Taking Action for Looked After Children in School: A Knowledge Exchange Programme

This book will become a teaching resource for all professionals concerned with the education of children in care, such as designated teachers and Virtual School colleagues

Can Yoga Help Make the World a Better Place? Perceptions from Adult Practitioners

Yoga, a vast subject with ancient South Asian roots, is currently enjoying global popularity based largely on its representation as an alternative health care system and/or leisure activity. These depictions often overshadow its potential as a medium to express spiritual development and social justice aims. Extensive studies look at connections between yoga and spirituality, but few delve into how sustained yoga practice might stimulate interest in and action for social change. This study seeks to contribute to ongoing scholarly efforts to fill that gap. It analyzes data collected from 107 survey respondents and 15 interviewees through a theoretical lens encompassing elements of cosmopolitanism thought, Western adult education models, and the panchakoshas (five sheaths) described in the Taittiriya Upaniṣhad. Findings reveal that practitioners experience yoga for self-development, to support ever-broadening conceptions of family, to engage in multiple communities, and to realize universal truths. To conclude the study, I offer a conceptual framework that represents yoga as a lived philosophy consistent with cosmopolitan ideals to balance disciplined self-development with engaged care for making the world a better place

Constitutive expression of Yes-associated protein (Yap) in adult skeletal muscle fibres induces muscle atrophy and myopathy

Peer reviewedPublisher PD

Alcohol Misusers' experiences of employment and the benefit system

This study was commissioned by the Department for Work and Pensions (DWP) to explore the experiences of adults with alcohol misuse problems in the UK in relation to employment, unemployment and benefit uptake. A separate report contains the findings of a study to estimate the number of people who are accessing DWP benefits and who have a problematic relationship with alcohol (Hay et al., 2010)

Mental Health Act, 2001 Toolkit

Toolkit on the Mental Health Act, 2001The School of Law, University College Cork, has developed a Mental Health Act, 2001 Toolkit in partnership with Mental Health Reform. When people with mental health difficulties are admitted to mental health units, either on a voluntary or involuntary basis, it is vital that user-friendly, accessible, information is available regarding human rights. Access to this information is essential for people with mental health difficulties, their family members, advocates, supporters and carers. The Mental Health Act, 2001 Toolkit will be published on Mental Health Reform's website and will include information on topics such as the following: What are the main human rights in Mental Health law? What is the Mental Health Act? Can I make an Advance Healthcare Directive? The Role and Rights of my Supporters / Family / Carers Approved Centres and What to Expect. My Rights as a' Voluntary Patient'. My Rights as an 'Involuntary Patient'. Mental Health Tribunals Explained. Complaints, Advocacy and Activism. The Toolkit will be a vital means of empowerment, enabling people to become educated about their rights, so that they can exercise and claim those rights. This aids fuller realisation of rights provided by the UN Convention on the Rights of Persons with Disabilities (CRPD), the Irish Constitution, and other human rights documents. The Toolkit was drafted in consultation with Mental Health Reform's member organisations, through a series of online and in-person consultation meetings. The meetings were attended by a wide variety of people, including people with lived experience of mental health difficulties, family members, staff and supporters of organisations. This project was funded by the Irish Research Council. The researcher was Darius Whelan and the Research Assistant was Claire Carroll. The co-ordinator from Mental Health Reform was Ber Grogan

Adaptive estimation of the transition density of a particular hidden Markov chain

We study the following model of hidden Markov chain: $Y_i=X_i+\epsilon_i$, $i=1,...,n+1$ with $(X_i)$ a real-valued positive recurrent and stationary Markov chain and $(\epsilon_i)_{1\leq i\leq n+1}$ a noise independent of the sequence $(X_i)$ having a known distribution. We present an adaptive estimator of the transition density based on the quotient of a deconvolution estimator of the density of $X_i$ and an estimator of the density of $(X_i,X_{i+1})$. These estimators are obtained by contrast minimization and model selection. We evaluate the $L2$ risk and its rate of convergence for ordinary smooth and supersmooth noise with regard to ordinary smooth and supersmooth chains. Some examples are also detailed

