The Relational Blockworld Interpretation of Non-relativistic Quantum Mechanics

We introduce a new interpretation of non-relativistic quantum mechanics (QM) called Relational Blockworld (RBW). We motivate the interpretation by outlining two results due to Kaiser, Bohr, Ulfeck, Mottelson, and Anandan, independently. First, the canonical commutation relations for position and momentum can be obtained from boost and translation operators,respectively, in a spacetime where the relativity of simultaneity holds. Second, the QM density operator can be obtained from the spacetime symmetry group of the experimental configuration exclusively. We show how QM, obtained from relativistic quantum field theory per RBW, explains the twin-slit experiment and conclude by resolving the standard conceptual problems of QM, i.e., the measurement problem, entanglement and non-locality

Reconciling Spacetime and the Quantum: Relational Blockworld and the Quantum Liar Paradox

The Relational Blockworld (RBW) interpretation of non-relativistic quantum mechanics (NRQM) is introduced. Accordingly, the spacetime of NRQM is a relational, non-separable blockworld whereby spatial distance is only defined between interacting trans-temporal objects. RBW is shown to provide a novel statistical interpretation of the wavefunction that deflates the measurement problem, as well as a geometric account of quantum entanglement and non-separability that satisfies locality per special relativity and is free of interpretative mystery. We present RBW's acausal and adynamical resolution of the so-called "quantum liar paradox," an experimental set-up alleged to be problematic for a spacetime conception of reality, and conclude by speculating on RBW's implications for quantum gravity.Comment: As accepted for publication in Foundations of Physic

The Relational Blockworld Interpretation of Non-relativistic Quantum Mechanics

We introduce a new interpretation of non-relativistic quantum mechanics (QM) called Relational Blockworld (RBW). We motivate the interpretation by outlining two results due to Kaiser, Bohr, Ulfeck, Mottelson, and Anandan, independently. First, the canonical commutation relations for position and momentum can be obtained from boost and translation operators,respectively, in a spacetime where the relativity of simultaneity holds. Second, the QM density operator can be obtained from the spacetime symmetry group of the experimental configuration exclusively. We show how QM, obtained from relativistic quantum field theory per RBW, explains the twin-slit experiment and conclude by resolving the standard conceptual problems of QM, i.e., the measurement problem, entanglement and non-locality

Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.

Intracellular pathways leading from membrane receptor engagement to apoptotic cell death are still poorly characterized. We investigated the intracellular signaling generated after cross-linking of CD95 (Fas/Apo-1 antigen), a broadly expressed cell surface receptor whose engagement results in triggering of cellular apoptotic programs. DX2, a new functional anti-CD95 monoclonal antibody was produced by immunizing mice with human CD95-transfected L cells. Crosslinking of CD95 with DX2 resulted in the activation of a sphingomyelinase (SMase) in promyelocytic U937 cells, as well as in other human tumor cell lines and in CD95-transfected murine cells, as demonstrated by induction of in vivo sphingomyelin (SM) hydrolysis and generation of ceramide. Direct in vitro measurement of enzymatic activity within CD95-stimulated U937 cell extracts, using labeled SM vesicles as substrates, showed strong SMase activity, which required pH 5.0 for optimal substrate hydrolysis. Finally, all CD95-sensitive cell lines tested could be induced to undergo apoptosis after exposure to cell-permeant C2-ceramide. These data indicate that CD95 cross-linking induces SM breakdown and ceramide production through an acidic SMase, thus providing the first information regarding early signal generation from CD95, and may be relevant in defining the biochemical nature of intracellular messengers leading to apoptotic cell death

Deflating Quantum Mysteries via the Relational Blockworld

We present a spacetime setting for non-relativistic quantum mechanics that deflates "quantum mysteries" and relates non-relativistic quantum mechanics to special relativity. This is achieved by assuming spacetime symmetries are fundamental in a blockworld setting, i.e., by interpreting spacetime relations as fundamental to relata. To justify this Relational Blockworld (RBW), we adopt a result due to G. Kaiser whereby the relativity of simultaneity, stemming from the Poincare algebra of special relativity, is responsible for the canonical commutation relations of non-relativistic quantum mechanics. And, we incorporate a result due to A. Bohr, B. Mottelson and O. Ulfbeck whereby the density matrix for a given experimental situation is obtained from its spacetime symmetry group. We provide an example to illustrate the explanatory nature of RBW and conclude by explaining how RBW deflates "quantum mysteries."Comment: Accepted for publication in Physics Essays. 22 pages text, 13 figure

How to foster Sustainable Continuous Improvement: A cause-effect relations map of Lean soft practices

Lean Management (LM) represents a complex socio-technical system where both technical and social practices should be consistently implemented and integrated in order to foster a Continuous Improvement (CI) culture. Despite initial gains in operational performances due to the implementation of the most common and well-established Lean techniques, the great majority of the companies approaching Lean Manufacturing fail in achieving sustainable outcomes in the long term, and most of them eventually come back to their traditional way of doing business. Recognized the pivotal role of soft practices, the purpose of this study is to investigate the role played by the human factor in fostering the establishment of a Sustainable Continuous Improvement (SCI) environment. Starting from surveying the literature, a comprehensive framework including all the relevant soft practices related to LM has been developed. Then, authors proposed, for the first time, Decision-Making Trail and Evaluation Laboratory (DEMATEL) analysis applied to soft practices of SCI, that provides an innovative understanding of the relevant soft practices which foster SCI by showing cause-effect association among them. The proposed methodology reveals precious insights for scholars and practitioners who intend to approach and apply SCI. The impact relations map shows that some soft practices are initiators and some others enablers of the SCI and allows to identify the most relevant Critical Success Factors (CSF) and interrelationships amongst them. Results show that the key for a SCI is represented by a full engagement of the workforce, which must be triggered and supported by Top Management with the use of some leverages such as an effective communication, training and use of Kaizen events