuracy discrete point measurement at critical locations, which can be used to complement larger scale less dense three-dimensional survey will be explored. Case studies using a combination of aerial and terrestrial laser scanning, unmanned aerial vehicle and hand-held scanning devices will demonstrate their ability to provide spatial data for informing decision making processes and ensuring compliance with Regulations

A combined field/remote sensing approach for characterizing landslide risk in coastal areas

This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Understanding the key factors controlling slope failure mechanisms in coastal areas is the first and most important step for analyzing, reconstructing and predicting the scale, location and extent of future instability in rocky coastlines. Different failure mechanisms may be possible depending on the influence of the engineering properties of the rock mass (including the fracture network), the persistence and type of discontinuity and the relative aspect or orientation of the coastline. Using a section of the North Coast of Cornwall, UK, as an example we present a multi-disciplinary approach for characterizing landslide risk associated with coastal instabilities in a blocky rock mass. Remotely captured terrestrial and aerial LiDAR and photogrammetric data was interrogated using Geographic Information System (GIS) techniques to provide a framework for subsequent analysis, interpretation and validation. The remote sensing mapping data was used to define the rock mass discontinuity network of the area and to differentiate between major and minor geological structures controlling the evolution of the North Coast of Cornwall. Kinematic instability maps generated from aerial LiDAR data using GIS techniques and results from structural and engineering geological surveys are presented. With this method, it was possible to highlight the types of kinematic failure mechanism that may generate coastal landslides and highlight areas that are more susceptible to instability or increased risk of future instability. Multi-temporal aerial LiDAR data and orthophotos were also studied using GIS techniques to locate recent landslide failures, validate the results obtained from the kinematic instability maps through site observations and provide improved understanding of the factors controlling the coastal geomorphology. The approach adopted is not only useful for academic research, but also for local authorities and consultancy's when assessing the likely risks of coastal instability

Underground mining of aggregates. Main report

This report examines the economic feasibility of underground mining for crushed rock aggregates in the UK, but particularly in the London, South East and East of England regions (the South East area of England). These regions import substantial volumes of crushed rock, primarily from the East Midlands and South West regions, requiring relatively long transport distances to market for this bulk commodity. A key part of the research was to determine whether or not aggregate could be produced and delivered to a local market from an underground aggregates operation at a cost comparable with that for production and transport of the commodity from traditional surface quarries located further afield. In essence the investigation asked – could the reduced transport costs compensate for the higher production costs underground so that underground crushed rock aggregates producers can compete with the established Leicestershire and Somerset surface quarries exporting to the South East? Work Programme The research effort involved establishing and verifying cost models for aggregates production, stone processing (sizing and sorting), haulage of product to market, environmental impact mitigation, health and safety, decommissioning and restoration. Another major element of the work was the re-examination of the BGS exploratory borehole and geophysical databases to identify potential areas of crushed rock aggregates resource at depth in the South East area of England. Land use pressure is typically higher in this area of England than elsewhere so another major part of the research was the identification of potential concurrent uses of land around the surface facilities of underground aggregates mines. The value, development costs for specific developments and determination of yields expected, from these uses were estimated. These were also used to investigate potential economic benefits associated with after uses of remediated surface land above potential underground aggregates mines and also for the new underground space that would be created. Key technical issues such as subsidence within relatively heavily populated areas of the South East area of England were also addressed. Economic Results The discounted cost of aggregate delivered at a discount rate of 10% was the metric used to appraise the options. This is the price of aggregate that leads to a zero net present value of project cash flows realised over the aggregates project life. The results show that the discounted costs of aggregate delivered to a local South East area of England market from an underground mine producing 3.5 million tonnes per annum (MTPA) of crushed rock aggregates, are in the range of £13.03 per tonne to £13.93 per tonne for the top six prospect locations. These are greater than the corresponding cost for a “reference” quarry in Leicestershire producing 3.5 MTPA (£10.95 per tonne), but lower than a “reference” quarry in Leicestershire producing 1.25 MTPA (£16.48 per tonne). These figures indicate that underground crushed rock aggregate mines located within the South East area of England may be able to compete for a share in the overall market by replacing / displacing aggregate imported from the quarries in Leicestershire and Somerset producing around or less than 1.25 MTPA. The surprise in these figures is not really that the more remote surface quarry has a lower discounted cost of aggregate delivered, but that the values for the quarry and underground mine are so close. The capital intensity for the development of underground aggregates mines was found to be higher than that required for surface quarries of comparable scale, by a factor ranging from 1.33 to 1.65 and thus may represent a disincentive for aggregates operators. Carbon Emissions The total carbon emissions of the ‘reference’ 3.5 MTPA quarry in Leicestershire were estimated at 9.28 kg CO2/tonne aggregate delivered and this is to be compared with carbon emissions for the 150 metre deep underground mines serving the local market which were estimated at 9.31 kg CO2/tonne delivered for a Bletchley prospect using an adit to access the sub-surface and 14.25 kg CO2/tonne delivered for a prospect based on the Chitty bore hole using a shaft. Depth of the mine is a key factor in determination of the relative carbon emissions from each of the underground mining operations considered as electricity consumption for ventilation, pumping and winding is proportional to depth. Recommendations The current research generated seven principal recommendations which are discussed in detail in the concluding section of the report. These are: Appraise policy incentives for underground aggregates mining. Conduct an industry-wide consultation on findings from the current research. Obtain public and stakeholder opinion on new uses for underground space. Conduct research to reducing the energy intensity of mine services. Develop a deep level aggregates-specific drilling campaign. Investigate underground aggregates mines developed from existing surface quarries. Investigate underground aggregates as co-products of industrial minerals mining

