Tawney and the third way

From the 1920s to the 1950s R. H. Tawney was the most influential socialist thinker in Britain. He articulated an ethical socialism at odds with powerful statist and mechanistic traditions in British socialist thinking. Tawney's work is thus an important antecedent to third way thinking. Tawney's religiously-based critique of the morality of capitalism was combined with a concern for detailed institutional reform, challenging simple dichotomies between public and private ownership. He began a debate about democratizing the enterprise and corporate governance though his efforts fell on stony ground. Conversely, Tawney's moralism informed a whole-hearted condemnation of market forces in tension with both his concern with institutional reform and modern third way thought. Unfortunately, he refused to engage seriously with emergent welfare economics which for many social democrats promised a more nuanced understanding of the limits of market forces. Tawney's legacy is a complex one, whose various elements form a vital part of the intellectual background to current third way thinking

Phase 1 Anglo-French report on the IMPRESS Health 2 (Interreg IVA Channel Programme) project 4282: understanding factors behind the late testing and diagnosis of HIV

This report outlines the combined Anglo-French findings and analysis of data from the phase 1 (research) phase of the Interreg IVA Channel Programme funded IMPRESS Health 2 project examining factors behind the late testing and diagnosis of HIV in Kent, Medway, and Picardy (France)

Transcritical flow of a stratified fluid over topography: analysis of the forced Gardner equation

Transcritical flow of a stratified fluid past a broad localised topographic obstacle is studied analytically in the framework of the forced extended Korteweg--de Vries (eKdV), or Gardner, equation. We consider both possible signs for the cubic nonlinear term in the Gardner equation corresponding to different fluid density stratification profiles. We identify the range of the input parameters: the oncoming flow speed (the Froude number) and the topographic amplitude, for which the obstacle supports a stationary localised hydraulic transition from the subcritical flow upstream to the supercritical flow downstream. Such a localised transcritical flow is resolved back into the equilibrium flow state away from the obstacle with the aid of unsteady coherent nonlinear wave structures propagating upstream and downstream. Along with the regular, cnoidal undular bores occurring in the analogous problem for the single-layer flow modeled by the forced KdV equation, the transcritical internal wave flows support a diverse family of upstream and downstream wave structures, including solibores, rarefaction waves, reversed and trigonometric undular bores, which we describe using the recent development of the nonlinear modulation theory for the (unforced) Gardner equation. The predictions of the developed analytic construction are confirmed by direct numerical simulations of the forced Gardner equation for a broad range of input parameters.Comment: 34 pages, 24 figure

Flysch deposition and preservation of coherent bedding in an accretionary complex: Detrital zircon ages from the Upper Cretaceous Valdez Group, Chugach terrane, Alaska

The Upper Cretaceous Valdez Group represents the flysch facies of the Mesozoic Chugach terrane accretionary complex in southern Alaska. The Valdez Group is dominated by litharenite sandstone and argillite deposited as coherent beds, unlike the older McHugh Complex mélange and massive sandstones. Detrital zircons from five sandstones sampled along an ~55 km transect through the Valdez Group were dated using U-Pb laser ablation-multicollector-inductively coupled plasma-mass spectrometry (LA-MC-ICP-MS). The youngest populations from the two oldest samples, located along strike from each other, were 82-81 Ma. Three samples across strike and outboard of the others are separated by ~50 km, but each has a youngest population dated at ca. 68 Ma. All of these samples have major grain population ages that suggest erosion from the Coast Mountains Batholith, consistent with petrography and grain modes suggesting an arc source. No apparent age gap exists between the youngest McHugh Complex samples and the oldest Valdez Group samples, suggesting continuous deposition despite the different depositional and tectonic style. We propose a model in which the onset of coherently bedded flysch marks the transition from deposition in the trench or trench slope to deposition on the oceanic plate beyond the trench after it was filled at ca. 84 Ma, i.e., the time of the youngest mélange sedimentation. Preservation of coherent bedding resulted as large coherent blocks of Valdez Group rocks were imbricated into the subduction complex during continued subduction in Paleogene time. © 2011 Geological Society of America

Understanding factors behind the late testing and diagnosis of HIV: Findings from phase 1 of the IMPRESS Health 2 (Interreg IVA Channel Programme) Project

