Considerações iniciais sobre um ambiente rizomático de aprendizagem

This study proposes the creation of a learning network, structured in accordance with the assumptions of open education aiming to promote learning, exchange and collaboration among teachers participating in an in-service training. The development, structured following the rhizome shape, will allow participants to have freedom and autonomy to transform their space as they share their practices and transform themselves. Assessment will be done throughout the process, allowing all those who participate in learning communities, making use of the work with projects, to have the possibility of receiving a certificate of completion. The proposal aims at each participant to reflect, construct and deconstruct inclusive education practices in order to understand in a meaningful way what works in their own contexts, for their students and reality. This opens up the possibility for learning communities to be created where it is understood that learning is fluid, without beginning or end, in an incessant becoming. O presente estudo propõe a criação de uma rede de aprendizagem estruturada em conformidade com os pressupostos da educação aberta, visando promover a aprendizagem, a troca e a colaboração entre professores participantes de uma formação em serviço. A formação, estruturada em formato de rizoma, permitirá que os participantes tenham liberdade e autonomia para transformar o próprio espaço na medida em que compartilham suas práticas e transformam a si mesmos. A avaliação será feita processualmente ao longo de todo o processo, possibilitando que todos os que participarem das comunidades de aprendizagem, fazendo uso do trabalho com projetos, tenham a possibilidade de receber um certificado de conclusão. A proposta visa que cada participante reflita, construa e descontrua práticas de educação inclusiva a fim de compreender de forma significativa o que funciona no seu contexto, para os seus alunos e sua realidade. Abre-se assim a possibilidade para que sejam criadas comunidades de aprendizagem onde se compreende que a aprendizagem é fluida, sem começo e final, em um incessante devir

Availability and Use of Antibiotics in the Dormaa Municipal District of the Bono Region in Ghana. Report for Fleming Fund Fellowship Programme

The rise observed in antimicrobial resistance over the past decades has been linked to the dramatic increase in use of antibiotics in humans and animals. Few studies have prospectively examined the availability and use of antibiotics in humans and animals at the residential level in Ghana. This study was conducted to gather data on the availability and use of antibiotics among residents in a suburban municipality in Ghana. Data from such studies may aid policy makers to devise strategies to help consumers to minimise inappropriate use of antibiotics at the community level. This study is a cross-sectional study during which the study team assessed the availability and use of antibiotics in humans at the community level in the Dormaa municipality of the Bono Region in Ghana. Structured questionnaires and the Drug Bag’ method were employed to quantify antibiotic types available at the community level, frequently used antibiotics in the community as well as the disease conditions these antibiotics are used to treat. A total of 100 households, 6 retail community pharmacy outlets and 11 out-patient health facilities were visited. Questionnaires were administered to participants in the pharmacies and out-patient facilities whilst the ‘Drug Bag’ method was combined with questionnaires to gather data in the households. The study results revealed that the top four antibiotics used by respondents in the households in the communities surveyed often without prescription were Amoxicillin Capsules, Metronidazole Tablets, Phenoxymethylpenicillin Tablets and Tetracycline Capsules. These antibiotics are normally obtained from Over-the-Counter Medicines Sellers facilities and peddlers although such outlets are not permitted by law to stock and dispense these antibiotics. The top three disease conditions given by respondents in the study communities for which antibiotics are used are gastrointestinal diseases, followed by fever with body pains and cough and cold conditions. Antibiotics known and used by respondents in the community was compared with the WHO AWaRe classification tool. The study revealed that 50% and 47% respectively of antibiotics known and used by respondents fell within the “Access” list while 11% and 8% respectively of antibiotics known and used by respondents fell within the “Watch” list. None of the antibiotics in the “Reserve” list was known to or had been used by respondents. The research found that 85% of households had used antibiotics three months prior to the study in the vicinity. The study has revealed common antibiotic use among residents in the Dormaa municipality, including for diseases which are preventable. This paper therefore suggests that preventive approaches including improving access to water and sanitation facilities may improve infection prevention and control, leading to decreased incidence of infections such as gastrointestinal disturbances and a decrease in the perceived need for frequent antibiotic use. Awareness creation is also key in sensitising communities about the dangers of excessive use of antibiotics, including the emergence of AMR

Understanding antibiotic use: practices, structures and networks.