In vivo creatine kinase reaction kinetics at rest and stress in type II diabetic rat heart

The effects of type II diabetes on cardiac creatine kinase (CK) enzyme activity and/or flux are unknown. We therefore measured steady‐state phosphocreatine (PCr) and adenosine triphosphate (ATP) content and forward CK reaction kinetic parameters in Zucker Diabetic Fatty (ZDF) rat hearts, a type II diabetes research model. At baseline the PCr to ATP ratio (PCr/ATP) was significantly lower in diabetic heart when compared with matched controls (1.71 ± 0.21 vs. 2.26 ± 0.24, P < 0.01). Furthermore, the forward CK reaction rate constant (k(f)) was higher in diabetic animals (0.52 ± 0.09 s(−1) vs. 0.35 ± 0.06 s(−1), P < 0.01) and CK flux calculated as a product of PCr concentration ([PCr]) and k(f) was similar between two groups (4.32 ± 1.05 μmol/g/s vs. 4.94 ± 1.23 μmol/g/s, P = 0.20). Dobutamine administration resulted in similar increases in heart rate (~38%) and k(f) (~0.12 s(−1)) in both groups. No significant change in PCr and ATP content was observed with dobutamine. In summary, our data showed reduced PCr/ATP in diabetic myocardium as an indicator of cardiac energy deficit. The forward CK reaction rate constant is elevated at baseline which might reflect a compensatory mechanics to support energy flux through the CK shuttle and maintain constant ATP supply. When hearts were stimulated similar increase in k(f) was observed in both groups thus it seems that CK shuttle does not limit ATP supply for the range of workload studied

The Integration of Laser Scanning and 3D Models in the Legal Process following an Industrial Accident

PublishedThis is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Background In order to obtain a deeper understanding of an incident, it needs to be investigated to "peel back the layers" and examine both the immediate and underlying failures that contributed to the event itself. One of the key elements of effective accident investigation is recording the scene for future reference. In recent years, however, there have been major advances in survey technology, which have provided the ability to capture scenes in 3D to an unprecedented level of detail, using laser scanners. Methods A case study involving a fatal incident was surveyed using 3D laser scanning and then subsequently recreated through virtual and physical models. The created models were then utilised in both the accident investigation and legal process top explore the technologies use in this setting. Results Benefits include; explanation of the event and environment, incident reconstruction, preservation of evidence, reducing the need for site visits, testing of theories. Drawbacks include; limited technology within court rooms, confusion caused by models, cost, personal interpretation and acceptance in the data. Conclusions The use of laser scanning surveys can be of considerable use in jury trials, for example, if the location supports the use of a high definition survey or if an object has be altered after the accident and has a specific influence on the case and needs to be recorded. However, consideration has to be made in its application and to ensure a fair trial, emphasis being placed on the facts of the case and personal interpretation controlled.The Authors would like to acknowledge the European Social Fund for providing funding for this research. In addition, the authors would also like to acknowledge 3DMSI Ltd for their assistance throughout this research

The Benefits of Laser Scanning & 3D Modelling in Accident Investigation: In a Mining Context

PublishedArticleThis is the author’s final accepted version of the article: M. L. Eyre, P. J. Foster, J. Jobling-Purser and J. Coggan. "The benefits of laser scanning and 3D modelling in accident investigation: in a mining context." Mining Technology 2015; 124(2), 73-77. DOI: 10.1179/1743286315Y.0000000004Accurate reconstruction of the facts and causes surrounding accidents is critical if the mining industry is to learn from incidents and prevent future events. Effective accident investigation and training are essential in order to accomplish this, while providing a record of the incident in order to help in explaining the situation to people unconnected to the event itself. Over a number of years there have been considerable innovations in survey instrumentation and software used to record data. However, the final deliverable data has remained the same, with surveyors tasked to represent a 3D environment using 2D deliverables. This paper explores the benefits that can be obtained using 3D data capture and representation with regard to accident investigation with discussion on accuracy, time, witness verification and reduction in human error

The Charging Structure for the Great Barrier Reef - A review of willingness to pay

The Great Barrier Reef Marine Park Authority (GBRMPA or the Reef Authority) is currently conducting a comprehensive review of the charging structure for the use of the Great Barrier Reef (GBR) Marine Park with a view to implement potential changes from 1 July 2023