Over 100,000 have HIV in the UK. However, while effective treatment exists, there is neither a cure nor a preventive vaccine, so 500+ people die from AIDS every year with many others dying undiagnosed. Health policy focuses on prevention and support, but it is necessary to increase the number of early diagnoses and reduce the rate of spread (Public Health England, 2014). Approximately 25% of HIV positive individuals do not know their status however, and almost half of all UK diagnoses occur late. It is vital therefore, to understand and address barriers to early testing and diagnoses to address this trend. Clinical data for 240 patients diagnosed with HIV in 3 trusts in Kent and Medway over 5 years were analysed in relation to clinical, social, demographic and psychosexual factors likely to affect knowledge of HIV and their decision to seek a test. Fifty-three semi-structured interviews were also conducted with patients and healthcare professionals to elicit experienced and perceptions about barriers to testing and ways to increase uptake. Patients were aged 19-81 (mean 40 years) and 67.5% were men. Women were more likely to be diagnosed late however (67.9% versus 56.8%), and late diagnosis was higher than the national average for both sexes (60.4%) with the highest rates in Medway (66.1%) and Maidstone and Tunbridge Wells (64.6%). Patients diagnosed late were 4 years older than those diagnosed early, and late diagnosis was higher in ethnic minority groups (70.2%) compared to white British (53.0%). Those born outside the UK were also generally diagnosed later (69.8%). The most frequent categories affected were heterosexuals (56.2%), men who have sex with men (36.6%) and intravenous drug users (2.0%). Patients diagnosed during an acute hospital admission were far more likely to be diagnosed late (89.1%) compared to other settings (49.6% - 57.1%). Qualitative data suggested that outmoded notions of HIV as a ‘gay’ disease still prevailed and heterosexuals did not generally consider themselves to be at risk. Healthcare professionals sometimes failed to acknowledge risks in ‘non-traditional’ groups and often overlooked HIV as a likely cause of symptoms until they were seriously unwell. Clearer public health messages should be targeted at the general population and there is a need to better educate healthcare professionals, especially GPs about the clinical indicators of HIV which also needs to be de-stigmatised

Simultaneous 3D measurement of the translation and rotation of finite size particles and the flow field in a fully developed turbulent water flow

We report a novel experimental technique that measures simultaneously in three dimensions the trajectories, the translation, and the rotation of finite size inertial particles together with the turbulent flow. The flow field is analyzed by tracking the temporal evolution of small fluorescent tracer particles. The inertial particles consist of a super-absorbent polymer that renders them index and density matched with water and thus invisible. The particles are marked by inserting at various locations tracer particles into the polymer. Translation and rotation, as well as the flow field around the particle are recovered dynamically from the analysis of the marker and tracer particle trajectories. We apply this technique to study the dynamics of inertial particles much larger in size (Rp/{\eta} \approx 100) than the Kolmogorov length scale {\eta} in a von K\'arm\'an swirling water flow (R{\lambda} \approx 400). We show, using the mixed (particle/fluid) Eulerian second order velocity structure function, that the interaction zone between the particle and the flow develops in a spherical shell of width 2Rp around the particle of radius Rp. This we interpret as an indication of a wake induced by the particle. This measurement technique has many additional advantages that will make it useful to address other problems such as particle collisions, dynamics of non-spherical solid objects, or even of wet granular matter.Comment: 18 pages, 7 figures, submitted to "Measurement Science and Technology" special issue on "Advances in 3D velocimetry

Three-Dimensional Adaptive Grid Computation with Conservative, Marker-Based Tracking for Interfacial Fluid Dynamics

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76614/1/AIAA-2006-1523-676.pd

A systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective

The number of publications in the field of nanogenotoxicology and the amount of genotoxicity data on nanomaterials (NMs) in several databases generated by European Union (EU) funded projects have increased during the last decade. In parallel, large research efforts have contributed to both our understanding of key physico-chemical (PC) parameters regarding NM characterization as well as the limitations of toxicological assays originally designed for soluble chemicals. Hence, it is becoming increasingly clear that not all of these data are reliable or relevant from the regulatory perspective. The aim of this systematic review is to investigate the extent of studies on genotoxicity of NMs that can be considered reliable and relevant by current standards and bring focus to what is needed for a study to be useful from the regulatory point of view. Due to the vast number of studies available, we chose to limit our search to two large groups, which have raised substantial interest in recent years: nanofibers (including nanotubes) and metal-containing nanoparticles. Focusing on peer-reviewed publications, we evaluated the completeness of PC characterization of the tested NMs, documentation of the model system, study design, and results according to the quality assessment approach developed in the EU FP-7 GUIDEnano project. Further, building on recently published recommendations for best practices in nanogenotoxicology research, we created a set of criteria that address assay-specific reliability and relevance for risk assessment purposes. Articles were then reviewed, the qualifying publications discussed, and the most common shortcomings in NM genotoxicity studies highlighted. Moreover, several EU projects under the FP7 and H2020 framework set the aim to collectively feed the information they produced into the eNanoMapper database. As a result, and over the years, the eNanoMapper database has been extended with data of various quality depending on the existing knowledge at the time of entry. These activities are highly relevant since negative results are often not published. Here, we have reviewed the NanoInformaTIX instance under the eNanoMapper database, which hosts data from nine EU initiatives. We evaluated the data quality and the feasibility of use of the data from a regulatory perspective for each experimental entry