In this article, we consider how social sciences can help us to understand the rising use of antibiotics globally. Drawing on ethnography as a way to research how we are in the world, we explore scholarship that situates antibiotic use in relation to interactions of pathogens, humans, animals and the environment in the context of globalization, changes in agriculture and urbanization. We group this research into three areas: practices, structures and networks. Much of the public health and related social research concerning antimicrobial resistance has focused on antibiotic use as a practice, with research characterizing how antibiotics are used by patients, farmers, fishermen, drug sellers, clinicians and others. Researchers have also positioned antibiotic use as emergent of political-economic structures, shedding light on how working and living conditions, quality of care, hygiene and sanitation foster reliance on antibiotics. A growing body of research sees antibiotics as embedded in networks that, in addition to social and institutional networks, comprise physical, technical and historical connections such as guidelines, supply chains and reporting systems. Taken together, this research emphasizes the multiple ways that antibiotics have become built into daily life. Wider issues, which may be invisible without explication through ethnographic approaches, need to be considered when addressing antibiotic use. Adopting the complementary vantage points of practices, networks and structures can support the diversification of our responses to AMR

Antibiotic Use Among Poultry Farmers in the Dormaa Municipality, Ghana. Report for Fleming Fund Fellowship Programme

Introduction: Antibiotic use has contributed significantly to many successes in human medicine and improvement in animal welfare. There is however global concern about non-regulation of antibiotics in food producing animals due to the great threat it poses to public health. Local evidence is required to support the regulation of antibiotics in the thriving poultry sub-sector but such data are limited. The study was conducted to investigate antibiotic use among poultry farmers in the Dormaa Municipality of the Bono Region of Ghana. Method: A cross-sectional study was conducted in February to March 2020. A total of 161 commercial and backyard poultry farmers were interviewed using a “Drug bag” containing antibiotics purchased from the study area in addition to questionnaires to elicit responses about medicines. Treatment log books were also inspected where available. Results: Farms were classified as backyard (n=41) or small, medium or large scale commercial (n=120). Of the commercial farms, most respondents were farm managers or farm owners and most (91%) kept layer hens. All commercial farms reported using antibiotics, obtained mainly from the Agro-Vet shops without prescription, and for both therapeutic and non-therapeutic use, while 24% of backyard farmers also used antibiotics, obtained from human drug stores, primarily for therapeutic use. Over 60% of commercial farmers indicated the use of any of the four major classes of antibiotics, namely Aminoglycosides, Polymyxins, Macrolides and Tetracyclines which are critically important in human medicine. Backyard farmers mainly used penicillins. A majority (67%) of the commercial farmers reported self-administration of antibiotics based on the information they acquire from varied sources such as colleagues, drug and feed manufacturer representatives for therapeutic and non-therapeutic purposes on their farms with little or no supervision from the Veterinarian. Adherence to the withdrawal periods is very low due to financial implications of losing out on sales of batches of eggs, however, a few farmers did report complying to the withdrawal periods. Conclusion: Key concerns for antibiotic use in poultry in the Dormaa region are frequent use of critically important antibiotics without supervision from a competent official, easy access to antibiotics without prescription and non-adherence to withdrawal periods of medicines. To address this problem, whilst recognising the need for productivity of the poultry industry, the following actions are recommended to be piloted and evaluated: (1) Enhancement of the capacities of Veterinarians and Para veterinarians (Veterinary Technicians) to guide and offer adequate supervision in the administration of antibiotics on farms; (2) Regular farm-based trainings to create awareness on the importance of improving farm hygiene for minimizing antibiotic use, and in effective, affordable and feasible biosecurity and animal husbandry to achieve this; (3) Promotion of biologicals (vaccines, pre and probiotics) as an alternative to antimicrobial use in husbandry to reduce the development of resistance and accumulation of residues; (4) Development and enforcement of regulatory and advertising guidelines and prohibitions in the manufacture, import, sale and use of antibiotics at all levels through antibiotic stewardship strategies that engage and coordinate all relevant actors in the animal sector; (5) Enhanced monitoring – through improved capacity of the Veterinary Services Directorate – of levels of antibiotic residues and certification of animal products (e.g. poultry, fish) prior to their release into the markets to protect public health, environment and ensure sustainable productivity in the industry; (6) Sanctions, such as fines for defaulting farms, to serve as a deterrent to other potential and existing farms. Operational research, which takes an evidence based approach to track the effectiveness of such strategies, is required in order to informs ongoing investment in policies and services that can reduce recourse to antibiotics as the poultry industry undergoes its rapid expansion in Ghana