Towards a new social justice agenda: understanding political responses to crises

This In Focus Policy Briefing was written by Naomi Hossain of the institute of development Studies with inputs and advice from Kate Bishop, Robert Chambers, Kate Carroll, Rosalind Eyben, Richard Jolly, Claire Melamed and Rachel Sabates-Wheeler. The series editor is Carol Smithyes.Food riots across the developing world in 2008 sent powerful messages about the limits to people’s tolerance of acute economic insecurity. Yet political responses of this kind are mainly treated as the inevitable social convulsions after economic shocks – as natural, almost physiological responses to hunger. This briefing proposes that these political responses to crises can provide insights into popular perspectives on the global political issues of the day: global economic uncertainty, the moral limits to market freedom, and responsibilities of governments to protect against risk. Understanding such perspectives could inform emerging debates within development and help shape a new social justice agenda

A pan-cetacean MHC amplicon sequencing panel developed and evaluated in combination with genome assemblies

This study was funded by a Royal Society Research Grants for Research Fellows (RGF\R1\181014) to E.C.G. E.C.G. is funded by a Royal Society University Research Fellowship (UF160081 & URF\R\221020). F.E. is supported by a University of St Andrews School of Biology Ph.D. scholarship and a Royal Society Research Fellows Enhancement Award (RGF\EA\180213 to E.C.G). E.L.C. is funded by a Rutherford Discovery Fellowship from the Royal Society of New Zealand Te Apārangi.The major histocompatibility complex (MHC) is a highly polymorphic gene family that is crucial in immunity, and its diversity can be effectively used as a fitness marker for populations. Despite this, MHC remains poorly characterised in non-model species (e.g., cetaceans: whales, dolphins and porpoises) as high gene copy number variation, especially in the fast-evolving class I region, makes analyses of genomic sequences difficult. To date, only small sections of class I and IIa genes have been used to assess functional diversity in cetacean populations. Here, we undertook a systematic characterisation of the MHC class I and IIa regions in available cetacean genomes. We extracted full-length gene sequences to design pan-cetacean primers that amplified the complete exon2 from MHC class I and IIa genes in one combined sequencing panel. We validated this panel in 19 cetacean species and described 354 alleles for both classes. Furthermore, we identified likely assembly artefacts for many MHC class I assemblies based on the presence of class I genes in the amplicon data compared to missing genes from genomes. Finally, we investigated MHC diversity using the panel in 25 humpback and 30 southern right whales, including four paternity trios for humpback whales. This revealed copy-number variable class I haplotypes in humpback whales, which is likely a common phenomenon across cetaceans. These MHC alleles will form the basis for a cetacean branch of the Immuno-Polymorphism Database (IPD-MHC), a curated resource intended to aid in the systematic compilation of MHC alleles across several species, to support conservation initiatives.Peer reviewe

Intonational variation in the North-West of England:The origins of a rising contour in Liverpool

This paper investigates intonation in the urban dialect of Liverpool, Scouse. Scouse is reported to be part of a group of dialects in the north of the UK where rising contours in declaratives are a traditional aspect of the dialect. This intonation is typologically unusual and has not been the subject of detailed previous research. Here, we present such an analysis in comparison to Manchester, a city less than 40 miles from Liverpool but with a noticeably different prosody. Our analysis confirms reports that rising contours are the most common realisation in Liverpool, specifically a low rise where final high pitch is not reached until the end of the phrase. Secondly, we consider the origin of declarative rises in Scouse with reference to the literature on new dialect formation. Our demographic analysis and review of previous work on relevant dialects suggests that declarative rises were not the majority variant when Scouse was formed but may have been adopted for facilitating communication in a diverse new community. We highlight this contribution of intonational data to research on phonological aspects of new dialect formation, which have largely considered segmental phonology or timing previously