George Churukian

This picture of Dr. Churukian was taken from the 1983 Wesleyana. His interview is available at http://digitalcommons.iwu.edu/oral_hist/49/https://digitalcommons.iwu.edu/oralhistory_gallery/1091/thumbnail.jp

George Churukian

This picture was provided by Dr. Churukian for posting with his interview which is available at http://digitalcommons.iwu.edu/oral_hist/49/.https://digitalcommons.iwu.edu/oralhistory_gallery/1090/thumbnail.jp

Carol Churukian

Churukian was a friend of a person Myers cultivated as a donor: Pearl Funk, who also possessed book collections. She shares a story of hosting them both for a dinner in her home and recalls that Myers excluded hosts Carol and her husband George from his focus that evening. Churukian recalls that Funk told her later that Myers called Funk from San Francisco to ask if she wanted him to purchase a specific title he spotted for her

George Churukian

Dr. Churukian joined IWU\u27s faculty as Director of the Secondary Education program in 1976 and retired in 1993. He became active in the International Society for Teacher Education before retiring and has enjoyed a long post-career of activity with this and local community groups

Senior Recital: James A. Stombres, Trumpet; Carol Churukian, Piano; April 13, 1977

Hayden AuditoriumWednesday EveningApril 13, 19778:00 p.m

Silver diagnosis in neuropathology: principles, practice and revised interpretation

Silver-staining methods are helpful for histological identification of pathological deposits. In spite of some ambiguities regarding their mechanism and interpretation, they are widely used for histopathological diagnosis. In this review, four major silver-staining methods, modified Bielschowsky, Bodian, Gallyas (GAL) and Campbell–Switzer (CS) methods, are outlined with respect to their principles, basic protocols and interpretations, thereby providing neuropathologists, technicians and neuroscientists with a common basis for comparing findings and identifying the issues that still need to be clarified. Some consider “argyrophilia” to be a homogeneous phenomenon irrespective of the lesion and the method. Thus, they seek to explain the differences among the methods by pointing to their different sensitivities in detecting lesions (quantitative difference). Comparative studies, however, have demonstrated that argyrophilia is heterogeneous and dependent not only on the method but also on the lesion (qualitative difference). Each staining method has its own lesion-dependent specificity and, within this specificity, its own sensitivity. This “method- and lesion-dependent” nature of argyrophilia enables operational sorting of disease-specific lesions based on their silver-staining profiles, which may potentially represent some disease-specific aspects. Furthermore, comparisons between immunohistochemical and biochemical data have revealed an empirical correlation between GAL+/CS-deposits and 4-repeat (4R) tau (corticobasal degeneration, progressive supranuclear palsy and argyrophilic grains) and its complementary reversal between GAL-/CS+deposits and 3-repeat (3R) tau (Pick bodies). Deposits containing both 3R and 4R tau (neurofibrillary tangles of Alzheimer type) are GAL+/CS+. Although no molecular explanations, other than these empiric correlations, are currently available, these distinctive features, especially when combined with immunohistochemistry, are useful because silver-staining methods and immunoreactions are complementary to each other