GAMES E EDUCAÇÃO: CONSIDERAÇÕES SOBRE ASSASSIN’S CREED E O ENSINO DE HISTÓRIA

Diante da constatação das mudanças significativas que são introduzidas na sociedade contemporânea através dos avanços tecnológicos e, dentro deste contexto, a ocorrência de novas relações no processo e ensino e aprendizagem, o objetivo deste texto foi refletir sobre as possibilidades que o game de temática histórica Assassin’s Creed tem oferecido para a prática docente em sala de aula. O estudo de caráter qualitativo foi pautado em uma revisão bibliográfica na qual foram investigadas questões como: O surgimento e as características do nativo digital e, em que medida suas experiências com a tecnologia estão sendo consideradas no planejamento do ensino; A pertinência da utilização dos games no ambiente escolar e o abismo que a escola tradicional mostra ao não valorizar um recurso que faz parte do cotidiano de seu novo aluno, recurso que possui um ótimo potencial para desenvolvimento cognitivo ao se considerar o ambiente de performance em que ficam submetidos os gamers/alunos durante sua prática. Por fim o texto busca mostrar as potencialidades da franquia Assassin’s Creed para o fazer pedagógico ao discorrer sobre um projeto de ensino desenvolvido em contexto educacional brasileiro e que obteve sucesso ao utilizar este jogo como recurso didático

Predictors of Antibiotics Co-prescription with Antimalarials for Patients Presenting with Fever in Rural Tanzania.

Successful implementation of malaria treatment policy depends on the prescription practices for patients with malaria. This paper describes prescription patterns and assesses factors associated with co-prescription of antibiotics and artemether-lumefantrine (AL) for patients presenting with fever in rural Tanzania. From June 2009 to September 2011, a cohort event monitoring program was conducted among all patients treated at 8 selected health facilities in Ifakara and Rufiji Health and Demographic Surveillance System (HDSS).It included all patients presenting with fever and prescribed with AL. Logistic regression was used to model the predictors on the outcome variable which is co-prescription of AL and antibiotics on a single clinical visit. A cohort of 11,648 was recruited and followed up with 92% presenting with fever. Presumptive treatment was used in 56% of patients treated with AL. On average 2.4 (1 -- 7) drugs was prescribed per encounter, indicating co-prescription of AL with other drugs. Children under five had higher odds of AL and antibiotics co-prescription (OR = 0.63, 95% CI: 0.46 -- 0.85) than those aged more than five years. Patients testing negative had higher odds (OR = 2.22, 95%CI: 1.65 -- 2.97) of AL and antibiotics co-prescription. Patients receiving treatment from dispensaries had higher odds (OR = 1.45, 95% CI: 0.84 -- 2.30) of AL and antibiotics co-prescription than those from served in health centres even though the deference was not statistically significant. Regardless the fact that Malaria is declining but due to lack of laboratories and mRDT in most health facilities in the rural areas, clinicians are still treating malaria presumptively. This leads them to prescribe more drugs to treat all possibilities

WASH and biosecurity interventions for reducing burdens of infection, antibiotic use and antimicrobial resistance in animal agricultural settings: a One Health mixed methods systematic review

Background: Infection prevention and control (IPC) is recognised as essential to addressing the emergence and spread of antimicrobial resistance (AMR) in human health, food production and the environment. How best to address this through a One Health perspective remains a challenge. This systematic review addresses this gap by identifying and synthesising evidence from interventions designed to improve water, hygiene, sanitation (WASH), and biosecurity in animal agriculture and in people that live and/or work with animals. This review aimed to capture evidence of effects of all types of intervention and across different settings. Methods: We conducted a systematic search for studies that reported on WASH and biosecurity interventions with the potential to reduce the burden of infections and reliance on antibiotics in animal production for populations living with animals and/or involved in agriculture/aquaculture with a primary focus on LMICs. We searched the following databases: Web of Science, PubMed, OVID, ProQuest, Epistemonikos, Trip, AgEcon, and Cochrane Library. For articles in Spanish, we searched Scielo, BIREME, E-Revistas, Redalyc, Lilacs, AfricaPortal, IMSEAR and WPRIM. A hand search of literature was also conducted in relevant sources, and Google Scholar and Open Grey were used for grey literature. The main outcomes of interest were: (i) reduction of infections/cases, (ii) reduction of bacterial load, and (iii) reduction of antimicrobial use and AMR. We extracted data from selected studies, performed a narrative synthesis, and developed a framework. PROSPERO Registration: The protocol for the systematic review was registered at PROSPERO, registration number CRD42020162345. Findings: A total of 104 studies were included in this systematic review. The majority of studies (64/104) (61.5%) were conducted in HICs, especially in Europe and the USA. Only 13 (12.5%) studies took place in LMICs. The majority of studies (77) were animal based, followed by 12 targeting both animals and the environment, nine focused exclusively on the environment, and only one study was exclusively about humans. Most studies were conducted in poultry (36) and pigs (27), and assessed impacts on multiple types of bacteria (commonly Salmonella spp. and Campylobacter spp.). Eighty-seven (87) studies assessed impact on IPC, 3 on AMU, and 14 on AMR. The interventions were classified as follows: 57 applied biological or chemical products to eliminate pathogens; 26 modified infrastructure and apparatus; 15 were educational/behavioural and one was a structural intervention. Around 52.8% (55/104) studies included WASH interventions focused on water quality (20), water quantity (2), hygiene (30), and sanitation (3). Likewise, 47.1% (49/104) included biosecurity interventions focused on bio-management (34), bio-containment (10), and bio-exclusion (5). Positive impacts were reported for 64 (61.5%) interventions, on infection burden (54/87), antibiotic use (3/3) or AMR (7/14). The majority were non-randomised studies (55), although a quarter were randomised controlled trials (26). A total of 27 studies were classified as having low risk of bias, 21 moderate and 56 high risk of bias. Interpretation: This review identifies a number of effective interventions to reduce the burden of infections, antimicrobial resistance and antibiotic use in animal agricultural settings. Interventions which undertook bio-management and bio-containment measures appeared to have positive effects most often. These measures attempted to create and maintain a conducive environment for animal raising in terms of physical infrastructure and protocols. The few studies reporting sanitation measures - which were similar to bio-containment interventions - all reported positive effects. By contrast, efforts to impact water quantity, water quality, and hygiene had more mixed effects on the outcomes assessed. Bio-exclusion interventions had mostly negative effects. Risk of bias was high or moderate in many studies, however, and publication bias should also be considered. The paucity of studies evaluating structural interventions needs to be addressed. There are opportunities to learn from biosecurity Interventions for WASH and we propose the 'A' In WASH represents both 'Animals' and 'Air' in recognition of pathways of infection that can be addressed to also impact AMR

