The long-term prognostic significance of 6-minute walk test distance in patients with chronic heart failure

Background. The 6-minute walk test (6-MWT) is used to assess patients with chronic heart failure (CHF). The prognostic significance of the 6-MWT distance during long-term followup ( > 5 years) is unclear. Methods. 1,667 patients (median [inter-quartile range, IQR]) (age 72 [65-77] ; 75% males) with heart failure due to left ventricular systolic impairment undertook a 6-MWT as part of their baseline assessment and were followed up for 5 years. Results. At 5 years' followup, those patients who died (n = 959) were older at baseline and had a higher log NT pro-BNP than those who survived to 5 years (n = 708). 6-MWT distance was lower in those who died [163 (153) m versus 269 (160) m; P 360 m. 6-MWT distance was a predictor of all-cause mortality (HR 0.97; 95% CI 0.96-0.97; Chi-square = 184.1; P < 0.0001). Independent predictors of all-cause mortality were decreasing 6-MWT distance, increasing age, increasing NYHA classification, increasing log NT pro-BNP, decreasing diastolic blood pressure, decreasing sodium, and increasing urea. Conclusion. The 6-MWT is an important independent predictor of all-cause mortality following long-term followup in patients with CHF. © 2014 Lee Ingle et al

Evaluating Consumer Sensory and Composition Attributes of Arkansas-Grown Fresh-Market Blackberries

Blackberries are grown worldwide for commercial fresh markets. Three Arkansas-grown fresh-market blackberry genotypes (‘Natchez’, ‘Ouachita’, and A-2418) were evaluated for consumer sensory and compositional attributes at the University of Arkansas Food Science Department, Fayetteville. The compositional attributes of the blackberries were within an acceptable range for commercial markets (soluble solids=8.20-11.90%, pH=2.79-3.18, titratable acidity=1.09-1.32%). In terms of soluble solids to titratable acidity ratio, ‘Ouachita’ (10.92) had the highest ratio, followed by ‘Natchez’ (8.93) and A-2418 (6.25). A consumer sensory panel (n=80) evaluated fresh-market blackberry attributes using a 9-point hedonic scale for overall impression, overall flavor, sweetness, and sourness and a 5-point Just-about-Right (JAR) scale for sweetness and sourness. The participants also ranked the blackberries in order of overall liking from most to least liked. For overall impression, overall flavor, and sweetness, ‘Natchez’ scored higher than ‘Ouachita’ and A-2418, but the panelists did not detect differences in sourness. In terms of JAR for sweetness, 64% of consumers scored ‘Natchez’ JAR, followed by ‘Ouachita’ (39%) and A-2418 (34%). Whereas, 42% percent found A-2418 “Too Sour”, followed by ‘Ouachita (33%) and ‘Natchez’ (25%). In terms of ranking the blackberries, ‘Natchez’ was the most liked blackberry followed by ‘Ouachita’ and A-2418. When looking only at blackberries ranked first, 53% of consumers ranked ‘Natchez’ as their most liked berry, compared to A-2418 (26%) and ‘Ouachita’ (21%). The results from this research suggested that fresh-market blackberries with medium-level sweetness to sourness ratios were preferred though more consumers than expected preferred the blackberries with the more extreme ratios

Pion-Nucleus Scattering at Medium Energies with Densities from Chiral Effective Field Theories

Recently developed chiral effective field theory models provide excellent descriptions of the bulk characteristics of finite nuclei, but have not been tested with other observables. In this work, densities from both relativistic point-coupling models and mean-field meson models are used in the analysis of meson-nucleus scattering at medium energies. Elastic scattering observables for 790 MeV/$c$ $\pi^{\pm}$ on $^{208}$Pb are calculated in a relativistic impulse approximation, using the Kemmer-Duffin-Petiau formalism to calculate the $\pi^{\pm}$ nucleus optical potential.Comment: 9 page