Increased use of malaria rapid diagnostic tests improves targeting of anti-malarial treatment in rural Tanzania: implications for nationwide rollout of malaria rapid diagnostic tests.

ABSTRACT: BACKGROUND: The World Health Organization recommends parasitological confirmation of all malaria cases. Tanzania is implementing a phased rollout of malaria rapid diagnostic tests (RDTs) for routine use in all levels of care as one strategy to increase parasitological confirmation of malaria diagnosis. This study was carried out to evaluated artemisinin combination therapy (ACT) prescribing patterns in febrile patients with and without uncomplicated malaria in one pre-RDT implementation and one post-RDT implementation area. METHODS: A cross-sectional health facility surveys was conducted during high and low malaria transmission seasons in 2010 in both areas. Clinical information and a reference blood film on all patients presenting for an initial illness consultation were collected. Malaria was defined as a history of fever in the past 48 hours and microscopically confirmed parasitaemia. Routine diagnostic testing was defined as RDT or microscopy ordered by the health worker and performed at the health facility as part of the health worker-patient consultation. Correct diagnostic testing was defined as febrile patient tested with RDT or microscopy. Over-testing was defined as a febrile patient tested with RDT or microscopy. Correct treatment was defined as patient with malaria prescribed ACT. Over-treatment was defined as patient without malaria prescribed ACT. RESULTS: A total of 1,247 febrile patients (627 from pre-implementation area and 620 from post-implementation area) were included in the analysis. In the post-RDT implementation area, 80.9% (95% CI, 68.2-89.3) of patients with malaria received recommended treatment with ACT compared to 70.3% (95% CI, 54.7-82.2) of patients in the pre-RDT implementation area. Correct treatment was significantly higher in the post-implementation area during high transmission season (85.9% (95%CI, 72.0-93.6) compared to 58.3% (95%CI, 39.4-75.1) in pre-implementation area (p=0.01). Over-treatment with ACT of patients without malaria was less common in the post-RDT implementation area (20.9%; 95% CI, 14.7-28.8) compared to the pre-RDT implementation area (45.8%; 95% CI, 37.2-54.6) (p<0.01) in high transmission. The odds of overtreatment was significantly lower in post- RDT area (adjusted Odds Ratio (OR: 95%CI) 0.57(0.36-0.89); and much higher with clinical diagnosis adjusted OR (95%CI) 2.24(1.37-3.67) CONCLUSION: Implementation of RDTs increased use of RDTs for parasitological confirmation and reduced over-treatment with ACT during high malaria transmission season in one area in Tanzania. Continued monitoring of the national RDT rollout will be needed to assess whether these changes in case management practices will be replicated in other areas and sustained over time. Additional measures (such as refresher trainings, closer supervisions, etc) may be needed to improve ACT targeting during low transmission seasons